Anesthetics and Analgesics in Children

Part of paid clinical trials in Stanford, California.

Sponsor
Chi Dang Hornik
Study ID
NCT03427736
Status
Recruiting
Apply to this trial

Conditions

  • Anesthesia
  • Pain

Eligibility Criteria

Sex
ALL
Age
0 Years - 17 Years
Healthy Volunteers
Not accepted

Interventions

  • Ketorolac Tromethamine — DRUG
    IV ketorolac will be given per standard of care, not prescribed for this study
  • Hydromorphone — DRUG
    IV Hydromorphone will be given per standard of care, not prescribed for this study
  • Ketamine — DRUG
    IV Ketamine will be given per standard of care, not prescribed for this study
  • Oxycodone — DRUG
    PO Oxycodone(solution or tablet) will be given per standard of care, not prescribed for this study
  • Morphine — DRUG
    IV Morphine will be given per standard of care, not prescribed for this study

Study Details

The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.

Key Dates

Start date
Dec 13, 2018
Status verified
Apr 2026
Primary completion
Aug 30, 2027
Completion
Sep 9, 2027

Study Design

Enrollment
500 participants (estimated)

Arms

  • Arm: Drug of Interest
    Individuals receiving anesthetics or analgesics per standard of care

Primary Outcome Measure

Clearance (CL) or apparent oral clearance (CL/F) [ Time Frame: up to 48 hours post dose ]

Central Contacts

Locations (11)

FacilityCityStateZIPSite coordinators
Lucile Packard Children's HospitalStanfordCalifornia94305-
Children's Hospital ColoradoAuroraColorado80045-
Alfred I. DuPont Hospital for ChildrenWilmingtonDelaware19803-
Ann and Robert H. Lurie Childrens Hospital of ChicagoChicagoIllinois60611
Amy Fang, MD
[email protected]
1-312-227-4448
Richa Mehta
[email protected]
1-312-227-4448
Cardinal Glennon Children's HospitalSt LouisMissouri63104-
Washington University School of MedicineSt LouisMissouri63110-
Duke University Medical CenterDurhamNorth Carolina27701
Melissa Harward
[email protected]
(919) 668-3910
Chi Hornik
[email protected]
919.970.6680
Oregon Health and Science UniversityPortlandOregon97239-
Medical University of South CarolinaCharlestonSouth Carolina29425
John Costello, MD
[email protected]
843-792-9570
Mary Freeman
[email protected]
843-792-5762
Dell Children's Medical Center of TexasAustinTexas78723-
Baylor College of MedicineHoustonTexas77030-

Find similar trials in Stanford, CA

By research site
Lucile Packard Children's Hospital· Stanford, CAChildren's Hospital Colorado· Aurora, COAlfred I. DuPont Hospital for Children· Wilmington, DEAnn and Robert H. Lurie Childrens Hospital of Chicago· Chicago, ILCardinal Glennon Children's Hospital· St Louis, MOWashington University School of Medicine· St Louis, MO

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