Disentangling the Role of Depression in Hypersomnia

Conditions

• Hypersomnia

Eligibility Criteria

Sex

ALL

Age

21 Years - 55 Years

Healthy Volunteers

Not accepted

Interventions

• Sleep study — DIAGNOSTIC_TEST
  Participants will spend two nights in the Penn Sleep Center

Study Details

Individuals who have disorders of hypersomnolence (excessive sleepiness) often report symptoms of depression. The goal of this study is to further understand of the relationship between depression and hypersomnia by examining mood-relevant domains of slow wave sleep and reward function.

Key Dates

Start date

Aug 1, 2023

Status verified

Jul 2025

Primary completion

May 30, 2026

Completion

Jun 30, 2026

Study Design

Enrollment

45 participants (estimated)

Arms

• Arm: Idiopathic Hypersomnia
  Men and women with a current diagnosis of Idiopathic Hypersomnia
• Arm: Hypersomnia Associated with a Psychiatric Disorder
  Men and women with a current diagnosis of Hypersomnia Associated with a Psychiatric Disorder

Primary Outcome Measure

Depression severity [ Time Frame: One time at baseline ]

Central Contacts

• Nayeli Nunez-Cruz
  215-746-3067
  [email protected]

Locations (1)

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