Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder

Part of paid clinical trials in Greenville, South Carolina.

Sponsor
Prisma Health-Upstate
Study ID
NCT07594717
Status
Recruiting
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Conditions

  • Nicotine Use Disoder
  • Opioid Use Disorder

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Sweet-cooling — DRUG
    Sweet-cooling EC flavor
  • Sweet non-cooling EC flavor — DRUG
    Sweet non-cooling flavor
  • Tobacco flavor EC — DRUG
    Tobacco flavor EC

Study Details

This study examines the effects of e-cigarette (EC) flavors among adults with opioid use disorder (OUD) receiving buprenorphine treatment who currently use e-cigarettes. Participants will smell and rate 11 EC flavors based on appeal, sensory characteristics, and likelihood of future use. Researchers will examine how different flavor profiles influence the appeal and reinforcing effects of ECs in this population. The goal is to identify EC flavors that may enhance the acceptability of ECs as a potential harm-reduction strategy among adults with OUD receiving buprenorphine treatment.

Key Dates

Start date
Nov 12, 2025
Status verified
May 2026
Primary completion
May 31, 2026
Completion
May 31, 2026

Study Design

Enrollment
70 participants (estimated)

Primary Outcome Measure

Perceived Sweetness [ Time Frame: Baseline session ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Prisma Health Recovery Clinic-GreenvilleGreenvilleSouth Carolina29605
Alain Litwin, MD
[email protected]
(864) 455-5994

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By research site
Prisma Health Recovery Clinic-Greenville· Greenville, SC

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