Childhood Cancer Predisposition Study (CCPS)

Part of paid clinical trials in Atlanta, Georgia.

Sponsor
Emory University
Study ID
NCT04511806
Status
Recruiting
Apply to this trial

Conditions

  • Pediatric Cancer

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • Registry — OTHER
    This prospective registry and biorepository will collect clinical data and specimens for research in childhood cancer predisposition.

Study Details

The Childhood Cancer Predisposition Study (CCPS) is a multi-center, longitudinal, observational study that will collect clinical and biological data and specimens from children with a cancer predisposition syndromes (CPS) and their relatives. The central hypothesis is that studying individuals at high risk for childhood cancer creates a unique opportunity for improving the understanding of carcinogenesis, tumor surveillance, early detection, and cancer prevention, which will collectively contribute to improving care and outcomes for pediatric patients with cancer and those with cancer predisposition syndromes (CPS).

Key Dates

Start date
Apr 22, 2021
Status verified
Oct 2025
Primary completion
Oct 31, 2030
Completion
Oct 31, 2030

Study Design

Enrollment
1,050 participants (estimated)

Arms

  • Arm: Primary Subjects
    Children (age 0-21) with a cancer predisposition syndromes (CPS).
  • Arm: Relatives of Children with CPS
    Members of their Primary Family Unit will also be recruited for this study, including CPS-Affected Parents, Unaffected Parents and Siblings. Other adult family members (with documented or obligate CPS) are also eligible to enroll as Affected Family Members.

Primary Outcome Measure

Establish and maintain a framework for recruitment, participation, and surveillance of children with cancer predisposition syndromes (CPS) in clinical and translational research studies. [ Time Frame: Up to 10 years ]

Central Contacts

Locations (6)

FacilityCityStateZIPSite coordinators
Children's Healthcare of Atlanta (CHOA)AtlantaGeorgia30322
Christopher Porter, MD
[email protected]
404-727-4881
Dana Farber Cancer InstituteBostonMassachusetts02215
Lisa Diller, MD
[email protected]
Children's Hospital of PhiladelphiaPhiladelphiaPennsylvania19104
Garrett Brodeur, MD
[email protected]
St. Jude Children's Research HospitalMemphisTennessee38105-3678
Kim Nichols, MD
[email protected]
Baylor College of MedicineHoustonTexas77030
Surya Rednam, MD
[email protected]
Primary Children's HospitalSalt Lake CityUtah84113
Joshua Schiffman, MD
[email protected]

Find similar trials in Atlanta, GA

By research site
Children's Healthcare of Atlanta (CHOA)· Atlanta, GADana Farber Cancer Institute· Boston, MAChildren's Hospital of Philadelphia· Philadelphia, PASt. Jude Children's Research Hospital· Memphis, TNBaylor College of Medicine· Houston, TXPrimary Children's Hospital· Salt Lake City, UT

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