Preoperative Acetazolamide

Part of paid clinical trials in Greenville, South Carolina.

Sponsor
Prisma Health-Upstate
Study ID
NCT07101250
Phase
PHASE4
Status
Recruiting
Apply to this trial

Conditions

  • Laparoscopic Hysterectomy
  • Post Operative Pain
  • Referred Pain

Eligibility Criteria

Sex
FEMALE
Age
21 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Acetazolamide 500 MG Extended Release Oral Capsule — DRUG
    Active Drug
  • Placebo — DRUG
    Inactive Drug

Study Details

The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from the gas used in the abdomen during the laparoscopic procedure. Patients will be asked to rate their pain before surgery and after surgery through 24 hours.

Key Dates

Start date
Oct 30, 2025
Status verified
Jul 2025
Primary completion
Aug 1, 2026
Completion
Nov 1, 2026

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Active Comparator: Active Drug
    Acetazolamide 500mg ER
  • Active Comparator: Placebo
    Inactive Placebo Capsule

Primary Outcome Measure

Abdominal/pelvic pain and right subscapular pain rated on a VAS at five perioperative points [ Time Frame: From before procedure to 24 hours post procedure ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Prisma HealthGreenvilleSouth Carolina29605
Patti Parker, BSN
[email protected]
864-455-1510

Find similar trials in Greenville, SC

By research site
Prisma Health· Greenville, SC

Related Studies