Paid Clinical Trials in California

California has 6,520 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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6,520 clinical trials

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A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

for High-risk Myelodysplastic Syndrome

11 locations incl. Duarte

Sponsor: Crossbow Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT06994676·Phase 1·Recruiting

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

for Macular Edema Secondary to Inflammation

55 locations incl. Phoenix

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06996080·Phase 3·Recruiting

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A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

for Colon Adenocarcinoma

Drug: Calderasib

27 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06997497·Phase 3·Recruiting

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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

for Alzheimer Disease

Drug: KarXT

39 locations incl. Chandler

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT07011745·Phase 3·Recruiting

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A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

for Early Alzheimer's Disease

36 locations incl. Irvine

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 50 - 85

Code: NCT07033494·Phase 2·Recruiting

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A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

for Multiple Myeloma in Relapse

4 locations incl. Duarte

Sponsor: Kelonia Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07075185·Phase 1·Recruiting

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Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

for Bipolar II Disorder

1 location in San Francisco

Sponsor: Andrew Krystal

Sex: All·Age: 22 - 70

Code: NCT07127913·Recruiting

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Veterans Affairs Pharmacist Heart Failure Medication Titration Project 2

for Quality Improvement

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT07460219·Enrolling By Invitation

Feasibility of CGM Use in Hospitalized Youth

for Hyperglycemia

3 locations incl. San Francisco

Sponsor: University of Colorado, Denver

Sex: All·Age: 2 - 26

Code: NCT06143202·Enrolling By Invitation

Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke

for Acute Ischemic Stroke

3 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT06440707·Phase 2·Recruiting

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Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia

for Bronchopulmonary Dysplasia

3 locations incl. Palo Alto

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 12 Months

Code: NCT06534359·Recruiting

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Group Advanced Care Planning Pilot for Veterans

for Cancer

1 location in Palo Alto

Sponsor: VA Palo Alto Health Care System

Sex: All·Age: 18+

Code: NCT06646614·Recruiting

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Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

for COPD

18 locations incl. Birmingham

Sponsor: Apreo Health, Inc.

Sex: All·Age: 40 - 84

Code: NCT06891755·Recruiting

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A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)

for Chronic Hepatitis B Infection

18 locations incl. Chandler

Sponsor: Aligos Therapeutics

Sex: All·Age: 18 - 65

Code: NCT06963710·Phase 2·Recruiting

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A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy

for Kidney Disease

40 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06963827·Phase 3·Recruiting

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Ivonescimab for the Treatment of Thymic Cancer

for Thymus Carcinoma

Drug: Ivonescimab

5 locations incl. Davis

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06980077·Phase 2·Recruiting

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A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis (AD)

48 locations incl. Phoenix

Sponsor: Bluefin Biomedicine, Inc.

Sex: All·Age: 18 - 75

Code: NCT07105488·Phase 2·Recruiting

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HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

for Heart Defects, Congenital

2 locations incl. Los Angeles

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 18+

Code: NCT06175104·Recruiting

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ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study

for Healthy

2 locations incl. Pomona

Sponsor: Western University of Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06565065·Recruiting

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Electrical Stimulation for Vision Neuroenhancement in Glaucoma

for Glaucoma

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT06685211·Recruiting

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A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

for HER2-negative Breast Cancer Patients With Brain Metastases

17 locations incl. Duarte

Sponsor: Biostar Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06764940·Phase 2·Recruiting

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Shield Post-Approval Study Protocol

for Colo-rectal Cancer

56 locations incl. Chandler

Sponsor: Guardant Health, Inc.

Sex: All·Age: 45 - 81·Accepts healthy volunteers

Code: NCT06880055·Recruiting

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Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

for Acute Decompensated Heart Failure

37 locations incl. Irvine

Sponsor: Reprieve Cardiovascular, Inc

Sex: All·Age: 22+

Code: NCT06898515·Phase 3·Recruiting

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Transcranial Direct Current Stimulation for Post Treatment Lyme Disease

for Post-Treatment Lyme Disease

2 locations incl. San Francisco

Sponsor: Columbia University

Sex: All·Age: 18 - 70

Code: NCT06915324·Recruiting

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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

for Alzheimer's Disease

Drug: KarXT

28 locations incl. Long Beach

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 60 - 85

Code: NCT06976216·Phase 3·Recruiting

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Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

for Atopic Dermatitis

Drug: Nemolizumab

59 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 12+

Code: NCT06988605·Recruiting

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A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

for COVID-19 Infection

65 locations incl. Canoga Park

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07013474·Phase 3·Recruiting

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A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

for Lupus Erythematosus, Systemic

Drug: BMS-986353

40 locations incl. Scottsdale

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 16+

Code: NCT07015983·Phase 2·Recruiting

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Microbial and Cytokine Signatures in Long COVID Patients

for Post-Acute COVID-19 Syndrome

1 location in Palo Alto

Sponsor: Palo Alto Medical Foundation

Sex: All·Age: 18+

Code: NCT07074158·Enrolling By Invitation

Behavior and Risk Awareness Through Video Education for Firefighters

for Cancer Prevention

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07494617·Recruiting

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The SolanoConnex Trial: Evaluation of a Mental Health Access Project

for Mental Health

1 location in Vallejo

Sponsor: Touro University, California

Sex: All·Age: 18+

Code: NCT07306013·Recruiting

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Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer Patients

for Resectable Colorectal Carcinoma

13 locations incl. Goodyear

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07125729·Recruiting

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A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

for Chronic Spontaneous Urticaria (CSU)

Drug: Remibrutinib

128 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06868212·Phase 3·Recruiting

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Prospective Study to Assess a Diagnostic Aid for Cancer

for Cancer

39 locations incl. Coronado

Sponsor: Harbinger Health

Sex: All·Age: 45+

Code: NCT07046260·Recruiting

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

31 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting

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NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

for Schizophrenia

Drug: NBI-1117568

49 locations incl. Bryant

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 65

Code: NCT07114874·Phase 3·Recruiting

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Effects of KSM-66 Ashwagandha® (300 mg) on Skin and Hair Health in Healthy Men and Women"

for Skin Health

1 location in San Francisco

Sponsor: SF Research Institute, Inc.

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07215689·Recruiting

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Simulation Trial of Telemedical Support for Paramedics

for Emergencies

9 locations incl. Los Angeles

Sponsor: Boston Medical Center

Sex: All·Age: 21+

Code: NCT06441760·Recruiting

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XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

for Heart Transplant

14 locations incl. La Jolla

Sponsor: XVIVO Perfusion

Sex: All·Age: 18+

Code: NCT06895070·Recruiting

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The WOW Project (WOW): Wonders Of The World Through Virtual Reality for Hospitalized Children

for Virtual Reality

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 5 - 17

Code: NCT06911996·Recruiting

Apply to this trial