Paid Clinical Trials in Massachusetts

Massachusetts has 3,587 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,587 clinical trials

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A Study of Brenipatide in Participants With Opioid Use Disorder

for Opioid Use Disorder

Drug: Brenipatide

38 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07420283·Phase 2·Recruiting

Apply to this trial

Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Boston

Sponsor: David Avigan

Sex: All·Age: All ages

Code: NCT07374029·Phase 1·Recruiting

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Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma

for Lymphoma

Drug: Venetoclax

1 location in Boston

Sponsor: Gottfried von Keudell, MD PhD

Sex: All·Age: 18+

Code: NCT06510309·Phase 2·Recruiting

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Distance-Based Exercise to Preserve Function and Prevent Disability

for Hematopoietic and Lymphatic System Neoplasm

17 locations incl. Dublin

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07059884·Recruiting

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A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High Altitude in Bolivia

for Hypertensive Disorder of Pregnancy

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07312227·Recruiting

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Improving Outcomes of Older Adults Undergoing Ostomy Surgery

for Ostomy - Ileostomy or Colostomy

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07424586·EARLY_Phase 1·Recruiting

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Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

for Solid Tumor

Drug: Givastomig

3 locations incl. Goodyear

Sponsor: I-Mab Biopharma US Limited

Sex: All·Age: 18+

Code: NCT07432295·Phase 2·Recruiting

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Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer

for Hereditary Cancer Syndromes

1 location in Boston

Sponsor: Nest Genomics

Sex: All·Age: 18 - 49

Code: NCT06654466·Recruiting

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A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

for Familial Pulmonary Fibrosis

Drug: Nerandomilast

13 locations incl. Los Angeles

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07201922·Phase 3·Recruiting

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A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

for Sepsis

16 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 80

Code: NCT07215702·Phase 2·Recruiting

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Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

for Carcinoma, Renal Cell

Drug: PF-08634404

101 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07227415·Phase 1, Phase 2·Recruiting

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TIL Therapy in cSCC and MCC

for Cutaneous Squamous Cell Carcinoma

1 location in Boston

Sponsor: Karam Khaddour, MD, MS

Sex: All·Age: 18+

Code: NCT07288073·Phase 2·Recruiting

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A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

for Overweight

Drug: Eloralintide

54 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07392190·Phase 3·Recruiting

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A Study of Brenipatide in Adult Participants With Schizophrenia

for Schizophrenia

Drug: Brenipatide

31 locations incl. Little Rock

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 55

Code: NCT07410507·Phase 2·Recruiting

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Identifying Substance Use Consequences

for Substance Use Disorder (SUD)

1 location in Belmont

Sponsor: Mclean Hospital

Sex: All·Age: 18+

Code: NCT07503067·Recruiting

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Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

for Osteoarthritis

Drug: Eloralintide

37 locations incl. Mobile

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07353931·Phase 3·Recruiting

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A Study of Brenipatide in Adult Participants With Major Depressive Disorder

for Depressive Disorder, Major

Drug: Brenipatide

32 locations incl. Moorpark

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07412756·Phase 3·Recruiting

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A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

29 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting

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A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

for Advanced Solid Tumor

6 locations incl. Boston

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT07213830·Phase 1, Phase 2·Recruiting

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A Digital Health Intervention to Improve Physical Function and Wellness of Lung Cancer Survivors

for Advanced Lung Cancer

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07227623·Recruiting

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A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

for Obesity

Drug: Eloralintide

41 locations incl. Tuscaloosa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07321886·Phase 3·Recruiting

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A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus

for Type II Diabetes Mellitus

31 locations incl. Birmingham

Sponsor: Corxel Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT07340320·Phase 2·Recruiting

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Piloting a Deaf Accessible Pre-Treatment for AUD

for Alcohol Use Disorder

1 location in Shrewsbury

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT07269119·Recruiting

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A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

for Dystonia

37 locations incl. Birmingham

Sponsor: Vima Therapeutics

Sex: All·Age: 18 - 65

Code: NCT07304089·Phase 2·Recruiting

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Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

for Serious Mental Illness

1 location in Worcester

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07359157·Recruiting

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SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers

for Breast Cancer

11 locations incl. Los Angeles

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06896474·Recruiting

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Genetics of Neonatal Encephalopathy and Related Disorders

for Neonatal Encephalopathy

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT07165938·Recruiting

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INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

for Type 1 Diabetes Mellitus

10 locations incl. Los Angeles

Sponsor: Mannkind Corporation

Sex: All·Age: 10 - 17

Code: NCT07224321·Phase 2·Recruiting

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Voice Therapy Per the Rehabilitation Treatment Specification System

for Muscle Tension Dysphonia

5 locations incl. Atlanta

Sponsor: Massachusetts General Hospital

Sex: All·Age: 14+

Code: NCT06152627·Recruiting

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Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness

for Persian Gulf Syndrome

10 locations incl. Berkeley

Sponsor: University of Utah

Sex: All·Age: 18+

Code: NCT06716411·Recruiting

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CF Wellness Program

for Cystic Fibrosis (CF)

3 locations incl. Denver

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07071324·Recruiting

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Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

for Prosthetic-joint Infection

9 locations incl. Sarasota

Sponsor: Peptilogics

Sex: All·Age: 18 - 80

Code: NCT07214311·Phase 2, Phase 3·Recruiting

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Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy)

for Relapsed / Refractory Osteosarcoma

2 locations incl. Los Angeles

Sponsor: Lantheus Medical Imaging

Sex: All·Age: 12+

Code: NCT07357519·Phase 1, Phase 2·Recruiting

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

77 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting

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A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax

for Acute Myeloid Leukaemia (AML)

Drug: Venetoclax

2 locations incl. Boston

Sponsor: Jacqueline Garcia, MD

Sex: All·Age: 18+

Code: NCT07148180·Phase 1, Phase 2·Recruiting

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Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

Drug: Povorcitinib

25 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12 - 17

Code: NCT07213973·Phase 2·Recruiting

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PrEP4U: Assessing the Effectiveness of Integrated Same-Day Lenacapavir Initiation and Follow-up Choice on PrEP Persistence

for HIV Pre-exposure Prophylaxis Use

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07335289·Not Yet Recruiting

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

for Attention Deficit Hyperactivity Disorder (ADHD)

1 location in Boston

Sponsor: Gagan Joshi

Sex: All·Age: 8 - 18·Accepts healthy volunteers

Code: NCT06853665·Phase 4·Recruiting

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Enjoying Affordable and Tasty Food Together

for Food Insecurity

1 location in Lowell

Sponsor: University of Massachusetts, Lowell

Sex: All·Age: 40+

Code: NCT07036757·Recruiting

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The Impact of Dry Needling on Electrophysiological and Ultrasound-based Biomarkers for Myofascial Pain

for Trigger Point in Trapezius Muscle

2 locations incl. Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18 - 80

Code: NCT07270276·Recruiting

Apply to this trial