Multi-modal Imaging of Myofascial Pain - Phase 2

Part of paid clinical trials in St Louis, Missouri.

Sponsor
Washington University School of Medicine
Study ID
NCT07322445
Status
Recruiting
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Conditions

  • Myofascial Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • 50/50 Mixture of Lidocaine 1% injection + Bupivacaine 0.25% Injectable Solution — DRUG
    Treatment Group: Receives trigger-point injection with a 50/50 mixture of 1% lidocaine and 0.25% bupivacaine
  • Dry Needling — PROCEDURE
    Single session of dry needling to the identified trigger point(s) per protocol.

Study Details

The goal of this study is to evaluate imaging biomarkers for quantitative assessments of myofascial pain and determine their ability to monitor treatment response and predict clinical outcomes.

Key Dates

Start date
Oct 1, 2025
Status verified
Jan 2026
Primary completion
Aug 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Chemical Injection
    Local chemical injection at clinician-identified myofascial trigger points.
  • Placebo Comparator: Dry Needle
    Dry needling at clinician-identified myofascial trigger points.

Primary Outcome Measure

Statistical Plan [ Time Frame: Baseline and follow-up study visits approximately 2 weeks apart (each visit lasting 3-4 hours) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Washington UniversitySt LouisMissouri63110
Andre Guthrie, BS
[email protected]
3142732556
Yong Wang, PhD (PRINCIPAL_INVESTIGATOR)
Song Hu, PhD (PRINCIPAL_INVESTIGATOR)

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Washington University· St Louis, MO

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