Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
Abramson Cancer Center at Penn Medicine
Study ID
NCT05952141
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Clinic Outreach — BEHAVIORAL
    A member of the pathology team will contact the referring clinic to communicate the readiness of results.
  • Enhanced Outreach — BEHAVIORAL
    A member of the pathology team will contact both the referring clinic and the patient directly to communicate the readiness of results.
  • Low-Touch Strategy — BEHAVIORAL
    Patient will be sent asynchronous text messaging reminders related to the importance of timely care using framed messaging.
  • High-Touch Strategy — BEHAVIORAL
    Patient will be sent asynchronous text messaging reminders related to the importance of timely care using framed messaging in combination with synchronous telephone-based patient navigation.

Study Details

Investigators will test the effectiveness of adaptive strategies on timely adoption of cervical cancer treatment in Botswana using a pragmatic trial design.

Key Dates

Start date
Sep 1, 2023
Status verified
May 2025
Primary completion
Dec 31, 2026
Completion
Aug 31, 2027

Study Design

Enrollment
610 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
HEALTH_SERVICES_RESEARCH

Arms

  • Experimental: Stage 1 Clinic Outreach + Stage 2 Low Touch
    All participants receive direct clinic outreach to communicate readiness of results (stage 1). Participants who do not attend the clinic by 30 days (non-responders) will receive asynchronous text message reminders using framed messaging (stage 2).
  • Experimental: Stage 1 Clinic Outreach + Stage 2 High Touch
    All participants receive direct clinic outreach to communicate readiness of results (stage 1). Participants who do not attend the clinic by 30 days (non-responders) will receive asynchronous text message reminders using framed messaging in combination with synchronous patient navigation (stage 2).
  • Experimental: Stage 1 Enhanced Outreach + Stage 2 Low-Touch
    All participants receive direct clinic outreach plus enhanced outreach to communicate readiness of results (stage 1). Participants who do not attend the clinic by 30 days (non-responders) will receive asynchronous text message reminders using framed messaging (stage 2).
  • Experimental: Stage 1 Enhanced Outreach + Stage 2 High-Touch
    All participants receive direct clinic outreach plus enhanced outreach to communicate readiness of results (stage 1). Participants who do not attend the clinic by 30 days (non-responders) will receive asynchronous text message reminders using framed messaging in combination with synchronous patient navigation.

Primary Outcome Measure

Adoption [ Time Frame: Within 90 days of randomization ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of PennsylvaniaPhiladelphiaPennsylvania19104-

Find similar trials in Philadelphia, PA

By condition
Cervical cancer
By specialty
OncologyGynecologic oncologyWomen's health
By research site
University of Pennsylvania· Philadelphia, PA

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