Collaboration for Down Syndrome Progress (CDP)

Part of paid clinical trials in Orange, California.

Sponsor
RTI International
Study ID
NCT07625579
Status
Recruiting
Apply to this trial

Conditions

  • Chromosome Disorders
  • Down Syndrome
  • Intellectual and Developmental Disabilities

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Study Details

The Collaboration for Down Syndrome Progress (CDP) is a long-term study that follows people with Down syndrome of all ages. The goal is to better understand their health, development, and everyday experiences over time. Participants and their caregivers will answer questions, share medical information, and may give samples like blood or saliva. Some participants may also take part in optional activities such as sleep studies, movement tracking, or brain imaging. By collecting the same types of information at many sites, the CDP will help researchers learn why certain health conditions are more common in people with Down syndrome and how to improve care and quality of life.

Key Dates

Start date
May 1, 2026
Status verified
May 2026
Primary completion
Aug 31, 2029
Completion
Aug 31, 2029

Study Design

Enrollment
1,400 participants (estimated)

Arms

  • Arm: CDP Down Syndrome Cohort
    Individuals with Down syndrome enrolled in the CDP Common Protocol. Participants complete standardized questionnaires, neurobehavioral assessments, medical examinations, and biospecimen collection. Medical records are reviewed, and data are harmonized across all sites. A subset of CDP participants may participate in sleep studies, activity monitoring, imaging and metabolic/endocrine blood collection.

Primary Outcome Measure

Enrollment of Participants into the DS-CDP Common Protocol [ Time Frame: 4 years ]

Central Contacts

Locations (16)

FacilityCityStateZIPSite coordinators
University of California IrvineOrangeCalifornia92868
Christy L Hom, PhD
714-456-5902
University of Colorado Anschutz Medical CampusAuroraColorado80045
Joaquin Espinosa, PhD
303-724-7389
University of MiamiMiamiFlorida33136
Ignacio Tapia, MD, MS
[email protected]
305-243-6641
Kansas University Medical CenterKansas CityKansas66160
Lauren T Ptomey, PhD, RD, LD
[email protected]
913-588-5000
John Hopkins UniversityBaltimoreMaryland21287
Sheela N Magge, MD, MSCE
[email protected]
443-997-5437
University of MinnesotaMinneapolisMinnesota55455
Jason Wolff, PhD
[email protected]
612-625-4166
Washington University in St. LouisSt LouisMissouri63108
Natasha Marrus, MD
[email protected]
314-286-1700
University of North Carolina at Chapel HillChapel HillNorth Carolina27599
Heather Hazlett, PhD
[email protected]
919-966-4099
The Children's Hospital of PhiladelphiaPhiladelphiaPennsylvania19104
Andrea Kelly, MD, MSCE
[email protected]
215-590-3174
The Children's Hospital of PhiladelphiaPhiladelphiaPennsylvania19104
Juhi Pandey, PhD
[email protected]
215-590-7555
University of PittsburghPittsburghPennsylvania15203
Bejamin L Handen, PhD
[email protected]
412-235-5445 Expertise
St. Jude Children's Research HospitalMemphisTennessee38105
Lisa Jacola, PhD, ABPP-CN
[email protected]
901-595-5042
Texas Children's Hosptial/Baylor College of MedicineHoustonTexas77030
Mirjana Maletic-Savatic, MD, PhD
[email protected]
(832) 822-1700
University of Texas Health Science Center at San AntionioSan AntonioTexas78207
Maria Rayas, MD
[email protected]
210-358-5437
University of WashingtonSeattleWashington98195
Stephen Dager, MD
[email protected]
877-408-UWAC
University of Wisconsin-MadisonMadisonWisconsin53705
Sigan Hartley, PhD
[email protected]
608.263.1656

Find similar trials in Orange, CA

By research site
University of California Irvine· Orange, CAUniversity of Colorado Anschutz Medical Campus· Aurora, COUniversity of Miami· Miami, FLKansas University Medical Center· Kansas City, KSJohn Hopkins University· Baltimore, MDUniversity of Minnesota· Minneapolis, MN

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