Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

for Bronchiectasis With Pseudomonas Aeruginosa Colonization

25 locations incl. Orange

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07088926·Phase 2·Recruiting

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Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Brivekimig

13 locations incl. Scottsdale

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07170917·Phase 2·Recruiting

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A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

for Non-muscle Invasive Bladder Cancer

39 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07206225·Phase 1·Recruiting

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Technology-Enhanced Therapy vs. Medication Monitoring for Buprenorphine Retention in Pregnant Persons

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 18 - 45

Code: NCT06999811·Recruiting

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Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for Neovascular Age-related Macular Degeneration

Drug: Surabgene Lomparvovec

53 locations incl. Mesa

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT07007065·Phase 3·Recruiting

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

260 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting

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Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

for Wound Healing and Prevention

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07095556·Recruiting

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Examining Whether Project Support Works

for Parent-Child Relations

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 6 - 13

Code: NCT06963554·Recruiting

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A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

for Nonsegmental Vitiligo

Drug: Zasocitinib

23 locations incl. Bryant

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT07108283·Phase 2·Recruiting

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Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)

for Spinal Cord Injuries and Disorders (SCI/D)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07179822·Recruiting

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A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

for Smoking

Drug: Brenipatide

16 locations incl. Rogers

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07223840·Phase 2·Recruiting

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A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

31 locations incl. Phoenix

Sponsor: Bluefin Biomedicine, Inc.

Sex: All·Age: 18 - 75

Code: NCT07287644·Phase 2, Phase 3·Recruiting

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De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

for Congenital Diaphragmatic Hernia

19 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 Months - 1 Month

Code: NCT05213676·Phase 4·Recruiting

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SAINT in Postpartum Depression (PPD)

for Postpartum Depression (PPD)

4 locations incl. Worcester

Sponsor: Magnus Medical

Sex: Female·Age: 18 - 45

Code: NCT07210255·Recruiting

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Closed-loop rTMS-EEG During Visuomotor Integration.

for Visuomotor Skills

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07249801·Recruiting

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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

for Uncontrolled Hypertension

20 locations incl. San Jose

Sponsor: Retension Pharmaceuticals. Inc.

Sex: All·Age: 18 - 70

Code: NCT07142356·Phase 2·Recruiting

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

50 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting

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Preoperative Acetazolamide

for Post Operative Pain

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: Female·Age: 21 - 65

Code: NCT07101250·Phase 4·Recruiting

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Intracervical Vasopressin

for Retained Products of Conception

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: Female·Age: 18 - 51

Code: NCT07102615·Phase 4·Recruiting

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A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis

for Bronchiectasis

14 locations incl. Mobile

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 85

Code: NCT07201051·Phase 2·Recruiting

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A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

for Prostate Cancer Patients Treated by Radiotherapy

7 locations incl. Peoria

Sponsor: Candel Therapeutics, Inc.

Sex: Male·Age: 18+

Code: NCT07332000·Phase 2·Recruiting

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SPI-1005 for the Treatment of Meniere's Disease (Open Label)

for Meniere's Disease

9 locations incl. Los Angeles

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18 - 75

Code: NCT06859788·Phase 3·Recruiting

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Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

for Geographic Atrophy (GA)

27 locations incl. Gilbert

Sponsor: ONL Therapeutics

Sex: All·Age: 55+

Code: NCT06659445·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Bevacizumab

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting

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OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

for Cardiac Failure

7 locations incl. Los Angeles

Sponsor: Inova Health Care Services

Sex: All·Age: 18 - 99

Code: NCT06939751·Recruiting

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Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery

for Unilateral Vocal Cord Paralysis

10 locations incl. La Jolla

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07579364·Enrolling By Invitation

RaDIANT Health Systems Intervention

for End Stage Renal Disease (ESRD)

5 locations incl. Atlanta

Sponsor: Indiana University

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07033117·Recruiting

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Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain

for Lower Back Pain

2 locations incl. Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07166952·Recruiting

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A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

for Ovarian Neoplasms

82 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

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NeoCARD: Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Patients

for Triple Negative Breast Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06845319·Phase 2·Recruiting

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Evaluating the Long-term Safety and Tolerability of Imatinib in Patients With Lymphangioleiomyomatosis (LAM)

for Lymphangioleiomyomatosis (LAM)

2 locations incl. New York

Sponsor: Columbia University

Sex: Female·Age: 18 - 64

Code: NCT06889168·Phase 1·Recruiting

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Proof of Concept Study to Assess the Pharmacokinetics/Pharmacodynamics of Nemolizumab in Adults With Chronic Pruritus of Unknown Origin (CPUO)

for Chronic Pruritus of Unknown Origin

Drug: Nemolizumab

25 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT07074977·Phase 2·Recruiting

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STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

for Tobacco Use

4 locations incl. Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06922617·Recruiting

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Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

376 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting

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A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

for Metabolic Dysfunction-Associated Steatotic Liver Disease

140 locations incl. Tuscaloosa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07165028·Phase 3·Recruiting

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Long-Term Stability of the Glide Control Strategy

for Upper Limb Amputation Above Elbow

10 locations incl. Annapolis

Sponsor: Infinite Biomedical Technologies

Sex: All·Age: 18+

Code: NCT07222085·Recruiting

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A Trial of Varenicline for E-cigarette Cessation

for E-cigarette Use

2 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07040566·Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients

for Knee Osteoarthritis

8 locations incl. Birmingham

Sponsor: Doron Therapeutics Inc.

Sex: All·Age: 40 - 80

Code: NCT07219771·Phase 3·Recruiting

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A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin

for Diabetes Mellitus, Type 2

20 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT07215312·Phase 2·Recruiting

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A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

for Insomnia

11 locations incl. New Haven

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 70

Code: NCT06655883·Phase 3·Recruiting

Apply to this trial