A Study of Stereotactic Radiosurgery (SRS) to Treat Pain in the Chest and/or Stomach Wall

Conditions

• Secondary to Parietal Pleura or Parietal Peritoneum Disease
• Thoracoabdominal Wall Pain

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Single-fraction stereotactic radiosurgery (SRS) — RADIATION
  Patients will be treated with single-fraction radiation therapy at three dose levels: 70 Gy, 80 Gy, and 90 Gy using image-guided SRS techniques.

Study Details

The researchers are doing this study to find out whether stereotactic radiosurgery (SRS) is a safe, practical (feasible), and effective treatment for people with chronic TAWP. The researchers will test different doses of SRS to find the highest dose that causes few or mild side effects.

Key Dates

Start date

Aug 2, 2023

Status verified

Jan 2026

Primary completion

Aug 31, 2028

Completion

Aug 31, 2028

Study Design

Enrollment

18 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Arms

• Experimental: Single-fraction stereotactic radiosurgery (SRS)
  Patients will be treated with single-fraction radiation therapy at three dose levels: 70 Gy, 80 Gy, and 90 Gy using image-guided SRS techniques.

Primary Outcome Measure

can be escalated from 70 Gy to 90 Gy without excessive DLTs [ Time Frame: 2 years ]

Central Contacts

• Josh Yamada, MD
  212-639-2950
  [email protected]
• Amitabh Gulati, MD
  212-639-6851

Locations (7)

Find similar trials in Basking Ridge, NJ