Can Medical Cannabis Affect Opioid Use?

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
Thomas Jefferson University
Study ID
NCT06206252
Status
Recruiting
Apply to this trial

Conditions

  • Chronic Pain
  • Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Medical Cannabis — OTHER
    Participants will be restricted to specific medical cannabis products from Ethos Dispensary. They will be randomized to one medical cannabis formulation (tincture or vaporization) for the duration of the study. Each month for three months, they will purchase a different composition (predominantly THC, predominantly CBD, or balanced products) of their designated formulation. The order of compositions will be randomized and double-blinded, so participants and the research team will not know which compositions of medical cannabis they are using each month.

Study Details

The goal of this observational study is to learn how medical cannabis (MC) affects pain and the use of opioid pain medications. Participants who have chronic pain and use prescribed opioid pain medication will opt-in to using MC or not for the 3-month study. Participants who are certified in Pennsylvania will purchase specific medical cannabis products at a reduced cost from a partnering medical cannabis dispensary monthly. All participants will complete baseline, daily, and monthly assessments to observe changes across groups.

Key Dates

Start date
Sep 7, 2023
Status verified
Feb 2025
Primary completion
May 31, 2025
Completion
Jan 31, 2026

Study Design

Enrollment
110 participants (estimated)

Arms

  • Arm: Medical Cannabis Group
    Participants will use designated medical cannabis products for the study duration.
  • Arm: Control Group
    Participants will not use any cannabis for the study duration.

Primary Outcome Measure

Change in pain severity [ Time Frame: Baseline, 4 weeks, 8 weeks, 12 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Thomas Jefferson University HospitalPhiladelphiaPennsylvania19107
Allison Herens, LSW
[email protected]
215-531-4971

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By research site
Thomas Jefferson University Hospital· Philadelphia, PA

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