A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy
Part of paid clinical trials in San Diego, California.
- Sponsor
- Society of Interventional Oncology
- Study ID
- NCT06859801
- Status
- Recruiting
Conditions
- Bone Cancer Metastatic
Eligibility Criteria
- Sex
- ALL
- Age
- 21 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Percutaneous Ablation — DEVICEPercutaneous ablation is a minimally invasive alternative therapy for metastatic bone disease and can be used for destruction of nerves mediating pain signals, tumor destruction, decompression, or inhibition of tumor growth.
- Radiation Therapy — RADIATIONRadiation therapy (RT) is a widely accepted treatment for painful bone metastases and provides palliation of pain for patients.
Study Details
The objective of this study is to evaluate real-world outcomes (e.g., pain, patient reported outcomes, skeletal related events, healthcare utilization, etc.) in patients treated with both percutaneous ablation and palliative radiation therapy (RT).
Key Dates
- Start date
- Oct 23, 2025
- Status verified
- Jun 2026
- Primary completion
- Jul 31, 2027
- Completion
- Jul 31, 2027
Study Design
- Enrollment
- 120 participants (estimated)
Primary Outcome Measure
Pain Response [ Time Frame: 3 Months ]
Locations (7)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of California San Diego Moores Cancer Center | San Diego | California | 92093 | Anthony Tadros, MD (PRINCIPAL_INVESTIGATOR) Kathryn Tringale, MD (PRINCIPAL_INVESTIGATOR) |
| Baptist Health Medical Group | Miami | Florida | 33176 | Gina Landinez, MD (PRINCIPAL_INVESTIGATOR) Jean Pierre Obeid, MD (PRINCIPAL_INVESTIGATOR) |
| Emory University Hospital | Atlanta | Georgia | 30322 | Junjian Huang, MD (PRINCIPAL_INVESTIGATOR) Rohini Bhatia, MD (PRINCIPAL_INVESTIGATOR) |
| Northside Hospital | Atlanta | Georgia | 30342 | Jason Levy, MD (PRINCIPAL_INVESTIGATOR) Mudit Chowdhary, MD (PRINCIPAL_INVESTIGATOR) |
| Mayo Clinic | Rochester | Minnesota | 55905 | Brian Welch, MD (PRINCIPAL_INVESTIGATOR) Sean Park, MD (PRINCIPAL_INVESTIGATOR) |
| Washington University | St Louis | Missouri | 63110 | Resten Imaoka, MD (PRINCIPAL_INVESTIGATOR) Joanna Yang, MD (PRINCIPAL_INVESTIGATOR) |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Matthew Scheidt, MD (PRINCIPAL_INVESTIGATOR) Meena Bedi, MD (PRINCIPAL_INVESTIGATOR) |