Computational Neuroscience of Language Processing in the Human Brain

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT05222594
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • Behavioral tasks during intracranial monitoring — OTHER
    Participants will listen to sentences and stories while neural data are recorded through electrodes placed for clinical purposes.

Study Details

Language is a signature human cognitive skill, but the precise computations that support language understanding remain unknown. This study aims to combine high-quality human neural data obtained through intracranial recordings with advances in computational modeling of human cognition to shed light on the construction and understanding of speech.

Key Dates

Start date
Apr 2, 2021
Status verified
May 2026
Primary completion
Mar 31, 2027
Completion
Mar 31, 2027

Study Design

Enrollment
40 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Other: Epileptic participants undergoing intracranial monitoring
    Patients with pharmaco-resistant epilepsy undergoing intracranial monitoring involving the left cerebral hemisphere.

Primary Outcome Measure

Cortical maps of linguistic responses [ Time Frame: Throughout intracranial monitoring period, up to approximately 10 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Massachusetts General HospitalBostonMassachusetts02114
Robert M Richardson, MD, PhD
[email protected]
Erin Donahue, PhD
[email protected]
Robert M Richardson, MD, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Boston, MA

By condition
Epilepsy
By specialty
NeurologyBrain disorders
By research site
Massachusetts General Hospital· Boston, MA

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