Non-small cell lung cancer (NSCLC) Clinical Trials in Dallas, TX
As of June 2026, 48 paid clinical trials are recruiting for Non-small cell lung cancer (NSCLC) in Dallas, Texas. Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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48 clinical trials for Non-small cell lung cancer (NSCLC)
·Clear filters·↓ Download CSVA Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors
Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors
A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors
A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study of DM005 in Patients With Advanced Solid Tumors
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients
A Study of VET3-TGI in Patients With Solid Tumors
A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
A Study of KK2269 in Adult Participants With Solid Tumors
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors
A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments, Using Multiomics
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
About research studies in Dallas
Dallas has approximately 1,631 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Top Research Study Locations in Dallas
Researchers run research studies in Dallas, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Texas Southwestern Medical Center | Heart Failure, Advanced Breast Cancer, Prostate Cancer | 205 |
| UT Southwestern Medical Center | Hypertension, Renal Cell Carcinoma, Cystic Fibrosis | 173 |
| UT Southwestern/Simmons Cancer Center-Dallas | Malignant Solid Neoplasm, Stage IVB Prostate Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8 | 91 |
| University of Texas Southwestern | Neuroblastoma, Cystic Fibrosis, Lymphoma, Non-Hodgkin | 64 |
| Baylor University Medical Center | Heart Failure, Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 48 |
| Parkland Memorial Hospital | Stage IIIB Lung Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8, Endometrial Clear Cell Adenocarcinoma | 34 |
| Mary Crowley Cancer Research | Advanced Solid Tumor, Solid Tumor, Advanced Cancer | 30 |
| Medical City Dallas Hospital | Malignant Solid Neoplasm, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 27 |
| The University of Texas Southwestern Medical Center | Anxiety, Breast Cancer, Depression Disorders | 27 |
| UT Southwestern | AQP4+ NMOSD, Acute Kidney Injury, Advanced Endometrial Carcinoma | 25 |
| Retina Foundation of the Southwest | Stargardt Disease, Age-Related Macular Degeneration, Amblyopia | 24 |
| UT Southwestern Simmons Cancer Center - RedBird | Stage IVB Prostate Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 | 23 |
| Baylor Scott & White Research Institute | Emphysema, Interstitial Lung Disease, Acute Respiratory Failure | 22 |
| Children's Medical Center Dallas | Niemann-Pick Type C Disease, Acute Kidney Injury, Acute Kidney Injury Due to Sepsis | 17 |
| VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX | Cirrhosis, Acute Kidney Injury, Adult Growth Hormone Deficiency | 17 |
| Zenos Clinical Research | Diabetic Peripheral Neuropathic Pain, Gout, Type 2 Diabetes | 17 |
| Methodist Dallas Medical Center | Achalasia, Acute Kidney Injury (AKI), BK Viremia | 16 |
| GSK Investigational Site | Chickenpox, HIV Infections, Neoplasms | 15 |
| Texas Oncology | Advanced Melanoma, Advanced Non-Small-Cell Lung Cancer, Advanced/Metastatic Solid Tumors | 13 |
| Texas Oncology - DFW | Breast Cancer, Endometrial Cancer, Advanced Lung Cancer | 11 |
| Children's Medical Center | Neuroblastoma, Ewing Sarcoma, Osteosarcoma | 10 |
| Methodist Dallas Medical Center- Clinical Research Institute | Trauma, Gastro-Intestinal Disorder, Chronic Pancreatitis | 10 |
| Clinical Trial Site | Advanced Breast Cancer, Advanced Hepatocellular Carcinoma, Breast Cancer | 9 |
| University of Texas Southwestern Medical Center at Dallas | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 9 |
| Baylor Scott & White Health | Acute Myeloid Leukemia, Cancer, Distal Esophageal Spasm | 8 |
Active & Upcoming Studies in Dallas (2026)
Recruiting trials in Dallas grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (472 active studies)
- Molecular Breast Imaging (MBI)-Guided Biopsy · Smart Breast Corp.
- Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization · University of Colorado, Denver
Cardiovascular (130 active studies)
- Improving Veteran Referral to Cardiac Rehabilitation · VA Office of Research and Development
- Value of Potassium Magnesium Citrate in Preventing and Treating Hypertension in African Americans · Phase 2 · University of Texas Southwestern Medical Center
Neurology & pain (80 active studies)
- Cholinergic Enhancement of Theta · EARLY_Phase 1 · University of Texas Southwestern Medical Center
- Pediatric Epilepsy · University of Texas Southwestern Medical Center
Diabetes & metabolic (73 active studies)
- RAndomized EHR-based Prescribing to Improve Disease-modifying Therapies for Cardio-Kidney-Metabolic Care (RAPID-CKM) · Baylor Research Institute
- A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight · Phase 2 · Eli Lilly and Company
Mental health & behavior (38 active studies)
- Neuronavigated aiTBS for TRD · University of Texas Southwestern Medical Center
- Parent-Adolescent Relationships, Emotional Regulation, and HRV in Adolescents With Depression · University of Texas Southwestern Medical Center
Eye & vision (32 active studies)
- A Study of Outcomes Following Bio-Reinforced Canaloplasty in Eyes With Open-Angle Glaucoma · Iantrek, Inc.
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
Pediatric (23 active studies)
- Parent-Adolescent Relationships, Emotional Regulation, and HRV in Adolescents With Depression · University of Texas Southwestern Medical Center
- Video vs. Direct Laryngoscopy for Less Invasive Surfactant Administration · University of Texas Southwestern Medical Center
HIV / STI (16 active studies)
- Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM · Yale University
- HIV/HBV/HCV Triple Screening in Primary Care · University of Texas Southwestern Medical Center
Vaccines (10 active studies)
- A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults · Phase 3 · ModernaTX, Inc.
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Common conditions studied in Dallas
- Heart Failure (37 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Breast Cancer (35 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Advanced Solid Tumor (24 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Obesity (24 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Prostate Cancer (20 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Endometrial Cancer (17 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Dallas
- University of Texas Southwestern Medical Center
- Eli Lilly and Company
- AstraZeneca
- National Cancer Institute (NCI)
- Baylor Research Institute
Local regulations and guidelines
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Dallas. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Dallas
Hipa.ai aggregates every recruiting study in Dallas from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Dallas?
There are approximately 1,631 recruiting clinical trials in Dallas, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Dallas pay participants?
Most recruiting trials in Dallas compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Dallas?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Dallas?
The most common conditions under active study in Dallas include Heart Failure (37), Breast Cancer (35), Advanced Solid Tumor (24), Obesity (24), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Dallas?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Dallas on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Dallas?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Dallas?
Recruiting research sites in Dallas include University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Dallas right now?
The largest active categories in Dallas are Cancer & tumors (472), Cardiovascular (130), Neurology & pain (80). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.