Paid Clinical Trials in Philadelphia, PA

As of June 2026, 2,103 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,101 clinical trials

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Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for Surgery-Complications

20 locations incl. Little Rock

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05991453·Recruiting

Apply to this trial

Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea

for Obstructive Sleep Apnea of Adult

9 locations incl. Aurora

Sponsor: Cryosa, Inc.

Sex: All·Age: 22 - 70

Code: NCT06008626·Recruiting

Apply to this trial

Cryoablation for Monomorphic Ventricular Tachycardia

for Sustained VT

13 locations incl. Phoenix

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT05675865·Recruiting

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Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

for Community-acquired Pneumonia

19 locations incl. Mobile

Sponsor: Biotest

Sex: All·Age: 18+

Code: NCT05722938·Phase 3·Recruiting

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Comparison of Uncomplicated Candidemia Therapy Duration in Children

for Invasive Candidiasis

21 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 120 Days+

Code: NCT05763251·Recruiting

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To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis

for End Stage Renal Disease (ESRD)

32 locations incl. Scottsdale

Sponsor: Humacyte, Inc.

Sex: Female·Age: 18+

Code: NCT05908084·Phase 3·Recruiting

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Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for Primary Biliary Cholangitis

49 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06051617·Phase 3·Recruiting

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Nurturing Needs Study: Parenting Food Motivated Children

for Parenting

2 locations incl. Philadelphia

Sponsor: Temple University

Sex: All·Age: 4 - 5·Accepts healthy volunteers

Code: NCT06111040·Recruiting

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Can Medical Cannabis Affect Opioid Use?

for Chronic Pain

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06206252·Recruiting

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Excision of Lymph Node Trial (EXCILYNT) (Mel69)

for Melanoma

7 locations incl. Atlanta

Sponsor: Craig L Slingluff, Jr

Sex: All·Age: 18+

Code: NCT05839912·Recruiting

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A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease

for Danon Disease

3 locations incl. La Jolla

Sponsor: Rocket Pharmaceuticals Inc.

Sex: Male·Age: 8+

Code: NCT06092034·Phase 2·Recruiting

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SPEARHEAD-3 Pediatric Study

for Synovial Sarcoma

10 locations incl. Palo Alto

Sponsor: USWM CT, LLC

Sex: All·Age: 2 - 21

Code: NCT05642455·Phase 1, Phase 2·Recruiting

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A Trial of Post-Discharge Transitional Care for Patients With Chronic Liver Disease

for Liver Diseases

4 locations incl. Chicago

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05733832·Recruiting

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Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana

for Cervical Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT05952141·Recruiting

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Clinical Data Registry of Amblyopia Patients on Luminopia Treatment

for Amblyopia

13 locations incl. San Ramon

Sponsor: Luminopia

Sex: All·Age: All ages

Code: NCT06429280·Recruiting

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HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

for Erythropoietic Protoporphyria

11 locations incl. Birmingham

Sponsor: Disc Medicine, Inc

Sex: All·Age: 12+

Code: NCT05883748·Phase 2, Phase 3·Enrolling By Invitation

Study of AVZO-021 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. New Haven

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05867251·Phase 1, Phase 2·Recruiting

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STXBP1 and SYNGAP1 Related Disorders Natural History Study

for Genetic Disease

5 locations incl. Palo Alto

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT06555965·Recruiting

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A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

for PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)

3 locations incl. La Jolla

Sponsor: Rocket Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT05885412·Phase 1·Recruiting

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Tazemetostat and Palbociclib With CPX-351for R/R AML

for Recurrent Acute Myeloid Leukemia

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05627232·Phase 1·Recruiting

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Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

for Heart Failure

47 locations incl. Phoenix

Sponsor: Procyrion

Sex: All·Age: 21+

Code: NCT05677100·Recruiting

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ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

for X-linked Retinoschisis

4 locations incl. Los Angeles

Sponsor: Atsena Therapeutics Inc.

Sex: All·Age: 6+

Code: NCT05878860·Phase 3·Recruiting

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Responding With Evidence and Access for Childhood Headaches

for Headache

15 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 10 - 17

Code: NCT05889624·Recruiting

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A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: PF-07275315

52 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05995964·Phase 2·Recruiting

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Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

for Cholangiocarcinoma

Drug: Trametinib

10 locations incl. Los Angeles

Sponsor: Genfit

Sex: All·Age: 18+

Code: NCT05874414·Phase 1, Phase 2·Recruiting

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Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis

for Sepsis

4 locations incl. Atlanta

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT05975671·Recruiting

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Exparel vs Block for ACL Reconstruction

for ACL

1 location in Philadelphia

Sponsor: Rothman Institute Orthopaedics

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06006624·Phase 4·Enrolling By Invitation

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

for Cardiovascular Disorder

31 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 7+

Code: NCT05705531·Recruiting

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A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

120 locations incl. Mobile

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting

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Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

for Hypertrophic Cardiomyopathy

10 locations incl. La Jolla

Sponsor: Tenaya Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05836259·Phase 1, Phase 2·Recruiting

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Disentangling the Role of Depression in Hypersomnia

for Hypersomnia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 55

Code: NCT05850676·Recruiting

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Adaptive Radiation for Abdominopelvic Metastases

for Neoplasm - Soft Tissue Pelvis Malignant Secondary

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT05880667·Phase 1·Recruiting

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Diet and Motility in IBS

for Irritable Bowel Syndrome (IBS)

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 8 - 18·Accepts healthy volunteers

Code: NCT07283341·Recruiting

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A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

for Type 1 Diabetes Mellitus With Hypoglycemia

38 locations incl. Birmingham

Sponsor: Zucara Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT05762107·Phase 2·Recruiting

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Trauma Resuscitation With Low-Titer Group O Whole Blood or Products

for Wounds and Injuries

13 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 15+

Code: NCT05638581·Phase 3·Recruiting

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Lurbinectedin in FET-Fused Tumors

for Ewing Sarcoma

Drug: Lurbinectedin

6 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10+

Code: NCT05918640·Phase 1, Phase 2·Recruiting

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A Registry for People With T-cell Lymphoma

for T-cell Lymphoma

26 locations incl. Duarte

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: All ages

Code: NCT05978141·Recruiting

Apply to this trial

Food Genetics Behavior Study

for Obesity, Childhood

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 5 - 7·Accepts healthy volunteers

Code: NCT05783765·Recruiting

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Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

for Lung Cancer, Nonsmall Cell

Drug: Atezolizumab

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04691817·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

for Solid Tumors

11 locations incl. Los Angeles

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05836324·Phase 1·Recruiting

Apply to this trial