Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for Miscellaneous Neoplasm, Nos

231 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07091617·Recruiting

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A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for Clostridioides Difficile Associated Disease

135 locations incl. Athens

Sponsor: Pfizer

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07282665·Phase 3·Recruiting

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A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

for Psoriatic Arthritis

Drug: Bimekizumab

28 locations incl. Peoria

Sponsor: UCB Biopharma SRL

Sex: All·Age: 18+

Code: NCT07290036·Phase 1·Recruiting

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A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

for Bladder Cancer

2 locations incl. Bakersfield

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07222488·Phase 1, Phase 2·Recruiting

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Pharmacokinetics, Safety, and Tolerability Study of GOPRELTO® Nasal Solution and NUMBRINO™ Nasal Solution

for ENT Disorder

4 locations incl. Columbia

Sponsor: Noden Pharma

Sex: All·Age: 12 - 18

Code: NCT04792034·Phase 3·Recruiting

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A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis

for Plaque Psoriasis

Drug: Zasocitinib

11 locations incl. Chula Vista

Sponsor: Takeda

Sex: All·Age: 4 - 17

Code: NCT07250802·Phase 3·Recruiting

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A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

for Gastrointestinal Neoplasms

35 locations incl. Phoenix

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07218926·Phase 3·Recruiting

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A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Cancer

9 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: Male·Age: 18+

Code: NCT07244341·Phase 1·Recruiting

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A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema

for Atopic Dermatitis

7 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 2 - 11

Code: NCT06807281·Phase 3·Recruiting

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Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for Castration-Sensitive Prostate Carcinoma

Drug: Apalutamide

194 locations incl. Tucson

Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male·Age: 18+

Code: NCT06931340·Phase 3·Recruiting

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Evaluating the Communication Between Patients and Providers in Cancer Clinics

for Cancer

3 locations incl. Chicago

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT06985953·Recruiting

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Transcutaneous Electrical Nerve Stimulation for Pain Mitigation During Intrauterine Device Placement

for Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 18+

Code: NCT06991075·Recruiting

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Formoterol in Diabetes

for Diabetic Nephropathies

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT07022418·Phase 2·Recruiting

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A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)

for Inflammatory Arthritis

6 locations incl. Phoenix

Sponsor: Smith & Nephew, Inc.

Sex: All·Age: 18 - 80

Code: NCT07199738·Not Yet Recruiting

Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Upper Extremities

for Actinic Keratosis

20 locations incl. Phoenix

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144852·Phase 3·Recruiting

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Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

for Type 2 Diabetes

52 locations incl. Chandler

Sponsor: Sparrow Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07296484·Phase 2·Recruiting

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An Evaluation of the PureWick™ Male External Catheter Versus an Established Comparator Overnight in the Home Setting for Incontinence in Adult Males

for Urinary Incontinence

8 locations incl. Guntersville

Sponsor: C. R. Bard

Sex: Male·Age: 18+

Code: NCT07282860·Enrolling By Invitation

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

for Metastatic Castration-resistant Prostate Cancer

13 locations incl. San Francisco

Sponsor: K36 Therapeutics, Inc.

Sex: Male·Age: 18+

Code: NCT07103018·Phase 1·Recruiting

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Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

75 locations incl. Birmingham

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT07231419·Phase 3·Recruiting

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Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp

for Actinic Keratosis

10 locations incl. Fremont

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144345·Phase 3·Recruiting

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A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: 6 Months - 17

Code: NCT07188805·Phase 3·Recruiting

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Study of 30-Minute Stimulation With the Neuspera Sacral Neuromodulation (SNM) System

for Urinary Urge Incontinence

1 location in West Columbia

Sponsor: Neuspera Medical, Inc.

Sex: All·Age: 22+

Code: NCT07247136·Recruiting

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A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

for Non Small Cell Lung Cancer

11 locations incl. San Francisco

Sponsor: Rondo Therapeutics

Sex: All·Age: 18+

Code: NCT07218003·Phase 1·Enrolling By Invitation

This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment

for Atopic Dermatitis

43 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT07290803·Recruiting

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BabySTrong II taVNS Feeding Trial

for Feeding Delays

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 39 Weeks - 54 Weeks

Code: NCT07049952·Phase 2, Phase 3·Recruiting

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Bright Light Therapy for Depressed Geriatric Inpatients

for Unipolar Depression

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 60+

Code: NCT07002554·Phase 2·Enrolling By Invitation

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

12 locations incl. Phoenix

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 69

Code: NCT07085104·Phase 1·Recruiting

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A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

for Hidradenitis Suppurativa

Drug: Ritlecitinib

32 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 18 - 75

Code: NCT07228390·Phase 2·Recruiting

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A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

42 locations incl. Mobile

Sponsor: Incyte Corporation

Sex: Female·Age: 18 - 99

Code: NCT07023627·Phase 2·Recruiting

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A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for Alzheimers Disease

Drug: Trontinemab

33 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07170150·Phase 3·Recruiting

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Remimazolam vs Propofol in Laser Burn Cases

for Burn Scar

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07213544·Phase 4·Recruiting

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Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder

for Nicotine Use Disoder

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: All·Age: 21+

Code: NCT07594717·Recruiting

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A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis (SPMS)

Drug: Remibrutinib

30 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07225504·Phase 3·Recruiting

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A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

for Eosinophilic Esophagitis (EoE)

Drug: Dupilumab

10 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 6 Months - 6

Code: NCT07112378·Phase 3·Recruiting

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LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

for Ulcerative Colitis

Drug: LY4268989

41 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07186101·Phase 2·Recruiting

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sTMS Combined With CIMT and taVNS In Infants With Hemiplegia

for Hemiplegia

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 8 Months - 24 Months

Code: NCT07063446·Recruiting

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Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

for Chronic Pain

7 locations incl. Greenwood

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07190807·Recruiting

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Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

for Osteoarthritis Knee Pain

20 locations incl. San Diego

Sponsor: Saol Therapeutics Inc

Sex: All·Age: 40+

Code: NCT07226258·Phase 3·Recruiting

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Development of Optical Biometer

for Cataract and IOL Surgery

1 location in Hilton Head Island

Sponsor: Cassini Technologies

Sex: All·Age: 18+

Code: NCT07325162·Recruiting

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

148 locations incl. Loma Linda

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting

Apply to this trial