Paid Clinical Trials in Missouri

Missouri has 2,061 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,061 clinical trials

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A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

for Squamous Cell Carcinoma of Head and Neck

Drug: Amivantamab

41 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07276399·Phase 3·Recruiting

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A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for Locally Advanced Urothelial Carcinoma

148 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06524544·Phase 3·Recruiting

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SGLT2 Inhibitors in Geographic Atrophy

for Retinal Degeneration

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 50+

Code: NCT07174687·Phase 2·Recruiting

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Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for Castration-Sensitive Prostate Carcinoma

Drug: Apalutamide

194 locations incl. Tucson

Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male·Age: 18+

Code: NCT06931340·Phase 3·Recruiting

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Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

for Carcinoma, Hepatocellular

Drug: PF-08634404

22 locations incl. Land O' Lakes

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07227012·Phase 1, Phase 2·Recruiting

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First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for Esophageal Squamous Cell Carcinoma

10 locations incl. Scottsdale

Sponsor: Plexium, Inc.

Sex: All·Age: 18+

Code: NCT07284186·Phase 1·Recruiting

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An Efficacy and Safety Study of DFL24498 in the Treatment of AKC

for Atopic Keratoconjunctivitis

8 locations incl. Jacksonville

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 18 - 65

Code: NCT07395232·Phase 3·Recruiting

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A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

for Small-cell Lung Cancer

28 locations incl. Aurora

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07218146·Phase 3·Recruiting

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Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Upper Extremities

for Actinic Keratosis

20 locations incl. Phoenix

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144852·Phase 3·Recruiting

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Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

for Endometrial Cancer

43 locations incl. Washington D.C.

Sponsor: Genmab

Sex: Female·Age: 18+

Code: NCT07166094·Phase 3·Recruiting

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A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

for Acromegaly

9 locations incl. Los Angeles

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06930625·Phase 3·Recruiting

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Observational Study of VYKAT™ XR in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

15 locations incl. Los Angeles

Sponsor: Soleno Therapeutics, Inc.

Sex: All·Age: 4+

Code: NCT07450664·Enrolling By Invitation

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

for Muscle Invasive Bladder Urothelial Carcinoma

143 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061964·Phase 2·Recruiting

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SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes

for Type 1 Diabetes

23 locations incl. San Francisco

Sponsor: SAb Biotherapeutics, Inc.

Sex: All·Age: 5 - 40

Code: NCT07187531·Phase 2·Recruiting

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Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

for Chronic Spontaneous Urticaria

19 locations incl. Birmingham

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07256392·Phase 3·Enrolling By Invitation

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for Parkinson's Disease

Drug: Prasinezumab

42 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 85

Code: NCT07174310·Phase 3·Recruiting

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A Digital Intervention to Decrease Self-Stigma Among Pregnant and Postpartum Women With Substance Use Disorder

for Substance Use Disorder

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 18+

Code: NCT07211867·Recruiting

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A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for Epithelial Ovarian Cancer

64 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06890338·Phase 2·Recruiting

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Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

75 locations incl. Birmingham

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT07231419·Phase 3·Recruiting

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Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp

for Actinic Keratosis

10 locations incl. Fremont

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144345·Phase 3·Recruiting

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A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: 6 Months - 17

Code: NCT07188805·Phase 3·Recruiting

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A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for Advanced or Metastatic Solid Tumors

15 locations incl. Santa Monica

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07205718·Phase 1, Phase 2·Recruiting

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Endovascular Repair With Fenestrated TREO Stent-Graft System in AAA

for Abdominal Aortic Aneurysms (AAA)

7 locations incl. Colorado Springs

Sponsor: Bolton Medical

Sex: All·Age: 18+

Code: NCT07026877·Recruiting

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This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment

for Atopic Dermatitis

43 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT07290803·Recruiting

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Trial of Neoadjuvant THP vs TCHP for HER2-Amplified/Positive Breast Cancer

for Breast Cancer

8 locations incl. Fairway

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18+

Code: NCT07220135·Phase 2·Recruiting

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ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for Major Depressive Disorder (MDD)

21 locations incl. Birmingham

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07284667·Phase 2·Recruiting

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A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

for Idiopathic Pulmonary Fibrosis

Drug: BI 765423

15 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07036523·Phase 2·Recruiting

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A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

42 locations incl. Mobile

Sponsor: Incyte Corporation

Sex: Female·Age: 18 - 99

Code: NCT07023627·Phase 2·Recruiting

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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for BRAF V600 Mutation

Drug: Dabrafenib

6 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 25

Code: NCT07110246·Phase 2·Recruiting

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

148 locations incl. Loma Linda

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting

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Early Feasibility Study of Cartilage Defect Repair

for Osteoarthritis, Hip

1 location in St Louis

Sponsor: Cytex Therapeutics, Inc.

Sex: All·Age: 14 - 64

Code: NCT06823089·Recruiting

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Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma

for Glioblastoma

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06831526·EARLY_Phase 1·Recruiting

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A Phase 1 Clinical Trial of Siltuximab for the Treatment of Antibody-Mediated Rejection After Lung Transplantation

for Antibody Mediated Rejection of Lung Transplant

2 locations incl. St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06990711·Phase 1·Recruiting

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A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

for Lymphoma

14 locations incl. Aurora

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT07015242·Phase 2·Recruiting

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A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

for Bronchiectasis With Pseudomonas Aeruginosa Colonization

25 locations incl. Orange

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07088926·Phase 2·Recruiting

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Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for Neovascular Age-related Macular Degeneration

Drug: Surabgene Lomparvovec

53 locations incl. Mesa

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT07007065·Phase 3·Recruiting

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

260 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting

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Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for Non-Small Cell Lung Cancer

28 locations incl. Irvine

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07100080·Phase 2, Phase 3·Recruiting

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A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart

21 locations incl. Little Rock

Sponsor: Vasa Therapeutics

Sex: All·Age: 50+

Code: NCT07219511·Phase 1·Recruiting

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Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Ruxolitinib

24 locations incl. Phoenix

Sponsor: Incyte Corporation

Sex: All·Age: 12 - 75

Code: NCT07049575·Phase 1·Recruiting

Apply to this trial