Paid Clinical Trials in California

California has 6,497 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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6,497 clinical trials

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Open-Label Extension Study to Pioneer Study 6058-SCD-101

for Sickle Cell Disease

8 locations incl. Little Rock

Sponsor: Fulcrum Therapeutics

Sex: All·Age: 18+

Code: NCT07401823·Phase 2·Enrolling By Invitation

Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety

for Generalized Anxiety Disorder (GAD)

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT07430800·Recruiting

Apply to this trial

Kimchi and Gut Health

for Healthy Adult Participants

2 locations incl. Davis

Sponsor: University of California, Davis

Sex: All·Age: 19 - 70·Accepts healthy volunteers

Code: NCT07435831·Recruiting

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Neuronal Mechanisms of Learning and Utilizing Abstract Representations

for Epilepsy Intractable

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT07454785·Enrolling By Invitation

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

for Healthy Participants

2 locations incl. Glendale

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07511205·Phase 1·Recruiting

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A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease

for Primary Membranous Nephropathy

6 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT07571746·Phase 2·Recruiting

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Direct Comparison of Cardiac CT With TEE to Evaluate Watchman FLX LAA Occluder Device Characteristics

for Device Related Thrombosis

5 locations incl. Los Angeles

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+

Code: NCT06523166·Recruiting

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Rapid Non-Invasive Brain Stimulation for Hoarding Disorder

for Hoarding Disorder

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 70

Code: NCT06712914·Recruiting

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A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

for Macular Degeneration

30 locations incl. Springdale

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07440225·Phase 2, Phase 3·Recruiting

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A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

for Nausea and Vomiting

10 locations incl. Los Angeles

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07446439·Phase 3·Recruiting

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Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets

for Type 2 Diabetes

16 locations incl. Birmingham

Sponsor: Biomea Fusion Inc.

Sex: All·Age: 18 - 70

Code: NCT07502495·Phase 2·Recruiting

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A Clinical Study of GeminiOne TEER System for the Treatment of Severe, Symptomatic MR.

for Mitral Regurgitation

1 location in Thousand Oaks

Sponsor: Sierra Valve LLC

Sex: All·Age: 18+

Code: NCT07086534·Recruiting

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A Phase 1b Study of Adenylosuccinic Acid (ASA-001) for Adenylosuccinate Synthase 1 (ADSS1) Deficient Myopathy.

for Adenylosuccinate Synthase 1 Deficient Myopathy

1 location in Los Angeles

Sponsor: Cure ADSSL1

Sex: All·Age: 18+

Code: NCT07412821·Phase 1·Enrolling By Invitation

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis (UC)

Drug: LY4268989

49 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07415044·Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy

for Narcolepsy

17 locations incl. Santa Ana

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT07493265·Phase 2·Recruiting

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A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

for Alzheimer Disease

Drug: KarXT

6 locations incl. Gilbert

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT06947941·Phase 3·Recruiting

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Final Prototype Refinement of Adaptive Cell Phone Support

for Medication Adherence

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 15 - 20

Code: NCT07084155·Recruiting

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A Multi Center Study Testing a New Implant for Adults With Severe Emphysema

for Emphysema or COPD

3 locations incl. San Francisco

Sponsor: Pulmair Medical, Inc.

Sex: All·Age: 22+

Code: NCT07119229·Recruiting

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Transition to KPL-387 Monotherapy Dosing & Administration Study

for Recurrent Pericarditis

14 locations incl. Phoenix

Sponsor: Kiniksa Pharmaceuticals International, plc

Sex: All·Age: 18 - 80

Code: NCT07288216·Phase 2·Recruiting

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Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain

for Gulf War Illness

1 location in San Diego

Sponsor: Veterans Medical Research Foundation

Sex: All·Age: 18 - 65

Code: NCT07325513·Recruiting

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Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia

for Schizophrenia

13 locations incl. Bentonville

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07363577·Phase 3·Recruiting

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Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

for Low-grade Glioma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 25

Code: NCT07506239·Recruiting

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ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1

for Depressed Mood

2 locations incl. La Jolla

Sponsor: Salma Health, Inc.

Sex: All·Age: 18+

Code: NCT07528014·Recruiting

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BETA: Study in Prediabetes Type 2 Diabetes

for Prediabetes

1 location in San Francisco

Sponsor: 4YouandMe

Sex: All·Age: 18+

Code: NCT07598773·Enrolling By Invitation

A Long-Term Observational Study of Patients With Fucosidosis

for Fucosidosis

2 locations incl. Orange

Sponsor: JCR Pharmaceuticals Co., Ltd.

Sex: All·Age: All ages

Code: NCT07615400·Recruiting

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Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

for Breast Neoplasms

39 locations incl. Birmingham

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07214532·Recruiting

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A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

for Colitis Ulcerative

8 locations incl. Anaheim

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 75

Code: NCT07463183·Phase 2·Recruiting

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Continuous Dual Aspiration Technique With Zoom System for Stroke

for Ischemic Stroke

13 locations incl. Huntsville

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07491952·Recruiting

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Empowering Youth With School Discipline Referrals as Peer Coaches

for Disruptive Behavior

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 10 - 15

Code: NCT07515742·Recruiting

Apply to this trial

PhIbRandomGemcitabine(G)w/or w/Out Pitavastatin(P)MainTx UnresecPancreaticAdenocarcinoma(uPDAC)

for Pancreatic Cancer

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07549958·Phase 1·Recruiting

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Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities

for Tobacco-Related Carcinoma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07049757·Recruiting

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A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

for Multiple Sclerosis (MS) Primary Progressive

11 locations incl. Pheonix

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07067463·Phase 3·Recruiting

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Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

for Advanced Clear Cell Renal Cell Carcinoma

Drug: Ipilimumab

2 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07128680·Phase 1·Recruiting

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Pregnancy and Postpartum Breastfeeding Support for Patients With Gestational Diabetes

for Gestational Diabetes Mellitus (GDM)

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07176793·Recruiting

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A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis

12 locations incl. Phoenix

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07299019·Phase 3·Recruiting

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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

for Obesity or Overweight

Drug: Enicepatide

28 locations incl. Guntersville

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07351058·Phase 3·Recruiting

Apply to this trial

PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

for Proteinuric Kidney Diseases

25 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT07355296·Phase 2·Recruiting

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A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults

for Influenza

10 locations incl. San Bernardino

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07496450·Phase 3·Recruiting

Apply to this trial

Efficacy and Safety of Shatavari Root Extract for Premenstrual Syndrome in Women

for Premenstrual Syndrome

1 location in San Francisco

Sponsor: SF Research Institute, Inc.

Sex: Female·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07441096·Not Yet Recruiting

A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234

for Hepatic Impairment

4 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07546760·Phase 1·Recruiting

Apply to this trial