Paid Clinical Trials in Missouri

Missouri has 2,061 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,061 clinical trials

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Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

28 locations incl. Hot Springs

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07085767·Phase 3·Recruiting

Apply to this trial

Sleep Health in Pregnant Women in ENRICH

for Pregnancy

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 18+

Code: NCT07216287·Enrolling By Invitation

A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

for Smoking

Drug: Brenipatide

16 locations incl. Rogers

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07223840·Phase 2·Recruiting

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A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

31 locations incl. Phoenix

Sponsor: Bluefin Biomedicine, Inc.

Sex: All·Age: 18 - 75

Code: NCT07287644·Phase 2, Phase 3·Recruiting

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PET Imaging of MMP Activation in AAA: Clinical Component

for Abdominal Aortic Aneurysm

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07473102·EARLY_Phase 1·Recruiting

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CCM OPEN HF Registry

for Heart Failure

28 locations incl. Mesa

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT07112924·Recruiting

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7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

for Small-cell Lung Cancer

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT07175077·Recruiting

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Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma

for Glaucoma

1 location in Kansas City

Sponsor: Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07209410·Phase 4·Recruiting

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I-DECIDE After Bronchiolitis Hospitalization

for Bronchiolitis Acute

56 locations incl. Birmingham

Sponsor: Seattle Children's Hospital

Sex: All·Age: 0 Months - 24 Months

Code: NCT07243652·Recruiting

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Assessing the Neurological Outcomes After Atrial Fibrillation Ablation for Rhythm Control

for Atrial Fibrillation

7 locations incl. Overland Park

Sponsor: Kansas City Heart Rhythm Research Foundation

Sex: All·Age: 18+

Code: NCT06783868·Not Yet Recruiting

Enhanced Sternal Closure With Montage or Montage-CT to Evaluate Post-Operative Opioid Use Following Median Sternotomy

for Retrospective Review

2 locations incl. Naples

Sponsor: Abyrx, Inc.

Sex: All·Age: 19 - 80

Code: NCT07215546·Enrolling By Invitation

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

50 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting

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Neoadjuvant Zanzalintinib Plus Nivolumab in Patients With Locally Advanced and/or Inoperable Clear Cell Renal Cell Carcinoma With or Without Non-measurable Metastasis

for Locally Advanced Renal Cell Carcinoma

Drug: Nivolumab

3 locations incl. St Louis

Sponsor: Qian Qin

Sex: All·Age: 18+

Code: NCT06794229·Phase 2·Recruiting

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Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

for Pompe Disease

9 locations incl. Irvine

Sponsor: Shionogi

Sex: All·Age: 18+

Code: NCT07123155·Phase 2·Recruiting

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ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

for Breast Neoplasms

Drug: Pumitamig

26 locations incl. Springdale

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT07173751·Phase 3·Recruiting

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Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

for Geographic Atrophy (GA)

27 locations incl. Gilbert

Sponsor: ONL Therapeutics

Sex: All·Age: 55+

Code: NCT06659445·Phase 2·Recruiting

Apply to this trial

AI-driven Clinical Decision Support for Perioperative Blood Orders

for Surgery

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07223853·Recruiting

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Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery

for Unilateral Vocal Cord Paralysis

10 locations incl. La Jolla

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07579364·Enrolling By Invitation

Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

for Stage IV NSCLC

4 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06671613·Recruiting

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Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

for Breast Cancer

12 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18 - 99

Code: NCT07211178·Recruiting

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Clinical Trial of Vormatrigine in Adult Patients With Epilepsy

for Epilepsy, Tonic-Clonic

9 locations incl. Miami Lakes

Sponsor: Praxis Precision Medicines

Sex: All·Age: 18 - 85

Code: NCT07287163·Phase 3·Enrolling By Invitation

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Drug: Divarasib

50 locations incl. Anchorage

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06793215·Phase 3·Recruiting

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A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease

for Dry Eye Disease

32 locations incl. Phoenix

Sponsor: Bausch & Lomb Incorporated

Sex: All·Age: 18+

Code: NCT07128628·Phase 2·Recruiting

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A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

for Non-alcoholic Fatty Liver Disease

49 locations incl. Arcadia

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 75

Code: NCT07221227·Phase 3·Recruiting

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Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass

for Open Pilon Fractures

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT07227493·Recruiting

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A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

for Bone Cancer Metastatic

7 locations incl. San Diego

Sponsor: Society of Interventional Oncology

Sex: All·Age: 21+

Code: NCT06859801·Recruiting

Apply to this trial

Growth Hormone Resistance of Beta-cells A

for Gestational Diabetes

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06571487·Recruiting

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Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma

for Advanced Leiomyosarcoma

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06957431·Phase 1·Recruiting

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A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for Ovarian Neoplasms

20 locations incl. Newport Beach

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213791·Phase 1·Recruiting

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A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

for Ovarian Neoplasms

82 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

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Efficacy of Methylprednisolone for Pain Control After ACL Repair

for ACL Surgery

1 location in St Louis

Sponsor: St. Louis University

Sex: All·Age: 13 - 50

Code: NCT07158476·Phase 4·Recruiting

Apply to this trial

Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda

for HIV Prevention

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 15 - 24·Accepts healthy volunteers

Code: NCT07002866·Recruiting

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Proof of Concept Study to Assess the Pharmacokinetics/Pharmacodynamics of Nemolizumab in Adults With Chronic Pruritus of Unknown Origin (CPUO)

for Chronic Pruritus of Unknown Origin

Drug: Nemolizumab

25 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT07074977·Phase 2·Recruiting

Apply to this trial

Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer

for Uterine Cancer

4 locations incl. San Francisco

Sponsor: Washington University School of Medicine

Sex: Female·Age: 18+

Code: NCT06795009·Phase 1·Recruiting

Apply to this trial

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

for Clonal Mast Cell Disease

18 locations incl. Birmingham

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT07143669·Recruiting

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Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency

for Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)

3 locations incl. Walnut Creek

Sponsor: Pharvaris Netherlands B.V.

Sex: All·Age: 18+

Code: NCT07266805·Phase 3·Recruiting

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Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

376 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting

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A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

for Metabolic Dysfunction-Associated Steatotic Liver Disease

140 locations incl. Tuscaloosa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07165028·Phase 3·Recruiting

Apply to this trial

Lenvatinib 24 mg/Day Versus 10 mg/Day to Treat Symptomatic or Progressive Radioactive Iodine Resistant (RAIR) Differentiated Thyroid Cancer (DTC)

for Thyroid Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07092514·Phase 2·Recruiting

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A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

for Angelman Syndrome

8 locations incl. Los Angeles

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: 1 - 64

Code: NCT07157254·Phase 2·Recruiting

Apply to this trial