Paid Clinical Trials in Massachusetts

Massachusetts has 3,602 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,602 clinical trials

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Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

for Metastatic Malignant Solid Neoplasm

7 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04585958·Phase 1·Recruiting

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Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE

for Eosinophilic Esophagitis

25 locations incl. Scottsdale

Sponsor: Dr. Falk Pharma GmbH

Sex: All·Age: 18 - 75

Code: NCT06596252·Phase 3·Recruiting

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Mind Body Syndrome Therapy for Chronic Pain

for Chronic Pain

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18 - 67

Code: NCT04689646·Recruiting

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Sacituzumab Govitecan Plus EV in Metastatic UC

for Urothelial Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04724018·Phase 1, Phase 2·Recruiting

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A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

for Acute Leukemia

26 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2+

Code: NCT04811560·Phase 1, Phase 2·Recruiting

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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

for Pulmonary Arterial Hypertension

28 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07218029·Phase 3·Recruiting

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Right-Size Clinic Visits Using Memora Platform for PROMIS

for Orthopedic Disorders

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT04441567·Recruiting

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Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

for Locally Advanced (Inoperable) or Metastatic Breast Cancer

54 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT04862663·Phase 3·Recruiting

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Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for Metastatic Non Small Cell Lung Cancer

46 locations incl. Gilbert

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT04614103·Phase 2·Recruiting

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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

for Post Operative Surgical Site Infection

31 locations incl. Redwood City

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting

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Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

for Symptomatic Hypertrophic Cardiomyopathy (HCM)

Drug: Aficamten

52 locations incl. Birmingham

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT04848506·Phase 2, Phase 3·Enrolling By Invitation

CONFIRM: Magnetic Resonance Guided Radiation Therapy

for Gastric Cancer

2 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT04368702·Recruiting

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A Multi-Center Diagnostic Stewardship Program to Improve Respiratory Culture Utilization in Critically Ill Children

for Ventilator Associated Pneumonia

8 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: All ages

Code: NCT04987840·Enrolling By Invitation

Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

17 locations incl. Los Angeles

Sponsor: Debiopharm International SA

Sex: All·Age: 12+

Code: NCT04855656·Phase 1·Recruiting

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An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus

for Tinnitus

1 location in Boston

Sponsor: D. Bradley Welling, MD, PhD

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04192773·EARLY_Phase 1·Recruiting

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Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

for Acute Treatment of Migraine

Drug: Rimegepant

116 locations incl. Scottsdale

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT04743141·Phase 3·Recruiting

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CorEvitas SPHERES (Synergy of Prospective Health & Experimental Research for Emerging Solutions) Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)

for Neuromyelitis Optica Spectrum Disorder

1 location in Waltham

Sponsor: CorEvitas

Sex: All·Age: 18+

Code: NCT04886492·Enrolling By Invitation

Pediatric Delirium

for Pediatric Delirium

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 3 Months - 9·Accepts healthy volunteers

Code: NCT04669457·Phase 4·Enrolling By Invitation

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for Recurrent Head and Neck Squamous Cell Carcinoma

178 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 79

Code: NCT04671667·Phase 2·Recruiting

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ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

for Acute Hepatic Porphyria

13 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 12+

Code: NCT04883905·Recruiting

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Neural Correlates of Stress and Perceived Control in Adolescent Depression

for Major Depressive Disorder

1 location in Belmont

Sponsor: Mclean Hospital

Sex: Female·Age: 14 - 18·Accepts healthy volunteers

Code: NCT04788524·Recruiting

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Vaginal Microbiota Transplant

for Recurrent Bacterial Vaginosis

1 location in Boston

Sponsor: Douglas Kwon

Sex: Female·Age: 18 - 50

Code: NCT04046900·Phase 1, Phase 2·Recruiting

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Childhood Cancer Predisposition Study (CCPS)

for Pediatric Cancer

6 locations incl. Atlanta

Sponsor: Emory University

Sex: All·Age: All ages

Code: NCT04511806·Recruiting

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

49 locations incl. Birmingham

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

for Low-grade Glioma

14 locations incl. San Francisco

Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All·Age: 6 Months - 25

Code: NCT04775485·Phase 2·Recruiting

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Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for Langerhan's Cell Histiocytosis

12 locations incl. Phoenix

Sponsor: Carl Allen

Sex: All·Age: All ages

Code: NCT04079179·Phase 2·Recruiting

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Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

for Chronic Pain

1 location in Charlestown

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 80

Code: NCT04206215·Recruiting

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A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study

for Ovarian Neoplasms

Drug: Niraparib

13 locations incl. Tucson

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT04641247·Phase 2·Recruiting

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Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

for Propionic Acidemia

15 locations incl. Los Angeles

Sponsor: ModernaTX, Inc.

Sex: All·Age: All ages

Code: NCT04159103·Phase 1, Phase 2·Recruiting

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Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

for Primary Hyperoxaluria Type 1

4 locations incl. San Francisco

Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Sex: All·Age: All ages

Code: NCT04580420·Phase 2·Recruiting

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A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for High Grade Glioma

10 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04655404·EARLY_Phase 1·Recruiting

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Optimization of NIBS for Treatment of Addiction

for Opioid-use Disorder

3 locations incl. Hinsdale

Sponsor: Case Western Reserve University

Sex: All·Age: 18 - 85

Code: NCT04379115·Recruiting

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Computational Neuroscience of Language Processing in the Human Brain

for Language

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 85

Code: NCT05222594·Recruiting

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Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event

for Brief Resolved Unexplained Event

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 Months - 12 Months

Code: NCT04477460·Recruiting

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Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

for Dysphagia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04504227·Recruiting

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

22 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting

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Intermuscular Coherence as a Biomarker for ALS

for Amyotrophic Lateral Sclerosis

4 locations incl. Irvine

Sponsor: University of Chicago

Sex: All·Age: 20 - 90·Accepts healthy volunteers

Code: NCT05104710·Recruiting

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Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

for Peripheral Vascular Diseases

52 locations incl. Jonesboro

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT04674969·Recruiting

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A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

12 locations incl. Duarte

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT04786262·Phase 3·Recruiting

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Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

for Kidney Disease, End-Stage

16 locations incl. La Jolla

Sponsor: C. R. Bard

Sex: All·Age: 18+

Code: NCT04634916·Recruiting

Apply to this trial