Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

Part of paid clinical trials in Long Beach, California.

Sponsor
VA Office of Research and Development
Study ID
NCT06671613
Status
Recruiting
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Conditions

  • Fasting Mimicking Diet
  • Immunotherapy
  • NSCLC
  • Stage IV NSCLC

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • FMD — DIETARY_SUPPLEMENT
    Plant-based diet program
  • Regular Diet Plus FMD — COMBINATION_PRODUCT
    Patients will eat a RD with the first 3 cycles, then receive 3 cycles of FMD as they continue cycles 4-6

Study Details

The purpose of this study is to learn the effects of fasting on cancer cells while you get maintenance treatment.

Key Dates

Start date
Oct 27, 2025
Status verified
Nov 2025
Primary completion
Dec 31, 2029
Completion
Dec 31, 2030

Study Design

Enrollment
66 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE

Arms

  • Active Comparator: Regular Diet
    Patients will eat a RD with the first 3 cycles, then receive 3 cycles of FMD as they continue cycles 4-6.
  • Experimental: FMD
    Plant based diet program.

Primary Outcome Measure

Feasibility of fasting mimicking diet intervention [ Time Frame: Through study completion up to 2 years. ]

Central Contacts

Locations (4)

FacilityCityStateZIPSite coordinators
VA Long Beach Healthcare System, Long Beach, CALong BeachCalifornia90822
Pankaj Gupta, MD
[email protected]
562-826-8000
Neha Shah, PhD
[email protected]
5628268000
Jesse Brown VA Medical Center, Chicago, ILChicagoIllinois60612
Larry Feldman, MD
[email protected]
312-569-5385
Cindy Chan
[email protected]
3129987962
Richard L. Roudebush VA Medical Center, Indianapolis, INIndianapolisIndiana46202-2884
Shadia Jalal, MD
[email protected]
(317) 274-5500
Aleksandra Radovanovich, RN
[email protected]
(317) 988-3338
Shadia Jalal, MD (PRINCIPAL_INVESTIGATOR)
St. Louis VA Medical Center John Cochran Division, St. Louis, MOSt LouisMissouri63106-1621
Theodore Thomas, MD
[email protected]
314-652-4100
Carla Prost
[email protected]
3148143231

Find similar trials in Long Beach, CA

By condition
Lung cancer
By specialty
OncologyLung oncologyLung disease
By research site
VA Long Beach Healthcare System, Long Beach, CA· Long Beach, CAJesse Brown VA Medical Center, Chicago, IL· Chicago, ILRichard L. Roudebush VA Medical Center, Indianapolis, IN· Indianapolis, INSt. Louis VA Medical Center John Cochran Division, St. Louis, MO· St Louis, MO

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