Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Partial Enteral Nutrition as Therapeutic Augmentation of Advanced Pharmacological Therapy in Patients With Active Crohn's Disease

for Crohn's Disease, Active

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT07356232·Not Yet Recruiting

52-week Open Label Safety-Tolerability Study

for Schizophrenia

23 locations incl. Chandler

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07369154·Phase 3·Not Yet Recruiting

An Evaluation of the Impact of Pharmacist Comprehensive Medication Management With Pharmacogenomic Results to Improve Depression Outcomes in Community Pharmacies.

for Pharmacogenetics

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07373470·Not Yet Recruiting

Image-Guided DBS Programming

for Essential Tremor

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 85

Code: NCT07433699·Phase 1·Not Yet Recruiting

Combined Systemic and Intraperitoneal Chemotherapy for Synchronous Gastric and/or Gastroesophageal Peritoneal Carcinomatosis

for Synchronous Gastric Peritoneal Carcinomatosis

1 location in Pittsburgh

Sponsor: Mohammad Haroon Asif Choudry

Sex: All·Age: 18+

Code: NCT07475286·Phase 2·Not Yet Recruiting

Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum

for Perinatal

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18+

Code: NCT07489443·Not Yet Recruiting

Genetic Information for Families After Tumor Testing Study

for Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07517666·Enrolling By Invitation

A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

for Patient-Reported Outcome Measures (PROMs)

14 locations incl. Stanford

Sponsor: Carelon Research

Sex: All·Age: 12 - 17

Code: NCT07525843·Recruiting

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INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility Study

for Neurological Disorder

5 locations incl. Jacksonville

Sponsor: Synchron, Inc.

Sex: All·Age: 22+

Code: NCT07543367·Recruiting

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Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)

for Abdominal Aortic Aneurysm

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07548099·Recruiting

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A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients

for High-Risk Neuroblastoma

2 locations incl. Aurora

Sponsor: Renaissance Pharma Ltd.

Sex: All·Age: 18 Months - 18

Code: NCT07549321·Phase 2, Phase 3·Recruiting

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Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

for Erythropoietic Protoporphyria (EPP)

5 locations incl. Boston

Sponsor: Portal Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07567131·Recruiting

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Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)

for Congenital Heart Disease (CHD)

17 locations incl. Phoenix

Sponsor: Carelon Research

Sex: All·Age: 18+

Code: NCT07582861·Not Yet Recruiting

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

for Polycythemia Vera (PV)

5 locations incl. Denver

Sponsor: Prelude Therapeutics

Sex: All·Age: 18+

Code: NCT07469891·Phase 1·Recruiting

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A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma

Drug: PF-08634404

57 locations incl. Aurora

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07392892·Phase 2, Phase 3·Recruiting

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Window Study of Intratumoral Mitazalimab in Breast Cancer (WINIT-BC)

for Breast Cancer

1 location in Philadelphia

Sponsor: Jennifer Zhang

Sex: All·Age: 18+

Code: NCT07319195·EARLY_Phase 1·Recruiting

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Expectant Moms Managing Attention-Deficit/ Hyperactivity Disorder

for ADHD

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18+

Code: NCT07001293·Recruiting

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Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

51 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07195734·Phase 2·Recruiting

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Phase 2 Study to Assess the Safety and Efficacy of ANG003

for Exocrine Pancreatic Insufficiency (EPI)

26 locations incl. Long Beach

Sponsor: Anagram Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07450547·Phase 2·Recruiting

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Feasibility of The Health Integrated Nutrition and Kidney Wellness Program

for Chronic Kidney Disease

5 locations incl. Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07518719·Recruiting

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ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL

for CLL / SLL

4 locations incl. Bethesda

Sponsor: Newave Pharmaceutical Inc

Sex: All·Age: 18+

Code: NCT07342478·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2

for Narcolepsy Type 2

Drug: ALKS 2680

13 locations incl. Boulder

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT07502443·Phase 3·Recruiting

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Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs

for Diabetes in Adolescence

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT07216118·Recruiting

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Donidalorsen Treatment in Children With Hereditary Angioedema

for Hereditary Angioedema (HAE)

5 locations incl. Santa Monica

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 11

Code: NCT07298447·Phase 3·Recruiting

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GUCY2C Prime-Boost Vaccination for Advanced Colorectal and Small Bowel Adenocarcinomas

for Colorectal Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07417488·Phase 1·Recruiting

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A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

for Diabetic Macular Edema

Drug: RO7823653

8 locations incl. Peoria

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07425522·Phase 1·Recruiting

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A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

for KRAS-mutant Non-small Cell Lung Cancer (NSCLC)

7 locations incl. Sarasota

Sponsor: Kestrel Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07458347·Phase 1·Recruiting

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A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

for Crohn Disease

Drug: Risankizumab

17 locations incl. Dothan

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07499232·Phase 3·Recruiting

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AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

for Obesity

Drug: NNC0487-0111

13 locations incl. Anniston

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07503210·Phase 3·Recruiting

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Allergy Delabeling in Antibiotic Stewardship - Intervention

for Beta Lactam Allergy

1 location in Philadelphia

Sponsor: Ebbing Lautenbach

Sex: All·Age: 18+

Code: NCT07133074·Recruiting

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A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)

for Systemic Lupus Erythematosus

Drug: BI 3000202

31 locations incl. Beverly Hills

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 74

Code: NCT07409181·Phase 2·Recruiting

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Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic Pancreatitis

for Chronic Pancreatitis

2 locations incl. Baltimore

Sponsor: Anna Evans Phillips

Sex: All·Age: 18+

Code: NCT07418593·Phase 4·Recruiting

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Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

for Psoriatic Arthritis

Drug: Tulisokibart

15 locations incl. Sun City

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07486960·Phase 2·Recruiting

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In-Shoe Loadsol Force Analysis Study LC1 Fractures

for Geriatric Pelvic Ring Fractures

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 65+

Code: NCT07608107·Recruiting

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A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression

for Ovarian Cancer

11 locations incl. Phoenix

Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female·Age: 18+

Code: NCT07546500·Phase 3·Recruiting

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A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

for Dry Eye Disease (DED)

14 locations incl. Aliso Viejo

Sponsor: Oculis

Sex: All·Age: 18+

Code: NCT07548632·Phase 2, Phase 3·Recruiting

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Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention

for Sepsis

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 17

Code: NCT07084129·Phase 1·Recruiting

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A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late Onset Pompe Disease (PROGRESS-GT LOPD)

for Pompe Disease (Late-onset)

9 locations incl. Phoenix

Sponsor: AskBio Inc

Sex: All·Age: 18+

Code: NCT07282847·Phase 1, Phase 2·Recruiting

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A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for Macular Degeneration

9 locations incl. Mountain View

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07496567·Phase 2, Phase 3·Recruiting

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AYA-PeerConnect: A Communication Coaching Intervention for Adolescent/Young Adult Cancer Survivors (AYACS)

for Communication

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 35

Code: NCT07454460·Recruiting

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