Paid Clinical Trials in Missouri

Missouri has 2,061 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,061 clinical trials

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A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin

for Diabetes Mellitus, Type 2

20 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT07215312·Phase 2·Recruiting

Apply to this trial

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

for PIK3CA-related Overgrowth Spectrum (PROS)

4 locations incl. St Louis

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 100

Code: NCT06997588·Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

for Mania

Drug: KarXT

20 locations incl. Bentonville

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07140913·Phase 3·Recruiting

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A Study of V118E in Healthy Participants (V118E-003)

for Healthy

4 locations incl. Hallandale

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 49·Accepts healthy volunteers

Code: NCT07168915·Phase 1·Recruiting

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A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)

for Arthritis, Rheumatoid

Drug: Tulisokibart

16 locations incl. Glendale

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07176390·Phase 2·Recruiting

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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis

Drug: Duvakitug

91 locations incl. Peoria

Sponsor: Sanofi

Sex: All·Age: 16 - 80

Code: NCT07184996·Phase 3·Recruiting

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Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

for Spinal Fusion

1 location in St Louis

Sponsor: Alexander T. Yahanda

Sex: All·Age: 18+

Code: NCT07218133·Recruiting

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Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

for High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements

83 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06649812·Phase 2·Recruiting

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for Muscle Invasive Bladder Urothelial Carcinoma

211 locations incl. Fort Smith

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT07097142·Phase 3·Recruiting

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A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for Breast Cancer

Drug: Giredestrant

16 locations incl. Duarte

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07100106·Phase 1, Phase 2·Recruiting

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Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

for Colorectal Adenomatous Polyp

5 locations incl. Ann Arbor

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05630794·Phase 1·Recruiting

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A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

for Non-obstructive Hypertrophic Cardiomyopathy

22 locations incl. La Jolla

Sponsor: Imbria Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07023614·Phase 2·Recruiting

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A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for Cachexia

Drug: ponsegromab

72 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06989437·Phase 2, Phase 3·Recruiting

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CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

for Transthyretin Amyloid Cardiomyopathy (ATTR CM)

Drug: Coramitug

61 locations incl. Phoenix

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07207811·Phase 3·Recruiting

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A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

4 locations incl. San Francisco

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80

Code: NCT06520098·Phase 2·Recruiting

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Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In

for NSCLC Stage IV

19 locations incl. Springdale

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18 - 90

Code: NCT06745908·Phase 3·Recruiting

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CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations

for Diabetic Foot Ulcer (DFU)

7 locations incl. Oxnard

Sponsor: Capsicure, LLC

Sex: All·Age: 18+

Code: NCT07046767·Recruiting

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Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

20 locations incl. Orange

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting

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Study of COYA 302 for the Treatment of ALS

for Amyotrophic Lateral Sclerosis (ALS)

21 locations incl. Phoenix

Sponsor: Coya Therapeutics

Sex: All·Age: 18 - 80

Code: NCT07161999·Phase 2·Recruiting

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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Duvakitug

93 locations incl. Peoria

Sponsor: Sanofi

Sex: All·Age: 16 - 80

Code: NCT07184931·Phase 3·Recruiting

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Multi-modal Imaging of Myofascial Pain - Phase 2

for Myofascial Pain

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT07322445·Recruiting

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Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction

for Atrial Fibrillation

9 locations incl. Loma Linda

Sponsor: Kansas City Heart Rhythm Research Foundation

Sex: All·Age: 21 - 90

Code: NCT05464940·Not Yet Recruiting

Clinical Course Of Disease In Participants With FA-CM

for Friedreich Ataxia

8 locations incl. La Jolla

Sponsor: Lexeo Therapeutics

Sex: All·Age: 6+

Code: NCT06865482·Recruiting

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Improvement of an Algorithm to Detect Structural Heart Murmurs in Adult Patients Using Electronic Stethoscopes

for Structural Heart Disease

1 location in Springfield

Sponsor: Eko Devices, Inc.

Sex: All·Age: 18+

Code: NCT07202104·Recruiting

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Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder

for Bipolar I or II Disorder

47 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT07220460·Phase 2·Recruiting

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RELIVE (Randomized Evaluation of Less Invasive Ventricular Enhancement) Trial

for Left Ventricle Remodeling

6 locations incl. Phoenix

Sponsor: BioVentrix

Sex: All·Age: 18+

Code: NCT06813820·Recruiting

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A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)

for Colon Cancer

14 locations incl. Denver

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT07011576·Phase 2·Recruiting

Apply to this trial

Compass 3: A Novel Transition Program to Reduce Disability After Stroke

for Stroke

2 locations incl. Columbia

Sponsor: Washington University School of Medicine

Sex: All·Age: 55+

Code: NCT07069660·Recruiting

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A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

for Non-small Cell Carcinoma

133 locations incl. Alabaster

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07144280·Phase 3·Recruiting

Apply to this trial

TLN-372 in Advanced KRAS Mutant Solid Tumors

for KRAS Mutant Solid Tumors

6 locations incl. Birmingham

Sponsor: Treeline Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07204340·Phase 1·Recruiting

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Effect of Ketone Esters on Liver Fat Content and Metabolic Function

for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT07097506·Phase 2·Recruiting

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Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

for Urothelial Cancer

38 locations incl. Fullerton

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07129993·Phase 2, Phase 3·Recruiting

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A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

for Radiographic Axial Spondyloarthritis

Drug: Tulisokibart

33 locations incl. Chandler

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07133633·Phase 2·Recruiting

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A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza

for Influenza

120 locations incl. Anniston

Sponsor: Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Sex: All·Age: 12+

Code: NCT07159763·Phase 3·Recruiting

Apply to this trial

Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study

for Heavy Menstrual Bleeding

9 locations incl. Palo Alto

Sponsor: Oregon Health and Science University

Sex: Female·Age: 10 - 24

Code: NCT05916469·Recruiting

Apply to this trial

Transcutaneous Auricular Vagus Enhanced Recovery in the NeuroICU

for Acute Neurological Injury

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07219108·Recruiting

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A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for Breast Cancer

14 locations incl. Orlando

Sponsor: Terremoto Biosciences Inc.

Sex: All·Age: 18+

Code: NCT07109726·Phase 1, Phase 2·Recruiting

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A Study of PHN-012 in Patients With Advanced Solid Tumors

for Colon Cancer

11 locations incl. Los Angeles

Sponsor: Pheon Therapeutics

Sex: All·Age: 18+

Code: NCT07127874·Phase 1·Recruiting

Apply to this trial

GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

for Aortic Dissection

16 locations incl. Birmingham

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06827990·Recruiting

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Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

for Plaque Psoriasis

Drug: Deucravacitinib

122 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40+

Code: NCT07116967·Phase 3·Recruiting

Apply to this trial