High Potency Cannabis: Acute and Protracted Effects

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of California, Los Angeles
Study ID
NCT06859723
Phase
PHASE1
Status
Recruiting

Conditions

  • Abuse Cannabis
  • Pain
  • Pharmacokinetics

Eligibility Criteria

Sex
ALL
Age
21 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • Placebo Comparator: Placebo — DRUG
    Placebo
  • Low dose THC — DRUG
    Smoked low dose THC
  • High dose THC — DRUG
    Smoked high dose THC

Study Details

The purpose of this research is to assess the effects of smoked cananbis when cannabis is smoked during periods of cannabis use as usual and after a brief period of abstinence.

Key Dates

Start date
Jul 3, 2025
Status verified
Jun 2025
Primary completion
Jul 1, 2027
Completion
Jul 1, 2028

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Placebo Comparator: Placebo Comparator: Placebo
    0 mg THC
  • Active Comparator: Low dose THC
    50 mg THC
  • Active Comparator: High dose THC
    100 mg THC

Primary Outcome Measure

Subject-rated drug effects of abuse liability [ Time Frame: 3 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UCLA Center for Cannabis and CannabinoidsLos AngelesCalifornia90095
Vincent Acebo
310-983-3417

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