Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

for Cardiovascular Diseases

5 locations incl. Boston

Sponsor: Fundación EPIC

Sex: All·Age: 18 - 85

Code: NCT07286578·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

for Aortic Aneurysm

16 locations incl. Los Angeles

Sponsor: Vascutek Ltd.

Sex: All·Age: 18+

Code: NCT07078383·Recruiting

Apply to this trial

Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis

for Osteoarthritis Hand

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 50+

Code: NCT07217405·Phase 4·Recruiting

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A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostatic Neoplasms, Castration-Resistant

Drug: Pasritamig

49 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07225946·Phase 3·Recruiting

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NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease

for Graves Disease

8 locations incl. Phoenix

Sponsor: Merida Biosciences

Sex: All·Age: 18 - 55

Code: NCT07305818·Phase 1·Recruiting

Apply to this trial

Just-in-Time Training for Youth Mentors

for Mental Health Issue

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT07129070·Recruiting

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Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for Non-small Cell Lung Cancer

70 locations incl. Phoenix

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06686771·Phase 3·Recruiting

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The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.

for Metastatic Solid Tumors

1 location in Rochester

Sponsor: New Phase Ltd.

Sex: All·Age: 18+

Code: NCT07224464·Recruiting

Apply to this trial

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

for Focal Epilepsy

7 locations incl. Boise

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT07219407·Phase 2·Recruiting

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Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)

for Blood Pressure

5 locations incl. Birmingham

Sponsor: Biobeat Technologies Ltd.

Sex: All·Age: 18+

Code: NCT07240831·Recruiting

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The Effect of Cosmetic Formulations on the Appearance of Grey Hair.

for Hair Graying

1 location in Minneapolis

Sponsor: Unilever R&D

Sex: All·Age: 25 - 60

Code: NCT07280676·Recruiting

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A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

17 locations incl. Birmingham

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting

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Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

for Turner Syndrome

9 locations incl. Sacramento

Sponsor: Ascendis Pharma A/S

Sex: All·Age: 2 - 17

Code: NCT07221851·Phase 3·Recruiting

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One vs. Two Stents for Gallbladder Disease

for Recurrent Cholecystitis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 95

Code: NCT07222527·Recruiting

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BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma

for Metastatic Pancreatic Adenocarcinoma

Drug: Nivolumab

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07226856·Phase 2·Recruiting

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Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

for Advanced Or Metastatic Merkel Cell Carcinoma

18 locations incl. Los Angeles

Sponsor: TuHURA Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT06947928·Phase 2, Phase 3·Recruiting

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A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia

for Congenital Adrenal Hyperplasia

9 locations incl. Los Angeles

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07144163·Phase 3·Recruiting

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Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for Intestinal Neoplasms

Drug: PF-08634404

150 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07222800·Phase 3·Recruiting

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Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia

for Fibromyalgia

6 locations incl. Ann Arbor

Sponsor: SPIRE Therapeutics Inc.

Sex: All·Age: 22+

Code: NCT07226648·Recruiting

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Efficacy and Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome

for Short Bowel Syndrome (SBS)

4 locations incl. Rochester

Sponsor: Zealand Pharma

Sex: All·Age: 18+

Code: NCT07228403·Phase 3·Enrolling By Invitation

Minimal Sedation During Knee Replacement Surgery

for Total Knee Arthroplasty

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07371390·Recruiting

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A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

for Major Depressive Disorder (MDD)

32 locations incl. Birmingham

Sponsor: Cybin IRL Limited

Sex: All·Age: 18 - 85

Code: NCT06793397·Phase 3·Recruiting

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ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

for Breast Cancer, Metastatic

21 locations incl. Tucson

Sponsor: ALX Oncology Inc.

Sex: All·Age: 18+

Code: NCT07007559·Phase 2·Recruiting

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Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for Miscellaneous Neoplasm, Nos

231 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07091617·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

8 locations incl. Springdale

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07155187·Phase 2, Phase 3·Recruiting

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Studying Quality of Life Inclusive of Mental Health and Cognitive Behavioral Therapy for Cancer Distress for the Improvement of Quality of Life in Stage III-IV Melanoma Patients

for Melanoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07379138·Recruiting

Apply to this trial

Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)

for High Grade Neuroendocrine Neoplasms

2 locations incl. Rochester

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06926634·Phase 2·Recruiting

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A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

for Chronic Kidney Disease

Drug: Empagliflozin

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07107945·Phase 3·Recruiting

Apply to this trial

Phase 1 Study of CLR 125 in Triple Negative Breast Cancer

for Breast Cancer

4 locations incl. Jacksonville

Sponsor: Cellectar Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07311993·Phase 1·Recruiting

Apply to this trial

A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

for Biliary Tract Cancer

Drug: Rilvegostomig

33 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07221253·Phase 3·Recruiting

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Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for the Treatment of Patients With Gastric and Gastroesophageal Junction Adenocarcinoma at High Risk of Peritoneal Recurrence

for Clinical Stage I Gastric Cancer AJCC v8

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT07139951·Phase 2·Enrolling By Invitation

Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years

for Fuchs Endothelial Corneal Dystrophy

14 locations incl. Atlanta

Sponsor: Case Western Reserve University

Sex: All·Age: 30 - 93

Code: NCT07217249·Enrolling By Invitation

A Study Of MCG In Cardiac Amyloidosis

for Amyloidosis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07218705·Recruiting

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A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

for Gastrointestinal Neoplasms

35 locations incl. Phoenix

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07218926·Phase 3·Recruiting

Apply to this trial

A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke

for Ischemic Stroke

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07291024·Recruiting

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A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for Locally Advanced Urothelial Carcinoma

148 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06524544·Phase 3·Recruiting

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A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

for Alzheimer Disease

Drug: KarXT

48 locations incl. Chandler

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT06937229·Phase 3·Recruiting

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Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for Castration-Sensitive Prostate Carcinoma

Drug: Apalutamide

194 locations incl. Tucson

Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male·Age: 18+

Code: NCT06931340·Phase 3·Recruiting

Apply to this trial

Radiofrequency Ablation/Bone Augmentation + Radiotherapy vs Radiotherapy Alone

for Spine Metastases

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07090122·Recruiting

Apply to this trial

A ELN-Multicenter Study on Phenotypic Evolution and Clinical Outcomes

for Polycythemia Vera

1 location in Rochester

Sponsor: FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS

Sex: All·Age: 18 - 100

Code: NCT07203768·Recruiting

Apply to this trial