Food Genetics Behavior Study

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
University of Pennsylvania
Study ID
NCT05783765
Status
Recruiting
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Conditions

  • Obesity, Childhood

Eligibility Criteria

Sex
ALL
Age
5 Years - 7 Years
Healthy Volunteers
Accepted

Interventions

  • Heightened Drive to Eat — BEHAVIORAL
    Participants' eating rate and eating in the absence of hunger will be assessed during a videotaped experimental meal. The relative reinforcing value of food will be assessed using a computerized behavioral choice task.

Study Details

A genetic risk for obesity does not always translate to the development of obesity among children, which points to the presence of risk-modifying factors that likely relate to energy balance behaviors as key behavioral drivers. Using an integrated approach to comprehensively examine the interplay between genotype and phenotype, this study will systematically assess the extent to which energy balance behaviors, alone or in combination, in conjunction with family-level influences can modify behavioral and genetic predispositions to childhood obesity in a high-risk sample of predominantly minority children from low-resource backgrounds. Identifying protective factors that may mitigate the impact of obesity risk on weight and adiposity outcomes is critical for moving the prevention of childhood obesity into a new direction.

Key Dates

Start date
Jul 26, 2023
Status verified
Oct 2025
Primary completion
Oct 31, 2027
Completion
Oct 31, 2027

Study Design

Enrollment
242 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Experimental: Heightened Drive to Eat
    * Eating rate * Eating in the absence of hunger * Relative reinforcing value of food

Primary Outcome Measure

Body Mass Index (BMI) [ Time Frame: Change from baseline to 1-year follow-up ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Penn Medicine Center for Weight and Eating DisordersPhiladelphiaPennsylvania19104
Ana Coronado
Tanja VE Kral, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Philadelphia, PA

By research site
Penn Medicine Center for Weight and Eating Disorders· Philadelphia, PA

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