Virtual Reality for ICU Delirium Prevention

Conditions

• ICU Delirium

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Accepted

Interventions

• Virtual Reality therapeutics — DEVICE
  Patients will receive daily VR sessions for up to 5 days in addition to regular delirium prevention measures in the ICU

Study Details

The purpose of this study is to evaluate whether daily exposure to immersive virtual reality (VR) can reduce the incidence of delirium in high-risk, non-intubated ICU patients. Participants will be randomized to either standard ICU care or standard care plus once-daily 15-minute VR sessions consisting of calming natural scenes, guided meditation, and music. The study population includes adult surgical ICU patients at Cedars-Sinai who are CAM-ICU negative at enrollment and possess at least one established risk factor for delirium. Outcomes will include the incidence and duration of delirium, ICU and hospital length of stay, feasibility of the VR intervention, and the frequency of adverse events. By targeting a high-risk population with an innovative non-pharmacologic therapy, this trial aims to generate data to support integration of VR into ICU delirium prevention protocols.

Key Dates

Start date

Mar 10, 2026

Status verified

Jan 2026

Primary completion

Jan 15, 2028

Completion

Apr 30, 2028

Study Design

Enrollment

822 participants (estimated)

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Arms

• No Intervention: Standard ICU delirium prevention
• Experimental: Study ICU Delirium Prevention and VR treatment

Primary Outcome Measure

Incidence of ICU Delirium [ Time Frame: From enrollment in the study until ICU discharge. Assessed Day 1 in the morning and evening for the duration of the ICU admission, up to 24 months from enrollment. ]

Central Contacts

• Devon S Callahan, MD
  310-423-2402
  [email protected]

Locations (1)

Find similar trials in Los Angeles, CA

Related Studies

• Exogenous Ketone Supplementation in ICU Delirium
  PHASE1 · Recruiting · Vanderbilt University Medical Center · Nashville, Tennessee