Clinical Trials at University of Chicago

As of June 2026, 199 paid clinical trials are recruiting at University of Chicago, located at 5841 S MARYLAND AVE # 2115, CHICAGO, IL 60637-1447, phone (773) 702-4601 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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199 clinical trials at University of Chicago

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A Study of SNDX-5613 in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias

for Acute Myeloid Leukemias

26 locations incl. Burbank

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06226571·Phase 1·Recruiting

Apply to this trial

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

for Neuroendocrine Tumors

4 locations incl. Atlanta

Sponsor: Chimeric Therapeutics

Sex: All·Age: 18 - 85

Code: NCT06055439·Phase 1, Phase 2·Recruiting

Apply to this trial

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for Acute Ischemic Stroke

51 locations incl. Mobile

Sponsor: Mercy Health Ohio

Sex: All·Age: 18 - 79

Code: NCT05611242·Phase 3·Recruiting

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The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for Intracranial Aneurysm

22 locations incl. Englewood

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 18 - 75

Code: NCT02998229·Recruiting

Apply to this trial

AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion

for Aortic Aneurysm, Abdominal

39 locations incl. Birmingham

Sponsor: Shape Memory Medical, Inc.

Sex: All·Age: 18+

Code: NCT06029660·Recruiting

Apply to this trial

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

for Solid Tumor, Adult

15 locations incl. Birmingham

Sponsor: Corbus Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06265727·Phase 1, Phase 2·Recruiting

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A Phase 1/1b Study of IAM1363 in HER2 Cancers

for HER2 Mutation-Related Tumors

29 locations incl. La Jolla

Sponsor: Iambic Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06253871·Phase 1·Recruiting

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An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

for Oligometastatic Prostate Cancer (OMPC)

41 locations incl. Fayetteville

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05939414·Phase 3·Recruiting

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Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)

for Type 1 Diabetes Mellitus

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 65

Code: NCT06305286·Phase 1, Phase 2·Recruiting

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Feasibility of a Dog Training Therapy Program in UC Outpatient Youth Receiving Psychiatric Services

for Emotion Regulation

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 8 - 17

Code: NCT05788783·Recruiting

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Durometer for Measuring Uterine Tone

for Uterine Tone Disorders

1 location in Chicago

Sponsor: University of Chicago

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06284421·Recruiting

Apply to this trial

Oxygenation in Vascular Lesions of the Colon

for Vascular Lesion

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT06230731·Recruiting

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A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas

for Anal Fistula

9 locations incl. Los Angeles

Sponsor: RedDress Ltd.

Sex: All·Age: 18+

Code: NCT05641844·Recruiting

Apply to this trial

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

for Hypertension

70 locations incl. Scottsdale

Sponsor: Orchestra BioMed, Inc

Sex: All·Age: 18+

Code: NCT06059638·Recruiting

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CLN-617 Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

5 locations incl. Los Angeles

Sponsor: Cullinan Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06035744·Phase 1·Recruiting

Apply to this trial

Percutaneous Nerve Evaluation Trial Time

for Urge Incontinence

1 location in Chicago

Sponsor: University of Chicago

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06226220·Recruiting

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Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for Lung Cancer Diagnosis

36 locations incl. Los Angeles

Sponsor: Freenome Holdings Inc.

Sex: All·Age: 50+

Code: NCT06122077·Recruiting

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A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

for Hematologic Malignancy

17 locations incl. Duarte

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18+

Code: NCT06208878·Enrolling By Invitation

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

25 locations incl. Phoenix

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting

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Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

37 locations incl. Phoenix

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting

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Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

for LVAD

7 locations incl. San Francisco

Sponsor: International Consortium of Circulatory Assist Clinicians

Sex: All·Age: 18 - 100

Code: NCT06039176·Recruiting

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A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

for Advanced Solid Tumor

Drug: NXP900

10 locations incl. Phoenix

Sponsor: Nuvectis Pharma, Inc.

Sex: All·Age: 18+

Code: NCT05873686·Phase 1·Recruiting

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Nectero EAST System Clinical Study

for Abdominal Aortic Aneurysm

37 locations incl. Scottsdale

Sponsor: Nectero Medical, Inc.

Sex: All·Age: 21 - 85

Code: NCT06001918·Phase 2, Phase 3·Recruiting

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Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients

for Kidney Transplant Rejection

26 locations incl. Los Angeles

Sponsor: Eledon Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06126380·Phase 2·Enrolling By Invitation

AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

for Community-acquired Pneumonia

6 locations incl. Chicago

Sponsor: University of Manitoba

Sex: All·Age: 18+

Code: NCT05848713·Phase 3·Recruiting

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Intrathecal Morphine for Analgesia in Video-assisted and Robotic-assisted Thoracic Surgery

for Pain, Postoperative

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 80

Code: NCT05351229·Phase 4·Recruiting

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Left vs Left Randomized Clinical Trial

for Heart Failure

57 locations incl. Gilbert

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting

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A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular Carcinoma

for Advanced Hepatocellular Carcinoma

7 locations incl. Duarte

Sponsor: Iterion Therapeutics

Sex: All·Age: 18+

Code: NCT05797805·Phase 1, Phase 2·Recruiting

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SMART Exercise for PAD

for Peripheral Arterial Disease

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT06032065·Phase 3·Recruiting

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Lung Cancer Screening in High-risk Black Individuals

for Lung Cancer

2 locations incl. Chicago

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT05898594·Recruiting

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Frameless Stereotactic Radiosurgery for Intact Brain Metastases

for Brain Metastases

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT02747303·Phase 2·Recruiting

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A Trial of Post-Discharge Transitional Care for Patients With Chronic Liver Disease

for Liver Diseases

4 locations incl. Chicago

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05733832·Recruiting

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US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

37 locations incl. Phoenix

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting

Apply to this trial

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

for Heart Failure

47 locations incl. Phoenix

Sponsor: Procyrion

Sex: All·Age: 21+

Code: NCT05677100·Recruiting

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection

for COVID-19

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06008860·Phase 4·Recruiting

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

19 locations incl. Birmingham

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting

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Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for Glioma

40 locations incl. Birmingham

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT05303519·Phase 3·Recruiting

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

42 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting

Apply to this trial