Paid Clinical Trials in Cleveland, OH

As of June 2026, 1,346 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,346 clinical trials

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Virtual Patient Groups for Sarcoidosis Associated Fatigue

for Sarcoidosis

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07073963·Recruiting

Apply to this trial

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for Parkinson Disease

25 locations incl. Little Rock

Sponsor: Appello Pharmaceuticals, Inc.

Sex: All·Age: 30 - 80

Code: NCT07432958·Phase 2·Recruiting

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Metabolic Impacts of Ren-Nu: A Dietary Program for Polycystic Kidney Disease

for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

1 location in Cleveland

Sponsor: Richard Fatica

Sex: All·Age: 18+

Code: NCT07454174·Recruiting

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A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

for Catecholaminergic Polymorphic Ventricular Tachycardia

4 locations incl. Boston

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 7+

Code: NCT07148089·Phase 1·Recruiting

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Youth Empowerment and Safety Intervention

for Suicide

1 location in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 12 - 17

Code: NCT07214233·Recruiting

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A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

for Relapsed Refractory Multiple Myeloma

48 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07391657·Phase 3·Recruiting

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A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-Resistant Prostate Cancer

20 locations incl. Goodyear

Sponsor: Kyntra Bio

Sex: Male·Age: 18+

Code: NCT06842498·Phase 2·Recruiting

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Application of a Prediction Model for Directing Antibiotic Use in the Treatment of Urinary Tract Infection in an Ambulatory Setting

for Urinary Tract Infections

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Female·Age: 18+

Code: NCT06976125·Recruiting

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Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Recovery After Colorectal Surgery

for Pain After Surgery

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+

Code: NCT07026786·Recruiting

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Ambulatory Long Length URodynamics Evaluation

for Urology

7 locations incl. Hanover

Sponsor: Bright Uro

Sex: All·Age: 22+

Code: NCT07425015·Recruiting

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A Study of ELA026 in Participants With Relapsed/Refractory (R/R) T/NK Cell Malignancies (TCMs)

for T Cell Malignancies

4 locations incl. New Haven

Sponsor: Electra Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07465835·Phase 1·Recruiting

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Validation and Usability Study of the SleepView+ Home Sleep Testing System for the Evaluation of Moderate to Severe Obstructive Sleep Apnea.

for Obstructive Sleep Apnea

4 locations incl. Redwood City

Sponsor: Beacon Biosignals

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT07476313·Enrolling By Invitation

Musculoskeletal Cancers Remote Monitoring and Care

for Osteosarcoma

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07129226·Recruiting

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KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for Bladder Cancer

3 locations incl. San Francisco

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07232602·Phase 1, Phase 2·Recruiting

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A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

29 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting

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Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics

for Periodontitis, Diabetes Mellitus Type 2

1 location in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 18+

Code: NCT07298057·EARLY_Phase 1·Recruiting

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Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

for Metastatic Ewing Sarcoma

17 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 1+

Code: NCT07194044·Phase 1·Recruiting

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A Superiority Trial of Radiofrequency Ablation for Low Back Pain

for Chronic Low Back Pain (CLBP)

3 locations incl. Atlanta

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07222462·Recruiting

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Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for Ventral Hernia

11 locations incl. Riverside

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07226791·Phase 2·Recruiting

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A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer

for Relapsed/Refractory Small Cell Lung Cancer

Drug: Nivolumab

5 locations incl. Detroit

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07325136·Phase 1, Phase 2·Recruiting

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

77 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting

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GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

for Type 1 Diabetes Mellitus

34 locations incl. Little Rock

Sponsor: Medtronic MiniMed, Inc.

Sex: All·Age: 7 - 85

Code: NCT07228117·Recruiting

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Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease

for Parkinson's Disease

1 location in Cleveland

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT06857851·Not Yet Recruiting

Decitabine and Nivolumab in Participants With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

for Head and Neck Cancer

Drug: Nivolumab

1 location in Cleveland

Sponsor: Kyunghee Burkitt, DO, PhD

Sex: All·Age: 18+

Code: NCT07216833·Phase 1·Not Yet Recruiting

Replication and Evaluation of the RISE-APS Model In New Contexts

for Elder Abuse

4 locations incl. Reseda

Sponsor: RISE Collaborative

Sex: All·Age: 60+

Code: NCT07368257·Not Yet Recruiting

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease

for Metastatic Breast Cancer in the Liver

4 locations incl. Tampa

Sponsor: Delcath Systems Inc.

Sex: All·Age: 18+

Code: NCT06875128·Phase 2·Recruiting

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A Study to Investigate the Improvement of Photosensitivity in Terms of Skin Lesions Associated With CEP Following Administration of Oral ATL-001 (Ciclopirox Oral Solution) in Participants Aged >18 Years of Age With CEP

for Congenital Erythropoietic Porphyria (CEP)

1 location in Cleveland

Sponsor: Atlas Molecular Pharma

Sex: All·Age: 18+

Code: NCT07024316·Phase 1, Phase 2·Recruiting

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A Trial of TAK-861 for the Treatment of Narcolepsy With Cataplexy

for Narcolepsy Type 1 (NT1)

11 locations incl. Redwood City

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT07363720·Phase 3·Recruiting

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Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

for Hepatitis

Drug: Larsucosterol

48 locations incl. Birmingham

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 18+

Code: NCT07428538·Phase 3·Recruiting

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Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD) Trial

for Alcohol-associated Hepatitis

6 locations incl. Indianapolis

Sponsor: Samer Gawrieh

Sex: All·Age: 18 - 70

Code: NCT07060638·Phase 2·Recruiting

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

211 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting

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Neoadjuvant Darovasertib in Primary Uveal Melanoma

for Uveal Melanoma

35 locations incl. Scottsdale

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07015190·Phase 3·Recruiting

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Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma Refractory

12 locations incl. San Francisco

Sponsor: CellCentric Ltd.

Sex: All·Age: 18+

Code: NCT07096778·Phase 2·Recruiting

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Home-based Vision Therapy

for Convergence Insufficiency

1 location in Cleveland

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06886737·Phase 1·Recruiting

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A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4)

for Chronic Hepatitis D Infection

8 locations incl. Davis

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18 - 99

Code: NCT07298330·Phase 3·Recruiting

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A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

for Prostatic Neoplasms

Drug: Pasritamig

3 locations incl. Sarasota

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07319871·Phase 1·Recruiting

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Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia

for Spinal Cord Injury Cervical

1 location in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 22 - 65

Code: NCT07225582·Recruiting

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Antiseptic-Coated Sutures and Pancreatic Fistula Risk After Pancreatoduodenectomy

for Pancreatoduodenectomy

3 locations incl. Akron

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07318493·Recruiting

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A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

for Chronic Idiopathic Constipation (CIC)

Drug: Tenapanor

109 locations incl. Foley

Sponsor: Ardelyx

Sex: All·Age: 18 - 80

Code: NCT07382167·Phase 3·Recruiting

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Laser Ablation a Salvage Treatment for Obstructive Benign Prostatic Hyperplasia

for Benign Prostatic Hyperplasia (BPH)

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: Male·Age: 40+

Code: NCT07016620·Recruiting

Apply to this trial