CONFIRM: Magnetic Resonance Guided Radiation Therapy

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Brigham and Women's Hospital
Study ID
NCT04368702
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Viewray MRIdian® Linac — RADIATION
    MR-image guided radiation will be administered per disease site standards.

Study Details

This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.

Key Dates

Start date
May 1, 2021
Status verified
Jan 2026
Primary completion
Jun 18, 2029
Completion
Jun 18, 2029

Study Design

Enrollment
70 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Phase I - Gastric Cancer
    The research study procedures include: * Screening for eligibility * Study treatment including evaluations * MR-image guided radiation will be administered per disease site standards. * Follow up visits * Questionnaires
  • Experimental: Phase I - Breast Cancer
    The research study procedures include: * Screening for eligibility * Study treatment including evaluations * MR-image guided radiation will be administered per disease site standards. * Follow up visits * Questionnaires
  • Experimental: Phase I - Mantle Cell Lymphoma
    The research study procedures include: * Screening for eligibility * Study treatment including evaluations * MR-image guided radiation will be administered per disease site standards. * Follow up visits * Questionnaires
  • Experimental: Phase I - Larynx
    The research study procedures include: * Screening for eligibility * Study treatment including evaluations * MR-image guided radiation will be administered per disease site standards. * Follow up visits * Questionnaires
  • Experimental: Phase I - Bladder
    The research study procedures include: * Screening for eligibility * Study treatment including evaluations * MR-image guided radiation will be administered per disease site standards. * Follow up visits * Questionnaires

Primary Outcome Measure

Number of Patients and delivering MR-image guided radiation-Phase I [ Time Frame: 5 weeks ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Brigham & Women's HospitalBostonMassachusetts02115
Raymond Mak, MD
Raymond Mak, MD (PRINCIPAL_INVESTIGATOR)
Dana Farber Cancer InstituteBostonMassachusetts02115
Raymond Mak, MD
Raymond Mak, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Boston, MA

By condition
Bladder cancerGastric cancer
By specialty
OncologyUrologyGI oncology
By research site
Brigham & Women's Hospital· Boston, MADana Farber Cancer Institute· Boston, MA

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