Paid Clinical Trials in California

California has 6,497 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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6,497 clinical trials

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The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

for Osteoporotic Fractures

2 locations incl. San Francisco

Sponsor: AO Foundation, AO Spine

Sex: All·Age: 50+

Code: NCT07027306·Recruiting

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A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

for HIV

8 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390955·Phase 1·Recruiting

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Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

22 locations incl. Birmingham

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18 - 79

Code: NCT07474792·Phase 2·Recruiting

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Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome

for Netherton Syndrome

5 locations incl. Fremont

Sponsor: Quoin Pharmaceuticals

Sex: All·Age: 4+

Code: NCT07538583·Phase 2, Phase 3·Recruiting

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Functional Substrate-Only Guided VT Ablation

for Ventricular Tachycardia

1 location in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 90

Code: NCT06464315·Enrolling By Invitation

A Study to Investigate Ubamatamab With and Without REGN7075 in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Advanced/Metastatic Non-Small Cell Lung Cancer

5 locations incl. Goodyear

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07154290·Phase 2·Recruiting

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A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

26 locations incl. Phoenix

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting

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Patient-centered Precision Medicine Lab Result Communication for Older Adults

for Chronic Kidney Disease (CKD)

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 65+

Code: NCT07391904·Enrolling By Invitation

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

for HIV Infections

17 locations incl. Beverly Hills

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT07473778·Recruiting

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177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer

for Metastatic Prostate Cancer

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Male·Age: 18+

Code: NCT07145177·Phase 1·Recruiting

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A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

for Hepatocellular Carcinoma (HCC)

Drug: Ipilimumab

9 locations incl. Los Angeles

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07291076·Phase 1, Phase 2·Recruiting

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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

for Obesity or Overweight

Drug: Enicepatide

25 locations incl. Anniston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07351045·Phase 3·Recruiting

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Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US

for Overweight or Obesity

3 locations incl. Walnut Creek

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07431086·Phase 2·Recruiting

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Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

for Schizophrenia

Drug: GXV813

7 locations incl. Bentonville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07467993·Phase 2·Recruiting

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AI-Supported Cognitive Rehabilitation for Older Adults With Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

1 location in Pasadena

Sponsor: Kaiser Permanente

Sex: All·Age: 65+

Code: NCT07474038·Enrolling By Invitation

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

for Neovascular Age-Related Macular Degeneration (nAMD)

46 locations incl. Phoenix

Sponsor: Adverum Biotechnologies, Inc.

Sex: All·Age: 50+

Code: NCT07482176·Phase 3·Recruiting

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A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for Idiopathic Hypersomnia

12 locations incl. Santa Monica

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07500090·Phase 3·Recruiting

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Vibrotactile Coordinated Reset for Spasticity After Spinal Cord Injury

for Spasticity, Muscle

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT06290609·Not Yet Recruiting

Ceribell Delirium Monitor Outcomes Pilot Study

for Delirium in the Intensive Care Unit

1 location in Irvine

Sponsor: Ceribell Inc.

Sex: All·Age: 18+

Code: NCT07449416·Not Yet Recruiting

Reliability, Validity, and Acceptability of a Novel Visual Scale for Estimating Daily Methamphetamine Use Among People Who Use Methamphetamine

for Methamphetamine Disorders

1 location in San Francisco

Sponsor: Phillip Coffin, MD, MIA

Sex: All·Age: 20 - 40·Accepts healthy volunteers

Code: NCT07464873·Not Yet Recruiting

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

for PROC

12 locations incl. Little Rock

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07470853·Phase 1·Recruiting

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Endotype DIrected Treatment for OSA in Down Syndrome

for Obstructive Sleep Apnea (OSA)

5 locations incl. Tucson

Sponsor: University of Arizona

Sex: All·Age: 6+

Code: NCT07280468·Phase 4·Recruiting

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Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

for Advanced Renal Cell Carcinoma

4 locations incl. La Jolla

Sponsor: Karie Runcie

Sex: All·Age: 18+

Code: NCT06863311·Phase 2·Recruiting

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A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Drug: Nivolumab

34 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221149·Phase 2, Phase 3·Recruiting

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A Study of Efimosfermin Alfa in Adults With Hepatic Impairment

for Non-alcoholic Fatty Liver Disease

3 locations incl. Rialto

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 70

Code: NCT07358546·Phase 1·Recruiting

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SPACE for Youth With Chronic Pain

for Chronic Pain

2 locations incl. Palo Alto

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 17

Code: NCT07425691·Recruiting

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MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial

for Adult Obesity

Drug: Semaglutide

15 locations incl. Birmingham

Sponsor: Eccogene

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07505303·Phase 2·Not Yet Recruiting

Experiences w/ & Attitudes Towards Immune Chckpt Inhibitors in NSCLC Patients Single Center Survey Based Study

for Lung Non-Small Cell Carcinoma

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT07339254·Recruiting

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A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

40 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361510·Phase 3·Recruiting

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An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps

for Chronic Rhinosinusitis With Nasal Polyps

2 locations incl. La Mesa

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07424144·Phase 3·Enrolling By Invitation

A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea

for Functional Hypothalamic Amenorrhea (FHA)

6 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18 - 40

Code: NCT07235917·Phase 2·Recruiting

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Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis

for Psoriatic Arthritis

Drug: Zasocitinib

1 location in Fountain Valley

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07286058·Phase 3·Recruiting

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A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

5 locations incl. San Francisco

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 18+

Code: NCT07287150·Phase 2·Recruiting

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Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

for Knee Cartilage Defects

17 locations incl. Birmingham

Sponsor: Medipost, Inc.

Sex: All·Age: 18 - 75

Code: NCT07339111·Phase 3·Recruiting

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Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

for Urothelial Cancer

Drug: PF-08634404

39 locations incl. Fayetteville

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07421700·Phase 1, Phase 2·Recruiting

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Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)

for Direct Care Workers

6 locations incl. San Diego

Sponsor: Rendever, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07430371·Recruiting

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Shatavari Root Extract for Perimenopausal Symptoms

for Perimenopause

1 location in San Francisco

Sponsor: SF Research Institute, Inc.

Sex: Female·Age: 40 - 45·Accepts healthy volunteers

Code: NCT07441109·Not Yet Recruiting

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

for Type 1 Diabetes

Drug: Adalimumab

11 locations incl. San Francisco

Sponsor: City of Hope Medical Center

Sex: All·Age: 9 - 20

Code: NCT07061574·Phase 1, Phase 2·Recruiting

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A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease

for Systemic Lupus Erythematosus (SLE)

Drug: Enpatoran

5 locations incl. Los Angeles

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: 18 - 75

Code: NCT07332481·Phase 3·Recruiting

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Virtual Reality for ICU Delirium Prevention

for ICU Delirium

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07357389·Recruiting

Apply to this trial