Paid Clinical Trials in Illinois

Illinois has 2,968 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,971 clinical trials

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Training for Urinary Leakage Improvement After Pregnancy

for Urinary Incontinence

7 locations incl. San Diego

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 18+

Code: NCT06411158·Recruiting

Apply to this trial

Cognitive Training as an Adjunct to Ketamine in Real-world Clinics

for Depression

3 locations incl. Oakland

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 80

Code: NCT06526078·Enrolling By Invitation

A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

for Systemic Sclerosis (SSc)

Drug: Efgartigimod PH20 SC

9 locations incl. Phoenix

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06655155·Phase 2·Recruiting

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A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

for Developmental and Epileptic Encephalopathy

31 locations incl. Little Rock

Sponsor: Longboard Pharmaceuticals

Sex: All·Age: 2 - 65

Code: NCT06719141·Phase 3·Recruiting

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The SEQUENCE Trial: Evaluating Diagnostic Yield of Robotic-assisted Bronchoscopy When Staging EBUS is Performed First or Second in the Same Procedure

for Pulmonary Nodules

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06676956·Recruiting

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Study to Assess the Ability of the Portable Scalp Cooling System (PSCS) to Prevent Hair Loss

for Alopecia

2 locations incl. Tucson

Sponsor: Cooler Heads Care Inc.

Sex: Female·Age: 21+

Code: NCT05484973·Recruiting

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Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

for Heart Failure

6 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT06517186·Recruiting

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TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections

for Sepsis

2 locations incl. Peoria

Sponsor: Inflammatix

Sex: All·Age: 18+

Code: NCT06637904·Recruiting

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A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers

for Oral Squamous Cell Carcinoma

4 locations incl. Duarte

Sponsor: Privo Technologies

Sex: All·Age: 18 - 100

Code: NCT05893888·Phase 2, Phase 3·Recruiting

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Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma

for Asthma

Drug: Lunsekimig

54 locations incl. Saraland

Sponsor: Sanofi

Sex: All·Age: 18 - 80

Code: NCT06676319·Phase 2·Recruiting

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A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)

for Von Willebrand Disease (VWD)

11 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: Up to 17

Code: NCT05582993·Phase 3·Recruiting

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Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

for Obstetrical Complications

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT06605118·Phase 3·Recruiting

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A Multi-Country Observational Study of Safety and Effectiveness of Elfabrio® in Fabry Patients

for Fabry Disease

6 locations incl. Birmingham

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: 18+

Code: NCT06663358·Recruiting

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Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

for Breast Reconstruction

22 locations incl. Los Angeles

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06575192·Phase 3·Recruiting

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Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Aflibercept

4 locations incl. Los Angeles

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06121180·Phase 2·Recruiting

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A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

for Myasthenia Gravis

17 locations incl. San Francisco

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06298565·Recruiting

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PULSED AF Post-Approval Study

for Atrial Fibrillation

18 locations incl. Tampa

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT06578104·Recruiting

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A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

for Systemic Sclerosis

15 locations incl. Orange

Sponsor: Nkarta, Inc.

Sex: All·Age: 18 - 75

Code: NCT06733935·Phase 1, Phase 2·Recruiting

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Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

for Gastrointestinal Cancer

13 locations incl. Santa Monica

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06596694·Phase 1, Phase 2·Recruiting

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Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

for Spinal Cord Injury

7 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06529094·Recruiting

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POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse Treatment

for Pelvic Organ Prolapse

9 locations incl. Birmingham

Sponsor: Medstar Health Research Institute

Sex: Female·Age: 18+

Code: NCT06634459·Recruiting

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Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

for Tibial Plateau Fractures

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06639503·Phase 1·Recruiting

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The INFLUENTIAL Trial- Evaluation of National Inpatient Influenza Vaccination Program

for Influenza

2 locations incl. Chicago

Sponsor: University of Colorado, Denver

Sex: All·Age: 6 Months - 99·Accepts healthy volunteers

Code: NCT05832307·Recruiting

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Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

for Diabetic Nephropathies

Drug: Sotagliflozin

13 locations incl. Stanford

Sponsor: Alessandro Doria

Sex: All·Age: 18 - 75

Code: NCT06217302·Phase 3·Recruiting

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Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohn Disease

43 locations incl. Fairhope

Sponsor: Abivax S.A.

Sex: All·Age: 18 - 75

Code: NCT06456593·Phase 2·Recruiting

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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for Age-related Macular Degeneration (AMD)

Drug: Cemdisiran

153 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT06541704·Phase 3·Recruiting

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Knotless Implants As an Alternative for Capsular Closure in Primary Hip Arthroscopy: a Prospective, Multi-Center Study

for Femoro Acetabular Impingement

1 location in Des Plaines

Sponsor: American Hip Institute

Sex: All·Age: 18 - 60

Code: NCT06500364·Phase 4·Recruiting

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TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

for Breast Cancer

11 locations incl. Birmingham

Sponsor: Ana C Garrido-Castro, MD

Sex: All·Age: 18+

Code: NCT06533826·Phase 2·Recruiting

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Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

for Scleroderma, Diffuse

14 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06655896·Phase 2·Recruiting

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A Study to Assess How the Drug Moves Through the Body, Adverse Events, and Tolerability of Oral ABBV-722 Capsules of Single and Multiple Ascending Doses in Adult Participants and Single Doses in Adult Asian Participants

for Healthy Volunteer

1 location in Grayslake

Sponsor: AbbVie

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06673238·Phase 1·Recruiting

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Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients

for Malnutrition, Child

5 locations incl. Atlanta

Sponsor: Fresenius Kabi

Sex: All·Age: 1 Month - 17

Code: NCT06049680·Phase 4·Recruiting

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Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting

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AI Echocardiographic Screening of Cardiac Amyloidosis

for Cardiac Amyloidosis

4 locations incl. Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 22+

Code: NCT06664866·Enrolling By Invitation

Reducing Disparities in Urinary Control Symptoms for Minority Women

for Urinary Incontinence (UI)

2 locations incl. Chicago

Sponsor: University of Chicago

Sex: Female·Age: 18+

Code: NCT06798311·Recruiting

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A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

for Advanced Breast Cancer

35 locations incl. Springdale

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06638307·Phase 1·Recruiting

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Hyrax Vs. Invisalign Palatal Expander Clinical Study

for Malocclusions

4 locations incl. Laguna Hills

Sponsor: Align Technology, Inc.

Sex: All·Age: 6 - 11

Code: NCT06662279·Recruiting

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Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy

for Ventricular Tachycardia

5 locations incl. Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06138873·Recruiting

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Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia

for Hypertension, Pregnancy-Induced

2 locations incl. Chicago

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT06220721·Recruiting

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Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

for Classic Follicular Lymphoma

Drug: Mosunetuzumab

267 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06337318·Phase 3·Recruiting

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A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

92 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting

Apply to this trial