Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Chicago
Study ID
NCT06639503
Phase
PHASE1
Status
Recruiting

Conditions

  • Tibial Plateau Fractures

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Bupivacain — DRUG
    5mL 0.25% bupivacain

Study Details

The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the participant surgical incision. The investigators hope to discover if providing numbing medication to a nerve that controls pain in a larger area of the knee (a nerve block), might be better at post-operative pain control.

Key Dates

Start date
Nov 1, 2024
Status verified
Feb 2026
Primary completion
Sep 1, 2026
Completion
Oct 14, 2026

Study Design

Enrollment
38 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • No Intervention: Peri-incisional local anesthesia
    subjects randomized to peri-incisional local anesthesia administration will receive an injection of 25 ml of 0.25% bupivacaine across all incisions at the time of wound closure (standard of care)
  • Experimental: Genicular nerve blockade
    Subjects randomized to genicular nerve block will receive a fluoroscopic guided injection of 5 ml of 0.25% bupivacaine at the described locations of the superolateral genicular nerve, super medial genicular nerve, inferomedial genicular nerve, recurrent fibular nerve, and infrapatellar branch of the saphenous nerve under fluoroscopic guidance at the time of wound closure

Primary Outcome Measure

Pain Ratings from Visual Analog Scale (VAS) [ Time Frame: one hour, two hours, and discharge from PACU ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of ChicagoChicagoIllinois60637
Anthony Christiano, MD
Anthony Christiano, MD (PRINCIPAL_INVESTIGATOR)

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