Paid Clinical Trials in California

California has 6,497 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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6,497 clinical trials

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The Cervical "STRETCH" Study

for Cervical Spine

1 location in Pomona

Sponsor: Western University of Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07440030·Not Yet Recruiting

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

for Sickle Cell Disease

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18 - 80

Code: NCT06016634·Phase 2·Recruiting

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Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry-Guided Breathing Therapy

for Written Exposure Therapy

2 locations incl. Little Rock

Sponsor: Stanford University

Sex: Female·Age: 18+

Code: NCT07342530·Recruiting

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Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG)

for Glioblastoma

1 location in San Francisco

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 3 - 39

Code: NCT07389278·Phase 1, Phase 2·Not Yet Recruiting

A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo

for Non-segmental Vitiligo

Drug: GIA632

18 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 99

Code: NCT07431177·Phase 2·Recruiting

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A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: FWY003

12 locations incl. Huntington Beach

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50+

Code: NCT07441642·Phase 2·Recruiting

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A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults

for Influenza, Human+COVID-19

2 locations incl. San Diego

Sponsor: GlaxoSmithKline

Sex: All·Age: 65 - 85

Code: NCT07464314·Phase 1·Recruiting

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Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure

for Iron Deficiency (ID)

1 location in Pleasanton

Sponsor: Kaiser Permanente

Sex: All·Age: 18+

Code: NCT07467668·Not Yet Recruiting

A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors

for Advanced NRAS-Mutant Melanoma

6 locations incl. Los Angeles

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07584226·Phase 1·Recruiting

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Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

52 locations incl. Tucson

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting

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177^Lu-PSMA-617 in Combination With Sipuleucel-T for the Treatment of Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Adenocarcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Male·Age: 18+

Code: NCT07219147·Phase 1·Recruiting

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Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment

for Dry Eye

1 location in Berkeley

Sponsor: University of California, Berkeley

Sex: All·Age: 18+

Code: NCT07606625·Phase 4·Recruiting

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A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

for CRC (Colorectal Cancer)

Drug: Bevacizumab

80 locations incl. Chandler

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07284849·Phase 3·Recruiting

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A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

for Lupus Erythematosus, Systemic

Drug: Nipocalimab

29 locations incl. Beverly Hills

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 75

Code: NCT07438496·Phase 3·Recruiting

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A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

for Overweight or Obesity and Elevated Liver Fat

22 locations incl. Chandler

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07441252·Phase 2·Recruiting

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Blastocyst AI Assisted Morphokinetics in ART

for Infertility Assisted Reproductive Technology

1 location in Clovis

Sponsor: Viable Biosciences

Sex: Female·Age: 18 - 45

Code: NCT07611448·Enrolling By Invitation

Getinge's Beating Heart Product Family Post-Market Clinical Follow-up (PMCF) Study

for Off Pump Coronary Artery Bypass Surgery

2 locations incl. Stockton

Sponsor: Maquet Cardiovascular

Sex: All·Age: 22+

Code: NCT07286890·Recruiting

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HMPL-A580 in Participants With Advanced or Metastatic Solid Tumor

for Solid Tumors, Adult

Drug: HMPL-A580

5 locations incl. Orange

Sponsor: Hutchmed

Sex: All·Age: 18+

Code: NCT07396584·Phase 1, Phase 2·Recruiting

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Efficacy and Safety of Ribupatide (KAI-9531) Administered Once Weekly in Participants Living With Obesity Who Do Not Have Diabetes

for Obesity

35 locations incl. Mesa

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07458269·Phase 2·Enrolling By Invitation

ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression

for Depression

2 locations incl. Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 60

Code: NCT06408246·Phase 2·Recruiting

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A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

15 locations incl. Irvine

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting

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A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

6 locations incl. Irvine

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07227025·Phase 1, Phase 2·Recruiting

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Objective Assessment of Intraocular Lens Tilt and Decentration

for Tilt and Decentration

2 locations incl. Bakersfield

Sponsor: Johnson & Johnson Surgical Vision, Inc.

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07324200·Recruiting

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Auricular Acupuncture on Emotional Distress in Service Members and Veterans With PTSD

for PTSD and Substance Use Disorder

2 locations incl. Fairfield

Sponsor: United States Naval Medical Center, San Diego

Sex: All·Age: 18 - 65

Code: NCT07021352·Recruiting

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Fructose Intestinal Gluconeogenesis

for Healthy Participants

1 location in Vallejo

Sponsor: Touro University, California

Sex: All·Age: 20 - 55·Accepts healthy volunteers

Code: NCT07209202·Recruiting

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Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

for Open Angle Glaucoma (OAG)

4 locations incl. Glendale

Sponsor: Life Biosciences Inc.

Sex: All·Age: 40 - 85

Code: NCT07290244·Phase 1·Recruiting

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Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

for Solid Tumors

5 locations incl. Los Angeles

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07374848·Phase 1·Recruiting

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Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)

for PTSD

1 location in Sunnyvale

Sponsor: Acacia Clinics

Sex: All·Age: 18 - 70

Code: NCT07523685·Recruiting

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A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia

for Schizophrenia

8 locations incl. Garden Grove

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 55

Code: NCT07615426·Phase 1·Recruiting

Apply to this trial

Ketamine for Veterans With Parkinson's Disease

for Parkinson's Disease

1 location in San Francisco

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 80

Code: NCT06231563·Phase 2·Recruiting

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The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function

for Dry Eye Disease (DED)

1 location in Fullerton

Sponsor: Southern California College of Optometry at Marshall B. Ketchum University

Sex: All·Age: 18+

Code: NCT06655441·Phase 4·Recruiting

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Qnnections: Refinement and Pilot Trial of a Suicide Prevention Intervention to Increase Social Connection

for Suicidal Thoughts and Behaviors

1 location in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06803329·Recruiting

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Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)

for Toxicant Exposure

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Male·Age: 18+

Code: NCT07226440·Phase 1, Phase 2·Recruiting

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Characterizing Drug Liking During Drug Administration in Peri-procedural Clinical Settings

for Drug Liking

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT07348172·EARLY_Phase 1·Not Yet Recruiting

RCT of HeartBot in Women

for Participants Must be Women Aged 25 Years or Older

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 25+·Accepts healthy volunteers

Code: NCT07416734·Not Yet Recruiting

Intraoperative Wound Irrigation for Pilonidal Disease

for Pilonidal Disease

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 8 Months - 30

Code: NCT07417202·Recruiting

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Assess Injectable Hyaluronic Acid Gel for the Treatment of Volume Loss, Skin Laxity and Fine Lines

for Fine Lines

1 location in San Diego

Sponsor: Goldman, Butterwick, Fitzpatrick and Groff

Sex: All·Age: 30 - 75·Accepts healthy volunteers

Code: NCT07421544·Phase 4·Not Yet Recruiting

Virtual Reality (VR) for Interventional Radiology (IR) Procedures

for Pain

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 8+

Code: NCT07427862·Recruiting

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FEAST Perinatal Support Program Intervention

for Diet, Healthy

1 location in Los Angeles

Sponsor: University of Southern California

Sex: Female·Age: 18+

Code: NCT06715787·Recruiting

Apply to this trial

Treating Young Children With Attention Deficit Hyperactivity Disorder

for Attention-Deficit/Hyperactivity Disorder (ADHD)

5 locations incl. Palo Alto

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3 - 5

Code: NCT07300956·Phase 4·Not Yet Recruiting