Neurology Clinical Trials in Philadelphia, PA

As of June 2026, 103 paid clinical trials are recruiting for Neurology in Philadelphia, Pennsylvania. Neurology trials investigate disease-modifying therapies for Alzheimer's, Parkinson's, multiple sclerosis, ALS, and stroke recovery alongside symptomatic treatments for epilepsy, migraine, and cognitive decline. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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103 clinical trials for Neurology

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Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

for Ischemic Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 90

Code: NCT04897334·Recruiting

Apply to this trial

Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

31 locations incl. Phoenix

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting

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Localizing Epileptic Networks Using MRI and iEEG

for Epilepsy

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04649008·EARLY_Phase 1·Recruiting

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Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

54 locations incl. Birmingham

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for Parkinson Disease

30 locations incl. Birmingham

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04477785·Recruiting

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HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

81 locations incl. Phoenix

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting

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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for Frontotemporal Lobar Degeneration (FTLD)

25 locations incl. Birmingham

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04363684·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

51 locations incl. Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting

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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for Generalized Myasthenia Gravis

32 locations incl. Birmingham

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT04202341·Recruiting

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Abbott DBS Post-Market Study of Outcomes for Indications Over Time

for Movement Disorders

23 locations incl. Tucson

Sponsor: Abbott Medical Devices

Sex: All·Age: All ages

Code: NCT04071847·Recruiting

Apply to this trial

Parkinson's Disease and Movement Disorders Clinical Database

for Parkinson Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04997642·Recruiting

Apply to this trial

Stroke Thrombectomy and Aneurysm Registry

for Stroke

54 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

Apply to this trial

Epilepsy Learning Healthcare System (ELHS)

for Epilepsy

13 locations incl. Phoenix

Sponsor: Epilepsy Foundation of America

Sex: All·Age: All ages

Code: NCT06265103·Recruiting

Apply to this trial

Longitudinal Early-onset Alzheimer's Disease Study Protocol

for Early Onset Alzheimer Disease

18 locations incl. Sun City

Sponsor: Indiana University

Sex: All·Age: 40 - 64·Accepts healthy volunteers

Code: NCT03507257·Recruiting

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Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

for Seizures

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 18

Code: NCT03419260·Recruiting

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Physiological Effects of N-Acetyl Cysteine in Patients With Multiple Sclerosis

for Multiple Sclerosis

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT03032601·Enrolling By Invitation

Phenotype, Genotype & Biomarkers in ALS and Related Disorders

for Amyotrophic Lateral Sclerosis

13 locations incl. Palo Alto

Sponsor: University of Miami

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT02327845·Enrolling By Invitation

Evaluation of the PACE/PACENET BHL Caregiver Program

for Dementia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT02463708·Enrolling By Invitation

Spinal Cord Injury Registry - North American Clinical Trials Network

for Spinal Cord Injury

13 locations incl. Miami

Sponsor: Robert G. Grossman, MD

Sex: All·Age: 18+

Code: NCT00178724·Recruiting

Apply to this trial

Conditions in Neurology (Philadelphia, PA)

Stroke· 23 Parkinson's disease· 13 Alzheimer's disease· 9 ALS (amyotrophic lateral sclerosis)· 9 Traumatic brain injury (TBI)· 8 Mild cognitive impairment (MCI)· 7 Epilepsy· 7 Multiple sclerosis· 6 Myasthenia gravis· 6 Spinal cord injury· 6 Dementia· 5 Migraine· 5 Cognitive impairment / decline· 4 Aphasia· 3 Movement disorders· 3 Headache· 2 Huntington disease· 2 Essential tremor· 2