Paid Clinical Trials in Cleveland, OH

As of June 2026, 1,346 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,346 clinical trials

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Golcadomide With Pemetrexed, Rituximab, and Dexamethasone for Relapsed and Refractory CNS Lymphomas

for Large B-cell Lymphoma

Drug: Golcadomide

1 location in Cleveland

Sponsor: Allison Winter

Sex: All·Age: 18+

Code: NCT07608731·Phase 1·Not Yet Recruiting

A Study to Measure Mirikizumab Levels in Breast Milk of Lactating Participants Receiving Mirikizumab Therapeutically for an Approved Indication

for Lactation

5 locations incl. Glenview

Sponsor: Eli Lilly and Company

Sex: Female·Age: 3 Weeks+

Code: NCT07612267·Phase 4·Not Yet Recruiting

Living Well With Brain Cancer: A Group-Based Intervention to Promote Whole-Person Well-Being

for Brain Cancer

2 locations incl. Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT07628647·Not Yet Recruiting

Testing of GripTract-GI Endoscopic Tissue Manipulator for Use During Complex Endoscopic Polypectomies in the Colon

for Polyps Colorectal

1 location in Cleveland

Sponsor: Actuated Medical, Inc.

Sex: All·Age: 21+

Code: NCT06015607·Recruiting

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D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer

for Biliary Tract Cancer (BTC)

1 location in Cleveland

Sponsor: InnoPharmax Inc.

Sex: All·Age: 18+

Code: NCT06622057·Phase 3·Recruiting

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REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health)

for Schizophrenia

1 location in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 18 - 50

Code: NCT07006935·Not Yet Recruiting

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: Up to 18

Code: NCT07192952·Phase 3·Recruiting

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PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

for Type III Achalasia

13 locations incl. Scottsdale

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293689·Recruiting

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nVNS, CBD, and SoC for Persistent Post-Traumatic Headache

for Persistent Post Traumatic Headache

8 locations incl. Scottsdale

Sponsor: American Society of Pain and Neuroscience, Inc.

Sex: All·Age: 18 - 75

Code: NCT07624279·Phase 2·Not Yet Recruiting

Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area

for Anastomotic Leaks

8 locations incl. Orlando

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07035431·Recruiting

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Maintenance Zanzalintinib and Durvalumab in Participants With Advanced Hepatocellular Cancer

for Hepatocellular Carcinoma

Drug: Durvalumab

1 location in Cleveland

Sponsor: Amit Mahipal

Sex: All·Age: 19+

Code: NCT07226063·Phase 2·Not Yet Recruiting

Signatera Assessment in Early-Stage Endometrial Cancer

for Endometrial Cancer

9 locations incl. Birmingham

Sponsor: Natera, Inc.

Sex: Female·Age: 18+

Code: NCT07339384·Not Yet Recruiting

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting

for GIST - Gastrointestinal Stromal Tumor

8 locations incl. Los Angeles

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT07406633·Phase 2·Recruiting

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ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

for Coronary Artery Disease

16 locations incl. Phoenix

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT07559903·Not Yet Recruiting

The Canopy Cancer Collective Clinical Registry Protocol

for Gastrointestinal Neoplasms

10 locations incl. San Diego

Sponsor: Canopy Cancer Collective, LLC

Sex: All·Age: 18+

Code: NCT07605702·Not Yet Recruiting

Treatment of Antibody-Mediated Rejection (ABMR) With CarBel

for Kidney Transplant Rejection

10 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 75

Code: NCT06918990·Phase 1·Recruiting

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A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

for Systemic Sclerosis

Drug: BMS-986353

16 locations incl. Scottsdale

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 16+

Code: NCT07335562·Phase 3·Recruiting

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Health-Related Quality of Life and Metabolic Outcomes in PCOS

for PCOS (Polycystic Ovary Syndrome)

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: Female·Age: 18 - 49·Accepts healthy volunteers

Code: NCT07571915·Recruiting

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Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

for Large Cell Neuroendocrine Carcinoma

5 locations incl. Atlanta

Sponsor: Molecular Partners AG

Sex: All·Age: 18+

Code: NCT07278479·Phase 1, Phase 2·Recruiting

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Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

for Major Depressive Disorder

25 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06705478·Phase 2·Recruiting

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Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

8 locations incl. Orange

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 60+

Code: NCT06773936·Phase 2·Enrolling By Invitation

PrP-targeting siRNA Safety & Mechanism Study

for Prion Disease

5 locations incl. Boston

Sponsor: Broad Institute of MIT and Harvard

Sex: All·Age: 18+

Code: NCT07444580·Phase 1·Recruiting

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AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

for Hernia

12 locations incl. Loma Linda

Sponsor: Tissium

Sex: All·Age: 22+

Code: NCT07277946·Recruiting

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A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

for Diabetic Macular Edema

30 locations incl. Phoenix

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07553429·Phase 1, Phase 2·Recruiting

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Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)

for Familial Adenomatous Polyposis

2 locations incl. Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT06641310·Recruiting

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Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain

for Pancreatic Cancer

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07117032·Phase 1·Recruiting

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A Study of TAK-505 in Adults With Solid Tumors

for Malignant Solid Tumors

15 locations incl. Orange

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07436728·Phase 1, Phase 2·Recruiting

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Study of INCA036978 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Drug: INCA036978

22 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07441694·Phase 1·Recruiting

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An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for Cardiovascular Disease and Lipoprotein(a)

Drug: Pelacarsen

115 locations incl. Andalusia

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07517263·Phase 3·Recruiting

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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for Obesity

Drug: NNC0487-0111

202 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07567001·Phase 3·Not Yet Recruiting

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for Major Depressive Disorder

27 locations incl. Gilbert

Sponsor: Definium Therapeutics US, Inc.

Sex: All·Age: 18 - 74

Code: NCT07592689·Phase 3·Recruiting

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Dasatinib for HIV-1 Reservoir Reduction

for HIV Infections

3 locations incl. Chicago

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT07342491·Phase 1·Recruiting

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Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

14 locations incl. Birmingham

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting

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A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

10 locations incl. Birmingham

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting

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AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

24 locations incl. Dothan

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting

Apply to this trial

Humidity Asthma Interventions for Low Socioeconomic Status Children

for Pediatric Asthma

2 locations incl. Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: Up to 18

Code: NCT07453667·Recruiting

Apply to this trial

Ovarian Tissue Allo-transplantation

for Ovarian Failure

1 location in Cleveland

Sponsor: Rebecca Flyckt

Sex: Female·Age: 21 - 40·Accepts healthy volunteers

Code: NCT06673004·Not Yet Recruiting

Deutetrabenazine Treatment for Tardive Dyskinesia in Intellectual/Developmental Disabilities

for Tardive Dyskinesia

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06997198·Phase 4·Not Yet Recruiting

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

for Nonmelanoma Skin Cancer

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07241585·Not Yet Recruiting

Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System

for Tricuspid Valve Disease

35 locations incl. Birmingham

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18 - 85

Code: NCT06458907·Not Yet Recruiting