Paid Clinical Trials in Missouri

Missouri has 2,078 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,078 clinical trials

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Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

for Major Depressive Disorder

24 locations incl. Huntsville

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18 - 65

Code: NCT05850689·Phase 3·Recruiting

Apply to this trial

Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer

for Rectal Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 19+

Code: NCT04339374·Recruiting

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Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

for Thrombotic Microangiopathies

8 locations incl. San Diego

Sponsor: Omeros Corporation

Sex: All·Age: 28 Days - 17

Code: NCT05855083·Phase 2·Recruiting

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The Ailliance Post-Market Clinical Study

for Spinal Deformity

22 locations incl. Tucson

Sponsor: Medtronic Spinal and Biologics

Sex: All·Age: 18+

Code: NCT05856370·Recruiting

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Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

26 locations incl. Tucson

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting

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A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

for Metastatic Castration-resistant Prostate Neoplasms

Drug: Pasritamig

7 locations incl. Sarasota

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT05818683·Phase 1·Recruiting

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Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

for Recurrent Endometrial Carcinoma

Drug: Selumetinib

293 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05554328·Phase 2·Recruiting

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An Open-label Study of XEN1101 in Epilepsy

for Focal Epilepsy

53 locations incl. Phoenix

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT05718817·Phase 3·Enrolling By Invitation

A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

for Asthma

28 locations incl. Birmingham

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 - 17

Code: NCT05757102·Phase 3·Recruiting

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

59 locations incl. Birmingham

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting

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Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

11 locations incl. Los Angeles

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting

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Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for Non-small Cell Lung Cancer

20 locations incl. Gilbert

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT05786924·Phase 1, Phase 2·Recruiting

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

42 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting

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First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

28 locations incl. Los Angeles

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting

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Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

for Prostate Cancer

5 locations incl. Duarte

Sponsor: Varian, a Siemens Healthineers Company

Sex: Male·Age: 18+

Code: NCT05804318·Recruiting

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Efficacy of SynEx Wound Rinse in Civilian Surrogates of Combat Injury Wounds

for Wound Heal

2 locations incl. Washington D.C.

Sponsor: Synedgen, Inc.

Sex: All·Age: 18+

Code: NCT05743283·Recruiting

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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

for Neurotrophic Keratopathy

29 locations incl. Laguna Hills

Sponsor: ReGenTree, LLC

Sex: All·Age: 18+

Code: NCT05555589·Phase 3·Recruiting

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Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

for Pre-Bronchiolitis Obliterans Syndrome

20 locations incl. Phoenix

Sponsor: Renovion, Inc.

Sex: All·Age: 18 - 75

Code: NCT05654922·Phase 3·Recruiting

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

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A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

for Asthma

28 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 6 - 18

Code: NCT05692180·Phase 3·Recruiting

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A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS)

for Respiratory Distress Syndrome, Acute

11 locations incl. Washington D.C.

Sponsor: GEn1E Lifesciences

Sex: All·Age: 18 - 85

Code: NCT05795465·Phase 2·Recruiting

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Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

for Prediabetic State

40 locations incl. Phoenix

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT02915198·Phase 4·Recruiting

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Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

for Pediatric Brain Tumor

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 6 - 21

Code: NCT05521984·Phase 1·Recruiting

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Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

for Solid Tumor, Adult

4 locations incl. Detroit

Sponsor: Sairopa B.V.

Sex: All·Age: 18+

Code: NCT05856981·Phase 1·Recruiting

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Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans

for Nonalcoholic Steatohepatitis

1 location in Columbia

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05526144·Phase 2·Recruiting

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The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)

for Heart Failure

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 19 - 79

Code: NCT05562167·Phase 2·Recruiting

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A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

127 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05774951·Phase 3·Recruiting

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Digital vs. Speculum Exams for PPROM

for PPROM

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT05773014·Recruiting

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A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

for Hepatocellular Carcinoma

21 locations incl. Birmingham

Sponsor: Tvardi Therapeutics, Incorporated

Sex: All·Age: 18+

Code: NCT05440708·Phase 1, Phase 2·Recruiting

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A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for Geographic Atrophy

15 locations incl. Beverly Hills

Sponsor: Genentech, Inc.

Sex: All·Age: 50+

Code: NCT05626114·Phase 2·Recruiting

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Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for HIV Infection

11 locations incl. La Jolla

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 45 - 80

Code: NCT04949464·Recruiting

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Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for Lymphoma

45 locations incl. Tuscaloosa

Sponsor: University of Rochester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05006482·Phase 3·Recruiting

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CANF-Comb-II PET-MR in Atherosclerosis Multisite

for Carotid Atherosclerosis

2 locations incl. Los Angeles

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05838547·Recruiting

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Observational Study Protocol: LIVER-R

for Hepatobiliary Cancers

21 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06252753·Recruiting

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Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

for Infections

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: Female·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05846438·Recruiting

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Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

for Obesity

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT05219799·EARLY_Phase 1·Recruiting

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A Study of PYX-201 in Advanced Solid Tumors

for Solid Tumor

17 locations incl. Scottsdale

Sponsor: Pyxis Oncology, Inc

Sex: All·Age: 18+

Code: NCT05720117·Phase 1·Recruiting

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High Protein Diet and Atherosclerosis

for Atherosclerosis

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT05235464·Recruiting

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A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

for B-cell Lymphoma

4 locations incl. Westwood

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18+

Code: NCT05643742·Phase 1, Phase 2·Recruiting

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Disruptions of Brain Networks and Sleep by Electroconvulsive Therapy

for Treatment Resistant Depression

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 21 - 65

Code: NCT05905705·Recruiting

Apply to this trial