A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

Part of paid clinical trials in Peoria, Arizona.

Sponsor
UCB Biopharma SRL
Study ID
NCT07290036
Phase
PHASE1
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

To demonstrate that bimekizumab administered intravenously is noninferior to subcutaneous administration.

Key Dates

Start date
Dec 10, 2025
Status verified
Jun 2026
Primary completion
May 18, 2028
Completion
Sep 14, 2028

Study Design

Enrollment
392 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Bimekizumab arm 1
    Subjects participating in the study will receive assigned bimekizumab dosing regimen 1 or 2 during the PK Lead-In Phase and dosing regimen 1 or 2 during Treatment Period.
  • Experimental: Bimekizumab arm 2
    Subjects participating in the study will receive assigned bimekizumab dosing regimen 3 during the PK Lead-In Phase and dosing regimen 3 during Treatment Period.

Primary Outcome Measure

Steady-state Trough Concentration (Ctrough,ss) at Week 16 [ Time Frame: Week 16 ]

Central Contacts

Locations (28)

FacilityCityStateZIPSite coordinators
Pa0019 114PeoriaArizona85381-5025-
Pa0019 127Apple ValleyCalifornia92307-
Pa0019 111CovinaCalifornia91722-
Pa0019 117RiversideCalifornia92518-
Pa0019 125San LeandroCalifornia94578-
Pa0019 126TemeculaCalifornia92592-
Pa0019 141UplandCalifornia91786-
Pa0019 120WhittierCalifornia90602-
Pa0019 128WhittierCalifornia90602-
Pa0019 123Fort CollinsColorado80528-
Pa0019 143Ormond BeachFlorida32174-
Pa0019 113South MiamiFlorida33155-
Pa0019 132ChicagoIllinois60661-
Pa0019 134LansingMichigan48911-
Pa0019 140West Long BranchNew Jersey07764-1503-
Pa0019 131AlbuquerqueNew Mexico87102-
Pa0019 144VandaliaOhio45377-
Pa0019 115DuncansvillePennsylvania16635-
Pa0019 142Rock HillSouth Carolina29732-
Pa0019 116JacksonTennessee38305-
Pa0019 138MurfreesboroTennessee37128-
Pa0019 129BaytownTexas77521-
Pa0019 136ColleyvilleTexas76034-
Pa0019 135MesquiteTexas75150-
Pa0019 124PlanoTexas75075-
Pa0019 121BellevueWashington98004-
Pa0019 145SpokaneWashington99216-
Pa0019 130BeckleyWest Virginia25801-

Find similar trials in Peoria, AZ

By condition
Psoriatic arthritis
By specialty
RheumatologyAutoimmune diseaseMusculoskeletal disorders
By research site
Pa0019 114· Peoria, AZPa0019 127· Apple Valley, CAPa0019 111· Covina, CAPa0019 117· Riverside, CAPa0019 125· San Leandro, CAPa0019 126· Temecula, CA

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