A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT07291024
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Vagus nerve stimulation (VNS) paired with mobility training — OTHER
    Participants will complete a 6-week in-clinic therapy phase (3 sessions per week), where a physical therapist will lead mobility training with VNS delivered via a handheld magnet. This will be followed by a 6-week at-home phase where participants continue daily exercises and VNS use, supported by weekly video calls to review at home rehabilitation activity and wearable activity monitors for remote monitoring.

Study Details

The purpose of this study is to evaluate the safety, feasibility, and efficacy of vagus nerve stimulation (VNS) paired with mobility training to improve lower extremity function and gait in individuals with chronic ischemic stroke.

Key Dates

Start date
Dec 3, 2025
Status verified
Feb 2026
Primary completion
Jan 1, 2029
Completion
Jan 1, 2029

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Chronic ischemic stroke
    Participants with chronic ischemic stroke will be treated with a combination of vagus nerve stimulation and mobility training.

Primary Outcome Measure

Number of serious adverse events related to vagus nerve stimulation or therapy [ Time Frame: 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905
Neurosurgery Research Team
507-293-1283
Rushna Ali, MD (PRINCIPAL_INVESTIGATOR)
Muhib Khan, MD, MBBS (PRINCIPAL_INVESTIGATOR)

Find similar trials in Rochester, MN

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Mayo Clinic in Rochester· Rochester, MN

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