Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US

Part of paid clinical trials in Walnut Creek, California.

Sponsor
Regeneron Pharmaceuticals
Study ID
NCT07431086
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

  • Overweight or Obesity

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Olatorepatide — DRUG
    Administered per the protocol
  • Placebo — DRUG
    Administered per the protocol

Study Details

This study will test olatorepatide (study drug) to determine how safe and effective this drug is and how easily your body can accept this drug without causing side effects, as well as how the drug is processed in the body by participants with overweight or obesity. The study will test how safe and effective the study drug works compared to placebo in people who are overweight or obese but do not have diabetes. The study is looking at: * What side effects the study drug might cause * How much the study drug is in the blood at different times * How well the study drug works * If the body makes antibodies to the study drug as this may cause the study drug to not work as well

Key Dates

Start date
Mar 16, 2026
Status verified
Apr 2026
Primary completion
Nov 23, 2026
Completion
Dec 28, 2026

Study Design

Enrollment
120 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: General Cohort
  • Experimental: Subgroup Cohort

Primary Outcome Measure

Occurrence of Treatment-Emergent Adverse Events (TEAEs) [ Time Frame: Up to approximately 30 weeks ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Diablo Clinical Research - Flourish ResearchWalnut CreekCalifornia94598-
Clinical Site Partners, LLC DBA Flourish ResearchWinter ParkFlorida32789-
Flourish Research - San Antonio Medical TrialsSan AntonioTexas78229-

Find similar trials in Walnut Creek, CA

By research site
Diablo Clinical Research - Flourish Research· Walnut Creek, CAClinical Site Partners, LLC DBA Flourish Research· Winter Park, FLFlourish Research - San Antonio Medical Trials· San Antonio, TX

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