Paid Clinical Trials in Cleveland, OH

As of June 2026, 1,346 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,346 clinical trials

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A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

for Advanced Biliary Tract Cancer

23 locations incl. Duarte

Sponsor: J-Pharma Co., Ltd.

Sex: All·Age: 18+

Code: NCT07265674·Phase 3·Recruiting

Apply to this trial

Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor

for Malignant Peripheral Nerve Sheath Tumors

1 location in Cleveland

Sponsor: Ankit Mangla, MD

Sex: All·Age: 12+

Code: NCT07549022·Phase 1, Phase 2·Not Yet Recruiting

A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.

for Exocrine Pancreatic Insufficiency (EPI)

9 locations incl. Scottsdale

Sponsor: Aimmune Nestlé Health Science US R&D, LLC

Sex: All·Age: 18 - 85

Code: NCT07559175·Phase 2·Not Yet Recruiting

Phase 2 Study to Assess the Safety and Efficacy of ANG003

for Exocrine Pancreatic Insufficiency (EPI)

26 locations incl. Long Beach

Sponsor: Anagram Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07450547·Phase 2·Recruiting

Apply to this trial

PREcision MEDicine In Achalasia (PREMEDIA)

for Type I Achalasia

13 locations incl. Scottsdale

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293650·Phase 3·Recruiting

Apply to this trial

Baby Steps to Care

for Prenatal Follow Up Care

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07499648·Recruiting

Apply to this trial

Visugromab in Cachexia International Trial

for Cancer-associated Cachexia

6 locations incl. Clermont

Sponsor: CatalYm GmbH

Sex: All·Age: 18+

Code: NCT07112196·Phase 2, Phase 3·Recruiting

Apply to this trial

Neural Correlates of Suicidal Behavior in Youth

for Suicidal Ideation

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 14 - 24·Accepts healthy volunteers

Code: NCT07568054·Not Yet Recruiting

Menopausal HT for Women Living With HIV (HoT)

for HIV Infection

23 locations incl. Birmingham

Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Sex: Female·Age: 40 - 60

Code: NCT06856174·Phase 4·Recruiting

Apply to this trial

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for Solid Tumors

Drug: INCB161734

68 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07522073·Phase 3·Recruiting

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Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

for Atrial Fibrillation (AF)

22 locations incl. Birmingham

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT07298473·Recruiting

Apply to this trial

Bowel Continence Across the Lifespan in People With Spina Bifida

for Spina Bifida

24 locations incl. Birmingham

Sponsor: David Chu

Sex: All·Age: 5+

Code: NCT07390318·Recruiting

Apply to this trial

PEP Buddy in Pulmonary Rehabilitation

for COPD

2 locations incl. Cincinnati

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 89

Code: NCT07404826·Not Yet Recruiting

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndrome

18 locations incl. Orange

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07422480·Phase 3·Recruiting

Apply to this trial

Intrauterine Stent Placement Following Hysteroscopic Septum Resection

for Intrauterine Adhesion

3 locations incl. Little Rock

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT07032506·Not Yet Recruiting

HPV ctDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Advanced-Stage Anal Cancer

for Anal Cancer

Drug: Retifanlimab

2 locations incl. Cleveland

Sponsor: Jennifer Dorth

Sex: All·Age: 18+

Code: NCT07425054·Phase 2·Not Yet Recruiting

HCMR Re-Imaging Study

for Hypertrophic Cardiomyopathy (HCM)

6 locations incl. Evanston

Sponsor: Christopher Kramer

Sex: All·Age: 18 - 65

Code: NCT07054073·Recruiting

Apply to this trial

Direct Comparison of Cardiac CT With TEE to Evaluate Watchman FLX LAA Occluder Device Characteristics

for Device Related Thrombosis

5 locations incl. Los Angeles

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+

Code: NCT06523166·Recruiting

Apply to this trial

Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy

for Chemotherapy-induced Peripheral Neuropathy

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07219472·Recruiting

Apply to this trial

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

for Advanced Renal Cell Carcinoma (RCC)

Drug: Cabozantinib

13 locations incl. New Haven

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07293351·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

for Alzheimer Disease

Drug: KarXT

6 locations incl. Gilbert

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT06947941·Phase 3·Recruiting

Apply to this trial

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

9 locations incl. Englewood

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting

Apply to this trial

PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

for Proteinuric Kidney Diseases

25 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT07355296·Phase 2·Recruiting

Apply to this trial

Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer

for Breast Cancer

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: Female·Age: 18 - 65

Code: NCT04362826·Recruiting

Apply to this trial

Bridging the Gap: Educating Patients on Social Determinants of Health to Improve Epilepsy Surgery Access and Outcomes

for Epilepsy

1 location in Cleveland

Sponsor: Anny Reyes

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07509190·Recruiting

Apply to this trial

Centered Surgery - Preoperative Counseling and Patient Satisfaction

for Pelvic Organ Prolapse

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07471464·Recruiting

Apply to this trial

A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas

for Glioblastoma

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07003542·Phase 2·Recruiting

Apply to this trial

Pulmonary Rehabilitation in Advanced Lung Cancer Survivors

for Non-small Cell Lung Cancer Stage III

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07104630·Phase 2·Recruiting

Apply to this trial

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

38 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361497·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Drug: Nivolumab

34 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221149·Phase 2, Phase 3·Recruiting

Apply to this trial

Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion

for Liver Transplant Disorder

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07315204·Recruiting

Apply to this trial

POP SINGER Pilot Study

for Chronic Pain

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+

Code: NCT07450131·Recruiting

Apply to this trial

Sternal Plating High Risk

for Heart Diseases

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06660186·Recruiting

Apply to this trial

Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG

for Malignant Brain Tumors

2 locations incl. Cleveland

Sponsor: Tiffany Hodges

Sex: All·Age: 18+

Code: NCT07438860·Phase 1·Not Yet Recruiting

The Improving Sleep in African American Couples Study (ISAAC)

for Obstructive Sleep Apnea (OSA)

2 locations incl. Cleveland

Sponsor: MetroHealth Medical Center

Sex: All·Age: 30+

Code: NCT07447284·Not Yet Recruiting

Evaluating Laser Otoscope for Middle Ear Effusion Detection

for Middle Ear Effusion

1 location in Cleveland

Sponsor: MSTATT LLC

Sex: All·Age: 6 Months - 18

Code: NCT07454512·Not Yet Recruiting

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

for Mitochondrial Diseases

3 locations incl. Boston

Sponsor: Khondrion BV

Sex: All·Age: 18+

Code: NCT06451757·Phase 3·Recruiting

Apply to this trial

Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation

for Heart Failure (HF)

2 locations incl. Cleveland

Sponsor: Oslo University Hospital

Sex: All·Age: 18+

Code: NCT07436299·Not Yet Recruiting

Trial of Oligometastasis SBRT With Immediate, Simulation-Free Treatment Delivery (OLIGO-SWIFT)

for Oligometastasis

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07079098·Phase 1·Recruiting

Apply to this trial

An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for Stomatitis

20 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07357597·Phase 4·Not Yet Recruiting