Distance-Based Exercise to Preserve Function and Prevent Disability

Conditions

• Hematopoietic and Lymphatic System Neoplasm
• Localized Malignant Solid Neoplasm

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Exercise intervention — OTHER
  Complete supervised TH progressive resistance exercise sessions
• Telemedicine — OTHER
  Complete supervised TH progressive resistance exercise sessions
• Aerobic Exercise Intervention — OTHER
  Complete unsupervised aerobic exercise sessions
• Dumbbell Exercise Intervention — OTHER
  Receive adjustable-weight dumbbells
• Accelerometry — PROCEDURE
  Wear accelerometer
• Questionnaire Administration — OTHER
  Ancillary studies
• Interview — OTHER
  Ancillary studies
• Electronic Health Record Review — OTHER
  Ancillary studies

Study Details

This clinical trial studies whether an exercise program can be successfully delivered to patients receiving treatment for cancer through virtual sessions and allow patients to exercise in their own home. Treatments for cancer can cause side effects such as fatigue and loss of strength. These side effects can make it difficult to work, take care of family, and do other things the patient wants to do. Preliminary research shows that exercise can help prevent some of these side effects, but it can be more difficult to start an exercise program when a patient is receiving cancer treatment. The exercise program in this study is delivered through telehealth (TH) video calls. The TH sessions are delivered by trained staff that supervise resistance exercises. The trained staff also provide guidance to the patient on completing unsupervised aerobic sessions on their own. This may be a successful way to deliver an exercise program and make it easier for cancer patients to exercise in their own home during treatment.

Key Dates

Start date

Feb 11, 2026

Status verified

Apr 2026

Primary completion

Jan 1, 2027

Completion

Feb 18, 2027

Study Design

Enrollment

104 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Arms

• Experimental: Supportive care (DEFEND)
  Patients complete supervised TH exercise sessions consisting of progressive resistance exercise BIW and complete unsupervised aerobic exercise sessions over 30 minutes TIW until the end of SOC chemotherapy or up to a total of 6 months, whichever comes first, in the absence of disease progression or unacceptable toxicity. Patients also receive adjustable-weight dumbbells on study and wear an accelerometer throughout the study.

Primary Outcome Measure

Percentage of completed exercise sessions (Feasibility) [ Time Frame: Up to 6 months ]

Central Contacts

• Lilli Johnson
  773-834-4091
  [email protected]

Locations (17)

Find similar trials in Dublin, CA

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