Paid Clinical Trials in Cleveland, OH

As of June 2026, 1,346 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,346 clinical trials

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A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

for Large B-cell Lymphoma

38 locations incl. Gilbert

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT07188558·Phase 3·Recruiting

Apply to this trial

Lead Evaluation for Defibrillation and Reliability Post Approval Study

for Tachyarrhythmia

46 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT07005232·Enrolling By Invitation

Implementation of Intensive Hypertension Management Approaches: Cleveland Clinic

for Hypertension (HTN)

1 location in Cleveland

Sponsor: Anita Misra-Hebert

Sex: All·Age: 18 - 85

Code: NCT07232017·Recruiting

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A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation

for Microvascular Inflammation

18 locations incl. Loma Linda

Sponsor: Biogen

Sex: All·Age: 18 - 74

Code: NCT07219043·Phase 2·Recruiting

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A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for Metastatic Non-small Cell Lung Cancer With MTAP Deletion

Drug: Navlimetostat

42 locations incl. Anchorage

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07063745·Phase 2, Phase 3·Recruiting

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Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms

for PARKINSON DISEASE (Disorder)

1 location in Cleveland

Sponsor: U: The Mind Company

Sex: All·Age: 18 - 80

Code: NCT07182058·Phase 1, Phase 2·Recruiting

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Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas

for Glioblastoma

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 19+

Code: NCT06455189·Phase 1·Not Yet Recruiting

Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

for Non Hodgkin Lymphoma

Drug: Tafasitamab

2 locations incl. Cleveland

Sponsor: Paolo Caimi, MD

Sex: All·Age: 18+

Code: NCT07225439·Phase 1·Not Yet Recruiting

Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

15 locations incl. Little Rock

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

117 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting

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Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma

for Low Grade Upper Tract Urothelial Carcinoma

7 locations incl. Lisle

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT07265947·Phase 2·Recruiting

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Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

for Endometrial Cancer

12 locations incl. Little Rock

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07444814·Phase 1·Recruiting

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Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

for Liver Cirrhoses

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18 - 70

Code: NCT07058155·Phase 4·Recruiting

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A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors

for Solid Tumors, Adult

9 locations incl. Denver

Sponsor: Hutchmed

Sex: All·Age: 18+

Code: NCT07228247·Phase 1, Phase 2·Recruiting

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A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

for Focal Epilepsy

7 locations incl. Boise

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT07219407·Phase 2·Recruiting

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A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

17 locations incl. Birmingham

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting

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A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)

for Squamous Non-small Cell Lung Cancer

Drug: Intismeran autogene

7 locations incl. Tampa

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07221474·Phase 2·Recruiting

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A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease

for Respiratory Syncytial Virus Infections

33 locations incl. Los Angeles

Sponsor: Shionogi

Sex: All·Age: 18+

Code: NCT07214571·Phase 2·Recruiting

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Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma (PDAC)

14 locations incl. Cerritos

Sponsor: SOFIE

Sex: All·Age: 18+

Code: NCT07217717·Phase 3·Recruiting

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Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for Intestinal Neoplasms

Drug: PF-08634404

150 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07222800·Phase 3·Recruiting

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Efficacy and Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome

for Short Bowel Syndrome (SBS)

4 locations incl. Rochester

Sponsor: Zealand Pharma

Sex: All·Age: 18+

Code: NCT07228403·Phase 3·Enrolling By Invitation

Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support

for Choline Deficiency

7 locations incl. Aurora

Sponsor: Protara Therapeutics

Sex: All·Age: 12+

Code: NCT06910943·Phase 2, Phase 3·Recruiting

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Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction

for Oral Cancer

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07110142·Recruiting

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A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for Clostridioides Difficile Associated Disease

135 locations incl. Athens

Sponsor: Pfizer

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07282665·Phase 3·Recruiting

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A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

for Chronic Kidney Disease

Drug: Empagliflozin

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07107945·Phase 3·Recruiting

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Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

29 locations incl. Anchorage

Sponsor: Incyte Corporation

Sex: Female·Age: 18+

Code: NCT07214779·Phase 3·Recruiting

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An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

for Multiple Sclerosis

9 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 60

Code: NCT07224373·Phase 1·Recruiting

Apply to this trial

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

22 locations incl. Birmingham

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting

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Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

20 locations incl. Phoenix

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07290569·Phase 2·Recruiting

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Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

for Biliary Tract Cancer

2 locations incl. Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 19+

Code: NCT07146646·Phase 2·Recruiting

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First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for Esophageal Squamous Cell Carcinoma

10 locations incl. Scottsdale

Sponsor: Plexium, Inc.

Sex: All·Age: 18+

Code: NCT07284186·Phase 1·Recruiting

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A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

for Small-cell Lung Cancer

28 locations incl. Aurora

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07218146·Phase 3·Recruiting

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Brain Autoregulation Research Study

for Hypotension During Surgery

1 location in Cleveland

Sponsor: Bradley Marino

Sex: All·Age: 30 Days - 30 Days

Code: NCT07221721·Not Yet Recruiting

A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

for Acromegaly

9 locations incl. Los Angeles

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06930625·Phase 3·Recruiting

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Pre-Op MRI on Margin Status for Transoral Robotic Surgery for HPV+ Tonsillar Squamous Cell Carcinoma

for Human Papilloma Virus Related Carcinoma

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07060261·Recruiting

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A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

for Small Cell Lung Cancer

Drug: Atezolizumab

9 locations incl. New Haven

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07155174·Phase 2·Recruiting

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A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

for Advanced or Metastatic Non-small Cell Lung Cancer

10 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06996782·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for Parkinson's Disease

Drug: Prasinezumab

42 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 85

Code: NCT07174310·Phase 3·Recruiting

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Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease

for Parkinson Disease

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07110376·Recruiting

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A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for Epithelial Ovarian Cancer

64 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06890338·Phase 2·Recruiting

Apply to this trial