Intrathecal Morphine for Analgesia in Video-assisted and Robotic-assisted Thoracic Surgery

Part of paid clinical trials in Chicago, Illinois.

Sponsor
Northwestern University
Study ID
NCT05351229
Phase
PHASE4
Status
Recruiting
Apply to this trial

Conditions

  • Pain, Postoperative

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Morphine Sulfate — DRUG
    5 mcg/kg intrathecal preservative free morphine sulfate
  • Placebo — OTHER
    Sterile saline, placebo

Study Details

VATS/RATS is widely used for diagnosis and treatment of intrathoracic conditions. Despite many benefits, postoperative pain continues to be intense after VATS/RATS. The optimal strategy for pain management has not been defined. In this randomized, placebo-controlled, double-blinded clinical investigation, investigators hypothesize that 5 mcg/kg intrathecal morphine will decrease postoperative analgesic consumption and reduce pain.

Key Dates

Start date
Sep 29, 2023
Status verified
Jun 2026
Primary completion
Jun 1, 2027
Completion
Sep 1, 2027

Study Design

Enrollment
90 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Placebo Comparator: Placebo
    Placebo, Intrathecal saline
  • Active Comparator: Morphine
    Intrathecal morphine

Primary Outcome Measure

Postoperative morphine equivalent consumption [ Time Frame: 24 hours after surgery ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of ChicagoChicagoIllinois60637
Ed Fox
[email protected]
773-834-5234

Find similar trials in Chicago, IL

By research site
University of Chicago· Chicago, IL

Related Studies