Paid Clinical Trials in California

California has 6,520 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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6,520 clinical trials

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Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

for AMI Cardiogenic Shock

10 locations incl. Jonesboro

Sponsor: Abiomed Inc.

Sex: All·Age: 18+

Code: NCT06964685·Recruiting

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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

for Alzheimer Disease

Drug: KarXT

40 locations incl. Scottsdale

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT07011732·Phase 3·Recruiting

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ELEVATE-HFpEF Clinical Study

for Heart Failure With Preserved Ejection Fraction (HFpEF)

25 locations incl. Phoenix

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 40+

Code: NCT06678841·Recruiting

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RCT for Latina Mental Health Using Web-Based Apps

for Mental Health

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06874790·Recruiting

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Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

for Migraine

35 locations incl. Flagstaff

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 70

Code: NCT06972056·Phase 4·Recruiting

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AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

for Refractory Rheumatoid Arthritis (RA)

Drug: Rituximab

31 locations incl. Tuscaloosa

Sponsor: Artiva Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06991114·Phase 2·Recruiting

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A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine

for Developmental and Epileptic Encephalopathy 1

6 locations incl. La Jolla

Sponsor: Praxis Precision Medicines

Sex: All·Age: 2 - 65

Code: NCT07010471·Phase 3·Recruiting

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An Evaluation of the Pink Cloud Application in Post- Treatment Substance Use Disorder Support

for Substance Use

1 location in Los Angeles

Sponsor: Loyola Marymount University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07042451·Recruiting

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AFO Prescription to Optimize Post-Stroke Function

for Ankle Foot Orthosis (AFO)

4 locations incl. Downey

Sponsor: University of Texas at Austin

Sex: All·Age: 18+

Code: NCT06692686·Recruiting

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Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age

for Catheter-Related Infections

6 locations incl. Birmingham

Sponsor: CorMedix

Sex: All·Age: Up to 17

Code: NCT06714864·Phase 4·Recruiting

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TriClip CED RWE Study

for Tricuspid Regurgitation

1 location in Santa Clara

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06920745·Recruiting

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Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617

for Prostate Cancer

1 location in San Francisco

Sponsor: Thomas Hope

Sex: Male·Age: 18+

Code: NCT07054346·Phase 1·Recruiting

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A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

for Major Depressive Disorder

35 locations incl. Dothan

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07076407·Phase 3·Recruiting

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Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting

for Hematopoietic and Lymphatic System Neoplasm

2 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07126301·Recruiting

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Training Reward Responsiveness Through Virtual Reality

for Positive Affect

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT07219875·Phase 2·Recruiting

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High Dose Aflibercept in Diabetic Macular Edema in Patients With Previous Vitrectomy

for Diabetic Macular Edema (DME)

Drug: Aflibercept

1 location in Fullerton

Sponsor: Retina Consultants of Orange County

Sex: All·Age: 21+

Code: NCT06662994·Phase 4·Recruiting

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The ROAR Study: Reactive Oxygen Species and Reproduction

for Ovarian Aging

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 43·Accepts healthy volunteers

Code: NCT06831019·Recruiting

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A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

for Ulcerative Colitis

21 locations incl. Escondido

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06975722·Phase 2·Recruiting

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Atacicept in Multiple Glomerular Diseases

for pMN

1 location in Brisbane

Sponsor: Vera Therapeutics, Inc.

Sex: All·Age: 10+

Code: NCT06983028·Phase 2·Recruiting

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An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-sensitive Prostate Cancer

Drug: JSB462

21 locations incl. La Jolla

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT06991556·Phase 2·Recruiting

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A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis

for Neurotrophic Keratitis

9 locations incl. Irvine

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 18+

Code: NCT06999733·Phase 1, Phase 2·Recruiting

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A Randomized, Double Blind, Placebo Controlled, Clinical Study to Examine the Benefits of an Oral Product in Panelists With Menopausal Symptoms Including Vasomotor Symptoms (VMS).

for Healthy

1 location in San Francisco

Sponsor: Olly, PBC

Sex: Female·Age: 40 - 65·Accepts healthy volunteers

Code: NCT07033013·Recruiting

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Impact of a Medical-Financial Partnership Intervention on Parent Mental Health, Perinatal Outcomes, and Child Developmental Risk

for Child Development

4 locations incl. Harbor City

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07064915·Phase 2·Enrolling By Invitation

Study of FID-022 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

1 location in Los Angeles

Sponsor: Fulgent Pharma LLC.

Sex: All·Age: 18+

Code: NCT06694480·Phase 1·Recruiting

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High Potency Cannabis: Acute and Protracted Effects

for Abuse Cannabis

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 21 - 55·Accepts healthy volunteers

Code: NCT06859723·Phase 1·Recruiting

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A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

for Castration-Resistant Prostatic Cancer

8 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06863272·Phase 1, Phase 2·Recruiting

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Imaging of Solid Tumors Using 18F-TRX

for Solid Tumor

1 location in San Francisco

Sponsor: Rahul Aggarwal

Sex: All·Age: 18+

Code: NCT06942104·Phase 1·Recruiting

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Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne

for Acne

4 locations incl. Encino

Sponsor: Sanofi Pasteur, a Sanofi Company

Sex: All·Age: 18 - 45

Code: NCT07013747·Phase 1, Phase 2·Recruiting

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Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

for Diabetic Foot Ulcer

8 locations incl. Santa Rosa

Sponsor: Cellution Biologics

Sex: All·Age: 18+

Code: NCT07014176·Phase 4·Recruiting

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A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

13 locations incl. Phoenix

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06859762·Phase 1·Recruiting

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Lebrikizumab in Moderate-to-severe Atopic Dermatitis

for Atopic Dermatitis

2 locations incl. Folsom

Sponsor: Johann E Gudjonsson MD PhD

Sex: All·Age: 18+

Code: NCT06906497·Phase 4·Recruiting

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Study With Phage for CF Subjects With Pseudomonas Lung Infection

for Chronic Pseudomonas Aeruginosa Infection

14 locations incl. Birmingham

Sponsor: BiomX Ltd

Sex: All·Age: 18+

Code: NCT06998043·Phase 2·Recruiting

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A Study of KITE-363 in Participants With Refractory Autoimmune Diseases

for Systemic Lupus Erythematosus

4 locations incl. Duarte

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18+

Code: NCT07038447·Phase 1·Enrolling By Invitation

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis With Cardiomyopathy

Drug: Nucresiran

39 locations incl. La Jolla

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07052903·Phase 3·Recruiting

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Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for Alzheimers Disease

68 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07177352·Phase 3·Recruiting

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Esophageal Manometry During Recovery From Endotracheal Intubation

for Motility Function

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 70

Code: NCT05574465·Not Yet Recruiting

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

for THC

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT05999383·Phase 2·Recruiting

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225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

for Acute Lymphoblastic Leukemia

Drug: Daratumumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06287944·Phase 1·Recruiting

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StandUPTV Habits: Feasibility Trial for Maintaining Reductions in Sedentary Screen Time

for Sedentary Behaviors

2 locations incl. Tempe

Sponsor: Arizona State University

Sex: All·Age: 23 - 64

Code: NCT06700525·Recruiting

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Observe Change in Nasal Swab DRD2 Gene Expression in Restless Legs Syndrome (RLS) Patients on Prolonged Dopamine Agonist Treatment

for Restless Leg Syndrome (RLS)

1 location in San Francisco

Sponsor: HBC Immunology Inc

Sex: All·Age: 18 - 60

Code: NCT06726785·Recruiting

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