Clinical Trials at Memorial Sloan Kettering Cancer Center

As of June 2026, 481 paid clinical trials are recruiting at Memorial Sloan Kettering Cancer Center, located at 1275 YORK AVE, MEMORIAL 7, NEW YORK, NY 10065-6007, phone (212) 639-2000 in New York, New York. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

481 clinical trials at Memorial Sloan Kettering Cancer Center

·Clear filters·↓ Download CSV

A Study of Stereotactic Radiosurgery (SRS) to Treat Pain in the Chest and/or Stomach Wall

for Thoracoabdominal Wall Pain

7 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05985148·Phase 1·Recruiting

Apply to this trial

Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

for cGVHD

32 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05919511·Recruiting

Apply to this trial

Lurbinectedin in FET-Fused Tumors

for Ewing Sarcoma

Drug: Lurbinectedin

6 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10+

Code: NCT05918640·Phase 1, Phase 2·Recruiting

Apply to this trial

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

for Myelofibrosis (PMF)

9 locations incl. Tampa

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT05835466·Phase 2·Recruiting

Apply to this trial

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

470 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting

Apply to this trial

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for Glioma

40 locations incl. Birmingham

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT05303519·Phase 3·Recruiting

Apply to this trial

A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer

for Improve Sexual Health

7 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05910294·Recruiting

Apply to this trial

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

for Refractory Ewing Sarcoma

Drug: Lurbinectedin

14 locations incl. Los Angeles

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 2 - 30

Code: NCT05734066·Phase 1, Phase 2·Recruiting

Apply to this trial

FOG-001 in Locally Advanced or Metastatic Solid Tumors

for Cancer

31 locations incl. Phoenix

Sponsor: Parabilis Medicines, Inc.

Sex: All·Age: 18+

Code: NCT05919264·Phase 1, Phase 2·Recruiting

Apply to this trial

Cord Blood Transplant in Adults With Blood Cancers

for Acute Myelogenous Leukemia (AML)

1 location in New York

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 21 - 65

Code: NCT05884333·Phase 2·Recruiting

Apply to this trial

Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

9 locations incl. Duarte

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting

Apply to this trial

Phase II Trial of Lung Chemoemobolization

for Lung Non-Small Cell Carcinoma

2 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672108·Phase 2·Recruiting

Apply to this trial

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Drug: Nivolumab

390 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting

Apply to this trial

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

for Anal Carcinoma

8 locations incl. La Jolla

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05663502·Recruiting

Apply to this trial

Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia

for T-Cell Large Granular Lymphocyte Leukemia

Drug: Ruxolitinib

3 locations incl. Boston

Sponsor: Jonathan Brammer

Sex: All·Age: 18+

Code: NCT05592015·Phase 2·Recruiting

Apply to this trial

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

for Recurrent Endometrial Carcinoma

Drug: Selumetinib

293 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05554328·Phase 2·Recruiting

Apply to this trial

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for Non-small Cell Lung Cancer

10 locations incl. Gilbert

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT05786924·Phase 1, Phase 2·Recruiting

Apply to this trial

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

28 locations incl. Los Angeles

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting

Apply to this trial

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

Apply to this trial

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

for Breast Cancer

10 locations incl. Birmingham

Sponsor: American College of Radiology

Sex: Female·Age: 45 - 74·Accepts healthy volunteers

Code: NCT05625659·Recruiting

Apply to this trial

A Study of Avutometinib (VS-6766) and Defactinib in People With Mesonephric Gynecologic Cancer

for Mesonephric Gynecologic Cancer

Drug: Avutometinib

7 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05787561·Phase 2·Recruiting

Apply to this trial

A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

for Primary Immune Regulatory Disorder

13 locations incl. San Francisco

Sponsor: Joseph Oved

Sex: All·Age: All ages

Code: NCT05787574·Phase 2·Recruiting

Apply to this trial

A Study of PYX-201 in Advanced Solid Tumors

for Solid Tumor

17 locations incl. Scottsdale

Sponsor: Pyxis Oncology, Inc

Sex: All·Age: 18+

Code: NCT05720117·Phase 1·Recruiting

Apply to this trial

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

150 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting

Apply to this trial

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

175 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

Apply to this trial

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

30 locations incl. Beverly Hills

Sponsor: Fore Biotherapeutics

Sex: All·Age: 10+

Code: NCT05503797·Phase 2·Recruiting

Apply to this trial

The Ambient Light Multiple Myeloma Study

for Multiple Myeloma

2 locations incl. New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 21+

Code: NCT05737732·Recruiting

Apply to this trial

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for Ovarian Cancer

4 locations incl. Baltimore

Sponsor: Imunon

Sex: Female·Age: 18+

Code: NCT05739981·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Collect Information About the Use of Redifferentiating Medications as a Standard Treatment for Thyroid Cancer

for Thyroid Cancer

1 location in New York

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05733013·Recruiting

Apply to this trial

Canakinumab for the Prevention of Progression to Cancer in Patients With Clonal Cytopenias of Unknown Significance, IMPACT Study

for Clonal Cytopenia of Undetermined Significance

Drug: Canakinumab

6 locations incl. Miami

Sponsor: Uma Borate

Sex: All·Age: 18+

Code: NCT05641831·Phase 2·Recruiting

Apply to this trial

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

for Relapsed/Refractory Multiple Myeloma

16 locations incl. Birmingham

Sponsor: Caribou Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05722418·Phase 1·Recruiting

Apply to this trial

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

Apply to this trial

Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations

for Prostate Cancer

6 locations incl. La Jolla

Sponsor: Rana McKay, MD

Sex: Male·Age: 18+

Code: NCT05498272·Phase 2·Recruiting

Apply to this trial

A Study of Ruxolitinib in Combination With Abemaciclib for the Treatment of Myelofibrosis

for Myelofibrosis Due to and Following Polycythemia Vera

Drug: Ruxolitinib

7 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05714072·Phase 1·Recruiting

Apply to this trial

A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2

for HER2-positive Breast Cancer

14 locations incl. Los Angeles

Sponsor: Mersana Therapeutics

Sex: All·Age: 18+

Code: NCT05514717·Phase 1·Recruiting

Apply to this trial

Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM)

for Colorectal Liver Metastases

5 locations incl. Miami

Sponsor: Society of Interventional Oncology

Sex: All·Age: 18+

Code: NCT05265169·Recruiting

Apply to this trial

A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer

for Endometrial Cancer

7 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05691010·EARLY_Phase 1·Recruiting

Apply to this trial

Metastatic Leiomyosarcoma Biomarker Protocol

for Leiomyosarcoma

9 locations incl. Santa Monica

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: All ages

Code: NCT05653388·Recruiting

Apply to this trial

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for Advanced Melanoma

Drug: Tebentafusp

25 locations incl. Phoenix

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT05549297·Phase 3·Recruiting

Apply to this trial

A Study of Daratumumab

for Multiple Myeloma

Drug: Daratumumab

7 locations incl. Miami

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: All ages

Code: NCT05438043·Phase 3·Recruiting

Apply to this trial