Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,656 clinical trials

↓ Download CSV

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

for Smoking

7 locations incl. Maitland

Sponsor: RAI Services Company

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07598136·Recruiting

Apply to this trial

Effects of Ketogenic Diet on Alcohol Intoxication

for Ketogenic Diet

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 50·Accepts healthy volunteers

Code: NCT07602270·Recruiting

Apply to this trial

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for Atypical Teratoid/Rhabdoid Tumor

10 locations incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 21

Code: NCT06465199·Phase 1, Phase 2·Recruiting

Apply to this trial

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

for Ovarian Cancer

5 locations incl. Peoria

Sponsor: Nerviano Medical Sciences

Sex: Female·Age: 18+

Code: NCT06930755·Phase 1·Recruiting

Apply to this trial

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

for Locally Advanced Pancreatic Adenocarcinoma

274 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06998940·Phase 3·Recruiting

Apply to this trial

Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica

for Polymyalgia Rheumatica

9 locations incl. Denver

Sponsor: Sanofi

Sex: All·Age: 50+

Code: NCT07286214·Phase 4·Recruiting

Apply to this trial

Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

14 locations incl. Sacramento

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744·Recruiting

Apply to this trial

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for Cardiovascular Disease and Lipoprotein(a)

Drug: Pelacarsen

115 locations incl. Andalusia

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07517263·Phase 3·Recruiting

Apply to this trial

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for Obesity

Drug: NNC0487-0111

202 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07567001·Phase 3·Not Yet Recruiting

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

for Obesity or Overweight

39 locations incl. Pelham

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07575399·Phase 3·Recruiting

Apply to this trial

A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

for Overweight

48 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07575932·Phase 2·Recruiting

Apply to this trial

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for Major Depressive Disorder

27 locations incl. Gilbert

Sponsor: Definium Therapeutics US, Inc.

Sex: All·Age: 18 - 74

Code: NCT07592689·Phase 3·Recruiting

Apply to this trial

Effects of Operational Naps on Blood Pressure and Performance Among Night Shift Workers

for Shift Work

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07217769·Recruiting

Apply to this trial

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

14 locations incl. Birmingham

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting

Apply to this trial

CEUS Evaluation of Hydrocephalus in Neonates and Infants

for Hydrocephalus in Infants

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Minute - 18 Months

Code: NCT06693752·Phase 2·Recruiting

Apply to this trial

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for Glioblastoma (GBM)

12 locations incl. Springdale

Sponsor: Black Diamond Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07326566·Phase 2·Recruiting

Apply to this trial

AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

for Obesity

Drug: NNC0487-0111

17 locations incl. San Diego

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07571005·Phase 3·Recruiting

Apply to this trial

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

for Obesity

Drug: NNC0487-0111

20 locations incl. Gilbert

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07571109·Phase 3·Recruiting

Apply to this trial

Tele-Exercise to Promote Empowered Movement in Individuals With Spinal Cord Injury

for Spinal Cord Injury

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 75

Code: NCT07022808·Recruiting

Apply to this trial

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

for Common Variable Immunodeficiency (CVID)

1 location in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 5 - 40

Code: NCT07284641·Phase 2·Recruiting

Apply to this trial

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

for Opioid-Induced Respiratory Depression

2 locations incl. San Francisco

Sponsor: NeurOptics Inc

Sex: All·Age: 3 - 17·Accepts healthy volunteers

Code: NCT07573150·Recruiting

Apply to this trial

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

24 locations incl. Dothan

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting

Apply to this trial

Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation

for Repetitive Head Impacts

1 location in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 30 - 70

Code: NCT07050173·Phase 1·Recruiting

Apply to this trial

Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection

for Cystic Fibrosis (CF)

2 locations incl. San Diego

Sponsor: Ghady Haidar

Sex: All·Age: 18+

Code: NCT07275905·Phase 1·Not Yet Recruiting

A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients

for Skin Cancer

2 locations incl. Pittsburgh

Sponsor: Marissa Lobl

Sex: All·Age: 18+

Code: NCT07286318·EARLY_Phase 1·Recruiting

Apply to this trial

Virtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion

for Abortion, First Trimester

2 locations incl. Pittsburgh

Sponsor: Study Investigator

Sex: Female·Age: 18+

Code: NCT07288047·Recruiting

Apply to this trial

Radiotherapy for Refractory Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

2 locations incl. Cherry Hill

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07414550·Recruiting

Apply to this trial

Study of a Smart Sharps Disposal Device in Patients With Hemophilia

for Hemophilia A and B

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07421154·Not Yet Recruiting

Penn State Emergency Medicine CarES: Care-partner Evaluation and Sourcing in the Emergency Department

for Dementia

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 60+

Code: NCT07461168·Not Yet Recruiting

Differences in Rest, Emotion, and Arousal Modulation in Youth

for Autism

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 6 - 10

Code: NCT07476937·Recruiting

Apply to this trial

A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia

for Insomnia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT07542756·Phase 4·Recruiting

Apply to this trial

Pilot Study of a Modified Safety Planning Intervention for Elementary School-Aged Children - Main Study

for Suicidal Ideation

1 location in Philadelphia

Sponsor: Columbia University

Sex: All·Age: 6 - 12

Code: NCT07564583·Enrolling By Invitation

Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD

for Rhinovirus Infection

14 locations incl. Tempe

Sponsor: Altesa Biosciences, Inc.

Sex: All·Age: 40 - 85

Code: NCT07610395·Phase 2·Recruiting

Apply to this trial

Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

16 locations incl. Orange

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting

Apply to this trial

Deep Phenotyping of the Renal Allograft to Prognosticate Clinical Outcomes

for Renal Transplant Rejection

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06438107·Not Yet Recruiting

Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System

for Tricuspid Valve Disease

35 locations incl. Birmingham

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18 - 85

Code: NCT06458907·Not Yet Recruiting

Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure

for Heart Failure With Reduced Ejection Fraction

1 location in Philadelphia

Sponsor: VisCardia Inc.

Sex: All·Age: 18+

Code: NCT06552637·Recruiting

Apply to this trial

Long-term Follow-up Study of Patients Who Received EG110A, a Non-replicative Herpes Simplex Virus 1-derived Gene Therapy

for Urinary Bladder, Overactive

4 locations incl. Downey

Sponsor: EG 427

Sex: All·Age: 18 - 75

Code: NCT07227285·Phase 1, Phase 2·Not Yet Recruiting

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

for Advanced Biliary Tract Cancer

23 locations incl. Duarte

Sponsor: J-Pharma Co., Ltd.

Sex: All·Age: 18+

Code: NCT07265674·Phase 3·Recruiting

Apply to this trial

FIH Lead-in Study of YASO GEL Followed by a Phase 1 Randomized, Double-blind Study to Assess Safety and Pharmacokinetics of YASO GEL

for Early-phase Safety and PK Study of a Vaginal Gel

1 location in Pittsburgh

Sponsor: Yaso Therapeutics Corporation

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07281404·EARLY_Phase 1·Not Yet Recruiting