Clinical Trials at University of Pittsburgh

As of June 2026, 166 paid clinical trials are recruiting at University of Pittsburgh, located at University of Pittsburgh Medical, 580 S Aiken Ave, Pittsburgh, PA 15232, phone (412) 687-3355 in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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166 clinical trials at University of Pittsburgh

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The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy

for Anti-3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy

5 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 16+

Code: NCT06599697·Phase 2·Recruiting

Apply to this trial

Autologous Fresh Fat Grafting Followed by Autologous Cryopreserved Fat Grafting

for Facial Defect

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06747715·Recruiting

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Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder

for Central Sleep Apnea Comorbid With Opioid Use

1 location in Pittsburgh

Sponsor: Sanjay R Patel

Sex: All·Age: 18 - 100

Code: NCT06521476·Phase 2·Recruiting

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Rehabilitation Strategies for Social Participation in Chronic Stroke Survivors

for Stroke

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06758505·Recruiting

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Technology Assisted Collaborative Care Intervention to Improve Patient-centered Outcomes in Dialysis Patients

for Chronic Kidney Disease Requiring Hemodialysis

2 locations incl. Albuquerque

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06978127·Recruiting

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Near-InfraRed Spectroscopy of Auricular Stimulation

for Healthy Male and Female Subjects

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06825364·Recruiting

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Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

for Sickle Cell Disease Vaso-occlusive Crisis

16 locations incl. Oakland

Sponsor: CSL Behring

Sex: All·Age: 12+

Code: NCT06699849·Phase 2·Recruiting

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Improving Mobility After Revascularization in Peripheral Artery Disease

for Peripheral Artery Disease

7 locations incl. Tucson

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06686121·Phase 3·Recruiting

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AuriculoTherapy NeuroImaging

for Low Back Pain

1 location in Pittsburgh

Sponsor: Keith M Vogt

Sex: All·Age: 18+

Code: NCT06825390·Recruiting

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Project VIBE: Virtual Intervention for Binge Eating in Adolescents

for Obesity

2 locations incl. Chicago

Sponsor: University of Pittsburgh

Sex: All·Age: 13 - 19

Code: NCT06819813·Recruiting

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A Study to Evaluate the SENSE Device's Ability to Detect TBI

for Traumatic Brain Injury

6 locations incl. Gainesville

Sponsor: Sense Diagnostics, LLC

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT06828107·Recruiting

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The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

for Autism

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 6 - 10

Code: NCT06386029·Recruiting

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Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

for Stroke

1 location in Pittsburgh

Sponsor: Jorge Gonzalez-Martinez

Sex: All·Age: 18 - 75

Code: NCT06303869·Recruiting

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Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems

for Peripheral Neuropathies

6 locations incl. Mesa

Sponsor: RxFunction Inc.

Sex: All·Age: 55+

Code: NCT06959277·Recruiting

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Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke

for Stroke

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06458153·Recruiting

Apply to this trial

Assessing Improvements in Mood and Sleep Trial

for Depression

3 locations incl. Los Angeles

Sponsor: University of Pittsburgh

Sex: All·Age: 55+

Code: NCT06639477·Recruiting

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Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

for Sleep Disturbance

2 locations incl. Philadelphia

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 18

Code: NCT06963463·Recruiting

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Helping Adults With Type 2 Diabetes Use Their Health Data for Healthy Diabetes Self-Management

for Type 2 Diabetes Mellitus (T2DM)

1 location in Pittsburgh

Sponsor: Ann-Marie Rosland

Sex: All·Age: 25 - 75

Code: NCT06848361·Enrolling By Invitation

Impact of Brief Daily Functional Resistance Training on Lower Extremity Physical Performance

for Mobility Limitation

2 locations incl. Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 65+

Code: NCT06396247·Phase 2, Phase 3·Recruiting

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Teen Brain Online II: Understanding How Social Media Affects the Teen Brain

for Depression

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13 - 17

Code: NCT06817993·Recruiting

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Machine-Learning Prediction and Reducing Overdoses With EHR Nudges

for Opioid Overdose

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06806163·Recruiting

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Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs

for Cardiac Failure

7 locations incl. Aurora

Sponsor: Inova Health Care Services

Sex: All·Age: Up to 18

Code: NCT06532890·Recruiting

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An Evaluation of the Impact of Pharmacist Personalized Medication Reviews With and Without a Discussion of Pharmacogenomic Results in an Employee Health Program.

for Pharmacogenetics

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06660264·Enrolling By Invitation

Effectiveness of VestAid App

for MTBI - Mild Traumatic Brain Injury

1 location in Pittsburgh

Sponsor: BlueHalo

Sex: All·Age: 18 - 60

Code: NCT06683417·Not Yet Recruiting

Nitrous Oxide Neuroimaging

for Anesthesia

1 location in Pittsburgh

Sponsor: Keith M Vogt

Sex: All·Age: 18 - 59·Accepts healthy volunteers

Code: NCT06702631·EARLY_Phase 1·Recruiting

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Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

for Inflammatory Bowel Diseases

20 locations incl. Birmingham

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06560021·Enrolling By Invitation

Sleep Promotion Program Primary Care

for Sleep

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 18

Code: NCT06240325·Recruiting

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Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

for Pancreatic Carcinoma

9 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06271291·Recruiting

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Centering Gender Affirming Resources in Higher Education

for Sexual Violence

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06390332·Recruiting

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Feasibility of Resting Intervals During Exercise Programs for Individuals With Knee Osteoarthritis

for Knee Osteoarthristis

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 45 - 79

Code: NCT06857123·Recruiting

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OurSleepKit To Support CPAP Adherence

for Obstructive Sleep Apnea

2 locations incl. Boston

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18+

Code: NCT06621511·Recruiting

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A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

12 locations incl. Birmingham

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05552157·Phase 2, Phase 3·Recruiting

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A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

12 locations incl. Birmingham

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06647498·Phase 2, Phase 3·Recruiting

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Dyadic Sleep Study

for Gastrointestinal Cancer

2 locations incl. Coral Gables

Sponsor: University of Miami

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06569693·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

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Strategy Training and Pets to Promote Stroke Survivor's Cognitive Performance and Community Participation

for Stroke

1 location in Pittsburgh

Sponsor: University of Haifa

Sex: All·Age: 18+

Code: NCT05098730·Not Yet Recruiting

Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

for Huntington Disease

13 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 60

Code: NCT06667414·Recruiting

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School Partnered Collaborative Care (SPACE) Intervention for Children With Type 1 Diabetes

for Type 1 Diabetes

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 5 - 12

Code: NCT06420661·Enrolling By Invitation

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

for Traumatic Brain Injury

18 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 65

Code: NCT05826912·Phase 2·Enrolling By Invitation

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

for Gestational Diabetes Mellitus

21 locations incl. Tuscaloosa

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT06445946·Phase 4·Recruiting

Apply to this trial